Glucolisis y Respiración Anaeróbica

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6 Questions

¿Cuál es el resultado neto de la glucolisis?

1 glucosa → 2 piruvato + 2 ATP + 2 NADH

¿Cuál es la función de la hexoquinasa en la glucolisis?

Inhibir la glucólisis cuando la glucosa-6-fosfato está presente

¿Cuántos ATP se producen durante la glucolisis?

2 ATP

¿Qué sucede con el piruvato durante la respiración anaeróbica?

Se convierte en lactato o etanol

¿Cuál es la función del NADH en la glucolisis?

Transportar electrones en la cadena de transporte de electrones

¿Cuál es la diferencia entre la respiración aeróbica y anaeróbica en cuanto a la producción de ATP?

La respiración anaeróbica produce 2 ATP y la respiración aeróbica produce 36-38 ATP

Study Notes

Glucolysis

Glycolytic Pathway

  • Glucolysis is a metabolic pathway that converts glucose (a 6-carbon sugar) into pyruvate (a 3-carbon compound)
  • The pathway consists of 10 enzyme-catalyzed reactions
  • Occurs in the cytosol of cells
  • Net result: 1 glucose molecule → 2 pyruvate molecules + 2 ATP molecules + 2 NADH molecules

ATP Production

  • Glucolysis produces 2 ATP molecules through substrate-level phosphorylation
  • ATP is generated through the conversion of 1,3-bisphosphoglycerate to 3-phosphoglycerate
  • Additional ATP molecules can be generated during the electron transport chain in the mitochondria

Regulation of Glucolysis

  • Glucolysis is regulated by feedback inhibition and allosteric control
  • Key regulatory enzymes:
    • Hexokinase (inhibited by glucose-6-phosphate)
    • Phosphofructokinase (activated by fructose-2,6-bisphosphate and inhibited by ATP and citrate)
    • Pyruvate kinase (activated by fructose-1,6-bisphosphate and inhibited by ATP and alanine)

NADH and FADH2

  • NADH (nicotinamide adenine dinucleotide) is a high-energy electron carrier produced during glucolysis
  • NADH is used to generate ATP in the electron transport chain
  • FADH2 (flavin adenine dinucleotide) is not produced during glucolysis, but is involved in the electron transport chain

Anaerobic Respiration

  • Anaerobic respiration occurs in the absence of oxygen
  • Glucolysis is the only stage of cellular respiration that occurs during anaerobic respiration
  • Pyruvate is converted into lactate or ethanol, depending on the organism
  • Anaerobic respiration produces 2 ATP molecules per glucose molecule, compared to 36-38 ATP molecules during aerobic respiration

Aprende sobre el camino metabólico de la glucólisis, su regulación, producción de ATP y NADH, y su relación con la respiración anaeróbica.

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