Glyburide Flashcards
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Questions and Answers

What are the brand names of Glyburide?

  • Diabeta
  • Micronase
  • Both Micronase and Diabeta (correct)
  • No brand names
  • What is the generic name for the medication Glyburide?

    Glyburide

    What is Glyburide indicated for?

    As an adjunct to diet in the treatment of non-insulin dependent diabetes mellitus.

    What is the usual initial dose of Glyburide?

    <p>1.25 to 5 mg</p> Signup and view all the answers

    What is the maximum recommended daily dosage of Glyburide?

    <p>20 mg</p> Signup and view all the answers

    What are the strengths of Glyburide tablets available?

    <p>1.25 mg, 2.5 mg, 5.0 mg</p> Signup and view all the answers

    What medication class does Glyburide belong to?

    <p>Antidiabetic (Sulfonylureas)</p> Signup and view all the answers

    What is one mechanism of action for Glyburide?

    <p>Stimulates insulin synthesis and release from beta cells in pancreatic islets</p> Signup and view all the answers

    Name one drug that may decrease the effects of Glyburide.

    <p>Rifampin</p> Signup and view all the answers

    What are some possible side effects of Glyburide?

    <p>All of the above</p> Signup and view all the answers

    Which of the following is a contraindication for using Glyburide?

    <p>All of the above</p> Signup and view all the answers

    Patients should store Glyburide in a ______.

    <p>cool dry place away from sunlight and children</p> Signup and view all the answers

    What should a patient do if they miss a dose of Glyburide?

    <p>Take it as soon as possible, unless it's close to the next dose.</p> Signup and view all the answers

    What should patients avoid to ensure the optimal effect of Glyburide?

    <p>Excessive use of alcohol</p> Signup and view all the answers

    What signs of hypoglycemia should patients be aware of when taking Glyburide?

    <p>Sweating, tremor, blurred vision, weakness, hunger, confusion</p> Signup and view all the answers

    Study Notes

    Brand Names

    • Micronase and Diabeta are the brand names for Glyburide.

    Generic Name

    • Glyburide is the generic name for the medication.

    Indications

    • Used as an adjunct to diet for treating non-insulin dependent, stable or maturity onset type of mild to moderately severe diabetes mellitus.
    • No transition period is required when switching from most other hypoglycemics.

    Dosing Recommendations

    • Typical initial dose ranges between 1.25 to 5 mg, administered with breakfast.
    • Normal dosage is 2.5 to 5 mg, taken once or twice daily.
    • Maximum recommended daily dose is 20 mg.

    Available Strengths and Dosage Forms

    • Glyburide is available in tablet form with strengths of 1.25 mg, 2.5 mg, and 5.0 mg.

    Medication Class

    • Glyburide is classified as an antidiabetic medication, specifically within the sulfonylureas class.

    Pharmacology (Mechanism of Action)

    • Promotes insulin synthesis and release from the beta cells in pancreatic islets.
    • May enhance the binding between insulin and its receptors and increase the quantity of insulin receptors.

    Drug Interactions

    • The effects of Glyburide may be reduced by rifampin.

    Side Effects/Adverse Effects

    • Common side effects include nausea, diarrhea, heartburn, pruritus, and urticaria.
    • Mild hypoglycemic reactions are possible but rare, with the frequency of occurrence not clearly defined.

    Contraindications

    • Not recommended for juvenile, unstable, or complicated diabetes mellitus when used as sole therapy.
    • Contraindicated in diabetic ketoacidosis (with or without coma) and severe renal, hepatic, or thyroid dysfunction.
    • May need to be discontinued in cases of severe burns, infections, or trauma, switching to insulin instead.

    Patient Counseling Tips

    • Store Glyburide in a cool, dry place away from sunlight and children's reach.
    • If a dose is missed, take it as soon as possible; skip the dose if closer to the next scheduled time. Avoid doubling doses.
    • Seek medical advice if side effects are severe or persistent.
    • Take the medication with breakfast or the first main meal for best absorption.
    • Adherence to prescribed diet and medication schedule is crucial for optimal effectiveness.
    • Limit alcohol consumption and be aware of hypoglycemia signs, including sweating, tremors, blurred vision, weakness, hunger, and confusion. Treat with oral glucose or consult a physician if symptoms occur.

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    Description

    Test your knowledge of Glyburide with these flashcards. Explore key terms such as brand names, generic forms, indications, and dosing. Perfect for students or healthcare professionals looking to enhance their understanding of this essential medication.

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