Glomerular Filtration Rate Quiz
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Questions and Answers

What does the glomerular filtration rate (GFR) measure?

  • Plasma ultrafiltration rate
  • Body surface area
  • Renal excretory function (correct)
  • Serum creatinine production
  • How is the glomerular filtration rate (GFR) usually expressed?

  • 150 ± 25mL/min/1.73m2 (correct)
  • 200 ± 30mL/min/1.73m2
  • 250 ± 50mL/min/1.73m2
  • 100 ± 20mL/min/1.73m2
  • Which compound is most widely used in clinical practice to indirectly assess GFR?

  • Serum albumin
  • Urea
  • Serum creatinine (correct)
  • Glucose
  • What are the most widely used equations to estimate GFR from serum creatinine measurements?

    <p>Modification of Diet in Renal Disease (MDRD) and Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI)</p> Signup and view all the answers

    What has increased recognition of moderate kidney damage and encouraged early deployment of protective therapies?

    <p>Routine reporting of estimated GFR (eGFR) by laboratories</p> Signup and view all the answers

    Which component is the GFR proportionate to?

    <p>Body size</p> Signup and view all the answers

    Study Notes

    Glomerular Filtration Rate (GFR)

    • GFR measures the flow rate of fluid filtered through the glomeruli of the kidney.

    Unit of Measurement

    • GFR is usually expressed in milliliters per minute (mL/min).

    Clinical Assessment of GFR

    • Creatinine is the compound most widely used in clinical practice to indirectly assess GFR.

    Estimating GFR from Serum Creatinine

    • The most widely used equations to estimate GFR from serum creatinine measurements are the Cockcroft-Gault equation and the Modification of Diet in Renal Disease (MDRD) equation.

    Impact on Kidney Disease Management

    • Increased recognition of moderate kidney damage has encouraged early deployment of protective therapies.

    Physiological Correlation

    • GFR is proportionate to the surface area of the glomerular capillaries.

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    Description

    Test your knowledge about the glomerular filtration rate (GFR) and its significance in measuring renal excretory function. This quiz covers the assessment methods and reference values associated with GFR.

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