Germ Cell Tumors in Pediatrics
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Germ Cell Tumors in Pediatrics

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Questions and Answers

What is the primary treatment approach for intracranial germ cell tumors?

  • Chemotherapy
  • Hormone therapy
  • Surgery
  • Radiotherapy (correct)

    • What is the characteristic feature of sacrococcygeal teratomas?

  • Arises from mesodermal germ layer
  • Contains derivatives of the three embryonic germ layers (correct)
  • Most common in adults
  • Usually malignant

    • What is the most common solid tumor in the neonate?

  • Wilms tumor
  • Neuroblastoma
  • Retinoblastoma
  • Sacrococcygeal teratoma (correct)

    • What is the location of sacrococcygeal teratomas?

    <p>Tip of the coccyx</p> Signup and view all the answers

    When is a more toxic treatment regimen typically used?

    <p>For recurrent tumors</p> Signup and view all the answers

    What is the primary goal of liver resection in the treatment of congenital tumors?

    <p>To completely remove the tumor and prevent recurrence</p> Signup and view all the answers

    Which of the following tumors is known for its unpredictable behavior?

    <p>Neuroblastoma</p> Signup and view all the answers

    In pediatric oncology, what is the primary indication for liver transplantation?

    <p>All of the above</p> Signup and view all the answers

    What is the primary role of tumor markers in the diagnosis of congenital tumors?

    <p>To diagnose the tumor type</p> Signup and view all the answers

    What is the primary treatment option for sacrococcygeal tumors?

    <p>Surgical resection</p> Signup and view all the answers

    Which of the following procedures is NOT used for biopsy in neuroblastoma?

    <p>Mammography</p> Signup and view all the answers

    What is the Greek origin of the word 'teratoma'?

    <p>Teratos meaning monster</p> Signup and view all the answers

    What is a potential complication of neuroblastoma treatment?

    <p>Renal ischemia</p> Signup and view all the answers

    Which of the following is a minimally invasive procedure used for biopsy in neuroblastoma?

    <p>Laparoscopy</p> Signup and view all the answers

    What is a potential postsurgical complication of neuroblastoma treatment?

    <p>Chylous ascites</p> Signup and view all the answers

    Study Notes

    Germ Cell Tumors (GCTs)

    • A more toxic regimen is reserved for recurrence.
    • Radiotherapy is the mainstay for intracranial GCTs.

    Sacrococygeal Teratomas (SCT)

    • A congenital tumor containing derivatives of the three embryonic germ layers.
    • Arises at the tip of the coccyx.
    • The most common solid tumor in the neonate.

    Hepatoblastoma

    • Unresectable primary, multifocal tumors may be treated with:
      • Liver resection.
      • Liver transplantation.

    Neuroblastoma

    • An enigmatic embryonal tumor arising from neuroblasts with somewhat unpredictable behavior.

    Neuroblastoma Treatment

    • Biopsy methods:
      • Laparotomy or thoracotomy with classical open biopsy.
      • Laparoscopy or thoracoscopy with biopsy.
      • CT/USG-guided true-cut biopsy.
      • Fine needle aspiration.
    • Surgery may be performed.

    Neuroblastoma Complications

    • Hemorrhage.
    • Renal ischemia.
    • Intestinal ischemia.
    • Prolonged ileus, bowel obstruction, intussusception.
    • Chylous ascites.
    • Vascular injuries with consequent morbidity.

    Teratomas

    • Derived from the Greek words "teratos" meaning monster and "onkoma" meaning swelling.

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    Description

    This quiz covers the diagnosis and treatment of germ cell tumors in pediatrics, including sacrococygeal teratomas and intracranial GCTs.

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