TERM 1 WEEK 10

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Liver glycogen is used in fasting to provide glucose for use by other tissues including the brain. Muscle glycogen is not. What is the explanation for this?

A) Muscle does not have a debranching enzyme.

B) Muscle cannot degrade glycogen further than glucose-1-phosphate

C) Muscle lacks glucose-6-phosphatase. (correct)

D) The liver provides all the glucose necessary for metabolism and there is no need for muscle to do the same.

Which of the following is NOT a function of glucagon?

Raising blood glucose levels

Stimulating glycogen production from glucose

C) Stimulating the release of glucose from the liver

) Increasing glucose production from fatty acid (correct)

) Which of pathway for glycogen breakdown in the liver would prevent the cell from breaking down glycogen in response to EPINEPHRINE

One that prevents it from hydrolyzing GTP

. One that destroys its GTPase activity

. One that prevents it from binding GTP

One that causes it to constitutively (constantly) activate Phospholipase C (correct)

When glucose enters the beta cell, it is used to produce ATP. The increase in ATP causes an influx of a substance which causes the exocytosis of insulin. What is this substance?

) Ca2+ Signup and view all the answers

Which of the following statements regarding glucose is not true?

A high blood glucose concentration is called hypoglycaemia. Signup and view all the answers

Which of the following statements regarding glycogenolysis is not true?

Glycogenolysis helps correct hypoglycaemia. Signup and view all the answers

. Which of the following statements is false about gluconeogenesis?

From the hydrolysis of tri-acyl-glycerol, fatty acids can be used as a carbon source Signup and view all the answers

During gluconeogensis, the three irreversible steps of glycolysis have to be bypassed. Final step is the conversion of glucose-6-P to glucose that is catalyzed by glucose-6- phosphatase. Which of the following statement is true about the reaction step?

Defect in glucose-6-phosphatase leads to abnormal accumulation of glycogen in liver Signup and view all the answers

Which of the following Glucose transporters is Insulin-dependent?

) GLUT4 Signup and view all the answers

Which of the following statements about gluconeogenesis is correct?

Gluconeogenesis enables the liver to maintain blood glucose levels during starvation Signup and view all the answers

. In the glycogen synthase reaction, the precursor to glycogen is:

B. UDP-glucose Signup and view all the answers

Which of the following statements is NOT true about the synthesis of glycogen?

glycogen synthase needs to be phosphorylated Signup and view all the answers

Why is glycogen branching important?

Both to increase solubility and to increase faster glycogen breakdown Signup and view all the answers

A defect in branching enzyme

Severe cases will not result in Cirrhosis or death in the very young. Signup and view all the answers

which of the following enzymes is not an irreversible enzyme in glycolysis or gluconeogenesis?

Glycogen synthase in glycolysis Signup and view all the answers

What are the main differences between glycolysis and gluconeogenesis? Which one of the statement is incorrect

Glycogen synthase in glycolysis Signup and view all the answers

Q .What are the main differences between glycolysis and gluconeogenesis? Which of the statement is correct?

a. Glycolysis takes place in all parts of the body whereas gluconeogenesis mainly happens in the liver. Besides glycolysis is stimulated by insulin, is a catabolic process, exergonic, and its final product is pyruvate. On the contrary, gluconeogenesis is anabolic, endergonic, and its final product is glucose Signup and view all the answers

TERM 1 WEEK 10

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