BIOCHEM-C Glucose Homeostasis & Fuel Metabolism - Dra. Flores

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What are the three sources of glucose for the body?

Glycogenolysis, gluconeogenesis, ketone bodies

Glycogenolysis, glycolysis, lipolysis

Glycogenolysis, lipogenesis, ketogenesis

Intestinal absorption of food, glycolysis, gluconeogenesis (correct)

What can glucose be stored as once transported into cells?

Glycogen (correct)

Ketone bodies

Triglycerides

Fatty acids

What is the ultimate long-term energy-storage material derived from excess glucose?

Alanine

Triglycerides (correct)

Fatty acids

Lactate

Which process involves the conversion of excess glucose to fatty acids?

Lipogenesis Signup and view all the answers

Which molecules are the main substrates for gluconeogenesis?

Lactate Signup and view all the answers

What is the primary energy source during prolonged fasting and prolonged exercise?

Fatty acids Signup and view all the answers

Which organ is responsible for the bulk of glucose output during fasting?

Liver Signup and view all the answers

During prolonged fasting, what is stored in the adipose tissue?

Triglycerides Signup and view all the answers

Which statement is true about muscle energy sources?

Muscle uses both glucose and fatty acids as energy sources. Signup and view all the answers

What is the main function of alanine and lactate in muscle?

They contribute to gluconeogenesis by being transported to the liver. Signup and view all the answers

In which tissues does glycogenolysis occur with the release of cellular glucose into the bloodstream?

Muscle and liver Signup and view all the answers

What is the primary fuel used by the brain?

Glucose Signup and view all the answers

Which hormone is centrally important in orchestrating the switch from glycogen synthesis after meals to glycogen breakdown and gluconeogenesis?

Insulin Signup and view all the answers

What is the primary function of insulin during a surge in its concentration?

Inhibits glucose production Signup and view all the answers

Which hormone(s) counteract the effects of insulin and promote glycogenolysis, gluconeogenesis, and lipolysis?

Glucagon, catecholamines, cortisol, and growth hormone Signup and view all the answers

What controls insulin secretion in the β-cell?

Glucose metabolism Signup and view all the answers

What effect does the increase in ATP/ADP ratio have on the cell?

It closes the ATP-sensitive potassium channels, decreasing potassium efflux and depolarizing the cell Signup and view all the answers

What is the function of C-peptide as mentioned in the text?

It serves as a marker of beta cell function Signup and view all the answers

What happens when insulin attaches to its receptor according to the text?

It activates tyrosine kinase activity, causing the enzyme to dephosphorylate Signup and view all the answers

Which substances can also stimulate insulin secretion according to the text?

Amino acids and free fatty acids Signup and view all the answers

What is the role of PDK1 in the IRS-PI3K-Akt signaling pathway?

Phosphorylates the Akt kinase Signup and view all the answers

Which protein is involved in the PI3K-independent pathway that stimulates glucose transport?

TC-10 Signup and view all the answers

What does the activation of some isoforms of protein kinase C (PKC) regulate in the IRS-PI3K-Akt signaling pathway?

Glucose transport Signup and view all the answers

What is a key concept in glucose homeostasis and crucial to understanding the pathogenesis of type 2 diabetes?

Insulin resistance Signup and view all the answers

BIOCHEM-C Glucose Homeostasis & Fuel Metabolism - Dra. Flores - 2023-01

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Podcast

Questions and Answers

What are the three sources of glucose for the body?

What can glucose be stored as once transported into cells?

What is the ultimate long-term energy-storage material derived from excess glucose?

Which process involves the conversion of excess glucose to fatty acids?

Which molecules are the main substrates for gluconeogenesis?

What is the primary energy source during prolonged fasting and prolonged exercise?

Which organ is responsible for the bulk of glucose output during fasting?

During prolonged fasting, what is stored in the adipose tissue?

Which statement is true about muscle energy sources?

What is the main function of alanine and lactate in muscle?

In which tissues does glycogenolysis occur with the release of cellular glucose into the bloodstream?

What is the primary fuel used by the brain?

Which hormone is centrally important in orchestrating the switch from glycogen synthesis after meals to glycogen breakdown and gluconeogenesis?

What is the primary function of insulin during a surge in its concentration?

Which hormone(s) counteract the effects of insulin and promote glycogenolysis, gluconeogenesis, and lipolysis?

What controls insulin secretion in the β-cell?

What effect does the increase in ATP/ADP ratio have on the cell?

What is the function of C-peptide as mentioned in the text?

What happens when insulin attaches to its receptor according to the text?

Which substances can also stimulate insulin secretion according to the text?

What is the role of PDK1 in the IRS-PI3K-Akt signaling pathway?

Which protein is involved in the PI3K-independent pathway that stimulates glucose transport?

What does the activation of some isoforms of protein kinase C (PKC) regulate in the IRS-PI3K-Akt signaling pathway?

What is a key concept in glucose homeostasis and crucial to understanding the pathogenesis of type 2 diabetes?

More Like This

TERM 1 WEEK 10

4-L1+

Carbohydrate Metabolism & Glycogen Synthesis

Glycogen Synthesis and Breakdown

Upgrade to continue

BIOCHEM-C Glucose Homeostasis &amp; Fuel Metabolism - Dra. Flores - 2023-01

Choose a study mode

Podcast

Questions and Answers

What are the three sources of glucose for the body?

What can glucose be stored as once transported into cells?

What is the ultimate long-term energy-storage material derived from excess glucose?

Which process involves the conversion of excess glucose to fatty acids?

Which molecules are the main substrates for gluconeogenesis?

What is the primary energy source during prolonged fasting and prolonged exercise?

Which organ is responsible for the bulk of glucose output during fasting?

During prolonged fasting, what is stored in the adipose tissue?

Which statement is true about muscle energy sources?

What is the main function of alanine and lactate in muscle?

In which tissues does glycogenolysis occur with the release of cellular glucose into the bloodstream?

What is the primary fuel used by the brain?

Which hormone is centrally important in orchestrating the switch from glycogen synthesis after meals to glycogen breakdown and gluconeogenesis?

What is the primary function of insulin during a surge in its concentration?

Which hormone(s) counteract the effects of insulin and promote glycogenolysis, gluconeogenesis, and lipolysis?

What controls insulin secretion in the β-cell?

What effect does the increase in ATP/ADP ratio have on the cell?

What is the function of C-peptide as mentioned in the text?

What happens when insulin attaches to its receptor according to the text?

Which substances can also stimulate insulin secretion according to the text?

What is the role of PDK1 in the IRS-PI3K-Akt signaling pathway?

Which protein is involved in the PI3K-independent pathway that stimulates glucose transport?

What does the activation of some isoforms of protein kinase C (PKC) regulate in the IRS-PI3K-Akt signaling pathway?

What is a key concept in glucose homeostasis and crucial to understanding the pathogenesis of type 2 diabetes?

More Like This

TERM 1 WEEK 10

4-L1+

Carbohydrate Metabolism & Glycogen Synthesis

Glycogen Synthesis and Breakdown

BIOCHEM-C Glucose Homeostasis & Fuel Metabolism - Dra. Flores - 2023-01