8 Questions
What is the primary purpose of a genome-wide association study (GWAS)?
b) To analyze the entire genome for associations between genetic variations and traits or diseases.
What is the main advantage of imputing additional SNPs in a genome-wide association study?
b) It increases the statistical power of the study.
Which statistical test is commonly used to analyze the association between genetic variants and traits in a genome-wide association study?
c) Logistic regression
What is the purpose of interpreting findings in a genome-wide association study?
b) To identify potential therapeutic targets.
Which step of a genome-wide association study involves identifying specific genetic variations in each individual's DNA sample?
b) Hybridizing DNA to the array
In a genome-wide association study, what is the significance level typically used to determine whether an association between a genetic variant and a trait is statistically significant?
a) p < 0.05
What is the primary limitation of genome-wide association studies?
c) They may miss associations with rare genetic variants or gene-environment interactions.
What is the function of genotyping arrays in a genome-wide association study?
b) To identify specific genetic variations in each participant's DNA.
A genome-wide association study (GWAS) is a research approach used to identify genetic variants associated with a particular disease or trait. What is the primary purpose of a GWAS?
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