Questions and Answers
What is the therapeutic classification of glyburide?
What is the pharmacologic classification of glyburide?
How is glyburide administered?
Which of the following are side effects of glyburide?
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What are some nursing implications when administering glyburide?
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What should clients be taught regarding glyburide?
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What is the primary action of glyburide?
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What additional information should be considered when administering glyburide?
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What is the generic name of glyburide?
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What is the brand name of glyburide?
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Study Notes
Glyburide Overview
- Glyburide, known by the brand name DiaBeta, falls under the therapeutic classification of antidiabetic medications.
- It belongs to the pharmacologic class of sulfonylureas, which lower blood sugar levels.
Administration and Dosage
- Administered orally (PO) for effective diabetes management.
Side Effects
- Potential adverse effects include:
- Hypoglycemia (low blood sugar)
- Photosensitivity (increased sensitivity to sunlight)
- Dizziness
- Aplastic anemia (failure of blood cell production)
- Pancytopenia (reduction of red and white blood cells and platelets)
Nursing Implications
- Primarily used to control blood glucose levels in Type 2 diabetes mellitus when diet alone is insufficient; necessitates some remaining pancreatic function.
- Recommend using sunscreen to mitigate photosensitivity reactions.
- Patients should report unusual symptoms including weight gain, swelling, drowsiness, shortness of breath, muscle cramps, weakness, sore throat, rash, or abnormal bleeding/bruising to their healthcare provider.
Client Education
- Educate on signs and symptoms of hypoglycemia (low blood sugar) and hyperglycemia (high blood sugar).
- Instruct patients to monitor their blood sugar levels and avoid taking the medication if unable to eat.
- Advise against alcohol consumption, which can exacerbate side effects.
- Patients should carry a form of sugar and identification detailing their condition and medication regimen at all times.
- Follow a prescribed diet, medication, and exercise plan closely.
- Stress the importance of monitoring blood sugar and ketones during periods of stress or illness.
Mechanism of Action
- Glyburide lowers blood glucose by stimulating insulin release from the pancreas and enhancing the sensitivity of insulin receptors.
- It may also reduce hepatic (liver) glucose production.
Additional Considerations
- Assess for any known allergies to sulfonamides prior to administration.
- Administer with breakfast to improve absorption and efficacy.
- Regularly monitor complete blood count (CBC) as glyburide may cause reductions in blood counts and increase liver enzymes (AST, LDH) and kidney function markers (BUN, creatinine).
- Onset of action occurs within 45-60 minutes, with peak effectiveness at 1.5-3 hours, and duration lasting approximately 24 hours.
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Description
This quiz covers essential information about Glyburide, an antidiabetic medication commonly used for managing Type 2 diabetes. It includes details on administration, potential side effects, and important nursing implications for effective patient management. Test your understanding and knowledge of Glyburide in a clinical context.
