Glaucoma Overview
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Questions and Answers

What is the main cause of glaucoma?

Abnormally high intraocular pressure

What is the mechanism of action of topical beta blockers in treating glaucoma?

Blocks β1 and β2 receptors on the ciliary epithelium, inhibits cAMP synthesis, and decreases aqueous humor production

What distinguishes open-angle glaucoma from narrow-angle glaucoma?

Open-angle glaucoma has a normal appearance of the angle between iris and cornea, while narrow-angle glaucoma has an obstructed drainage angle by the root of the iris.

Which drug is considered the first-line therapy for glaucoma treatment?

<p>Topical beta blockers</p> Signup and view all the answers

How does Timolol differ from other beta blockers in glaucoma treatment?

<p>Timolol crosses the cornea more effectively than other beta blockers.</p> Signup and view all the answers

What are the common ocular side effects of topical beta blockers?

<p>Burning and decreased corneal sensation</p> Signup and view all the answers

What is the mechanism of action of alpha receptor agonists in treating glaucoma?

<p>Alpha receptor agonists decrease the rate of production of aqueous humor by constricting arteries and reducing blood flow to the ciliary body.</p> Signup and view all the answers

Name one side effect of prostaglandin agonists used in glaucoma treatment.

<p>One side effect is the darkening of the eye due to an increase in pigmentation in the iris.</p> Signup and view all the answers

How do carbonic anhydrase inhibitors like Acetazolamide work in the treatment of glaucoma?

<p>Carbonic anhydrase inhibitors block ciliary carbonic anhydrase activity, reducing aqueous formation from the ciliary body.</p> Signup and view all the answers

What are the primary side effects associated with the use of alpha receptor agonists in glaucoma treatment?

<p>Primary side effects include burning, stinging, ocular pain, dryness, tearing, and eyelid erythema.</p> Signup and view all the answers

Which glaucoma medication has been shown to increase aqueous outflow by as much as 50%?

<p>Latanoprost</p> Signup and view all the answers

What are the notable side effects of carbonic anhydrase inhibitors like Dorzolamide?

<p>Notable side effects include nausea, vomiting, metallic taste in the mouth, and paresthesia of the fingers, toes, and perioral area.</p> Signup and view all the answers

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