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Pharmacology Mid Term

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Questions and Answers

Which of the following is NOT a potential cause of decreased lower esophageal sphincter (LES) pressure in gastroesophageal reflux disease (GERD)?

Excessive physical activity (correct)
Increased intraabdominal pressure
Spontaneous relaxation
Decreased LES tone

Which of the following activities can cause transient spontaneous relaxation of the LES in GERD?

Vomiting
Straining
Belching
All of the above (correct)

Which of the following is NOT a symptom of GERD?

Typical symptoms
Alarm symptoms
Epigastric pain (correct)
Atypical symptoms

What is the relationship between age and the incidence of GERD complications?

The incidence of complications increases with age (C) Signup and view all the answers

Which of the following is NOT a recommended nonpharmacologic intervention for GERD?

Taking antacids regularly (D) Signup and view all the answers

Which of the following is NOT a cause of peptic ulcer disease?

Increased hydrochloric acid (HCl) secretion (B) Signup and view all the answers

What is the main mechanism of action of H2-receptor antagonists in the treatment of peptic ulcer?

Reducing secretion of gastric acid (A) Signup and view all the answers

Which of the following is NOT a potential side effect of pharmacological treatment for peptic ulcer?

Increased appetite (D) Signup and view all the answers

Which drug classification is known for inhibiting the proton pump and reducing gastric acid secretion?

Proton pump inhibitors (A) Signup and view all the answers

What is the primary bacterial factor associated with the development of peptic ulcer disease?

Gram-negative Helicobacter pylori (B) Signup and view all the answers