5 Questions
What is the stage of cell wall peptidoglycan synthesis inhibited by glycopeptides?
Second stage
What is the site of action of glycopeptides in peptidoglycan synthesis?
Binding to the D-alanyl-D-alanine precursor peptide side chain
What is the consequence of glycopeptide binding to the D-alanyl-D-alanine precursor peptide side chain?
Prevention of murein monomer assembly into peptidoglycan
Which of the following antibiotics is NOT a representative of glycopeptides?
Penicillin
What is the unique feature of vancomycin molecule that allows it to bind to the D-alanyl-D-alanine precursor peptide side chain?
Presence of a binding pocket
Learn about the mechanism of action of glycopeptides antibiotics, such as Vancomycin and Teicoplanin, including how they inhibit peptidoglycan synthesis and bind to the D-alanyl-D-alanine precursor peptide side chain. Understand the role of glycopeptides in preventing murein monomer assembly into peptidoglycan.
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