Genetics with Fruit Flies

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Questions and Answers

What was the primary model organism used by Thomas Hunt Morgan in his genetic experiments, and what key characteristic made them particularly advantageous for his research?

  • Fruit flies (Drosophila), because of their short life cycle and easily observable traits. (correct)
  • Pea plants, due to their rapid growth and ease of cultivation.
  • Bacteria, due to their simple genetic structure.
  • Mice, for their genetic similarity to humans.

What initial observation sparked a deeper investigation into eye color inheritance in Morgan's fruit fly experiments, and how did the first generation of offspring inform his understanding of dominance?

  • A white-eyed male crossed with a red-eyed female produced all red-eyed offspring, signifying red eye dominance. (correct)
  • A mix of red-eyed and white-eyed offspring was observed in the first generation, demonstrating incomplete dominance.
  • A red-eyed male crossed with a white-eyed female yielded all white-eyed offspring, indicating white eye dominance.
  • Both male and female parent flies with red eyes produced some white-eyed offspring, suggesting a complex inheritance pattern.

In Morgan's fruit fly experiments, through which lineage was the expression of white eyes passed down through to which generation?

  • Through both male and female offspring in third generation only
  • Randomly, with no discernible pattern of inheritance.
  • The female lineage, appearing in the first generation.
  • Equally through both male and female lineages in every generation.
  • The male lineage, reappearing in the second generation. (correct)

What groundbreaking discovery did Hermann Joseph Muller make in the field of genetics, and how did he achieve this?

<p>He induced hereditary changes in organisms with X-rays. (B)</p> Signup and view all the answers

When did Hermann Joseph Muller receive his PhD, from which University, and where did he conduct his research on genetic mutations for 12 years?

<p>PhD in 1916 from Columbia University, researched at University of Texas for 12 years. (C)</p> Signup and view all the answers

During which decade did Hermann Joseph Muller carry out his experiments using X-rays to induce mutations, and what was the wider impact of these findings?

<p>1920s, raised awareness about the dangers of radiation exposure to humans. (B)</p> Signup and view all the answers

How did the observation of white-eyed flies differ across offspring generations, and what genetic principle did it support?

<p>White eye trait reappeared in the second generation primarily in the males, confirming sex-linked recessive inheritance. (C)</p> Signup and view all the answers

Beyond eye color, what broader contribution did Morgan's fruit fly experiments make to the understanding of genetics?

<p>They proved that genes are located on chromosomes. (B)</p> Signup and view all the answers

What was Thomas Hunt Morgan's perspective on the work of geneticists, reflecting on their dedication and potential?

<p>He believed that geneticists faced tedious work yet held optimistic views about their field's future. (A)</p> Signup and view all the answers

Flashcards

Thomas Hunt Morgan

A geneticist known for his work with fruit flies and inheritance.

Drosophila

A genus of small fruit flies used in genetic experiments.

Dominant Trait

A trait that masks the expression of a recessive trait in offspring.

Recessive Trait

A trait that is masked by a dominant trait and only shows when two alleles are present.

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White-eyed trait

A recessive trait discovered in Morgan's fruit fly experiments.

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Hermann Joseph Muller

A geneticist who received a Nobel Prize for work on mutations and radiation effects.

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X-ray mutations

Genetic changes induced through exposure to X-rays.

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Gene inheritance

The process by which traits are passed from parents to offspring.

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Chromosome analysis

The study of chromosomes to understand genetic variations and inheritance.

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Study Notes

Geneticists and Fruit Flies

  • Geneticists, like Thomas Hunt Morgan, studied fruit flies to understand heredity
  • Morgan used millions of fruit flies, analyzing offspring variations
  • Morgan discovered inheritable traits and how they are passed through generations

Drosophila Research

  • Morgan's work used Drosophila melanogaster (fruit flies)
  • Fruit flies were ideal subjects due to displayed traits, small chromosomes, fast reproduction and large numbers

Discovering Inheritance

  • White-eyed male fruit flies bred with red-eyed females produced red-eyed offspring
  • Subsequent breeding showed a 1:4 ratio for white-eyed offspring in the second generation
  • This indicated white eye color was recessive compared to dominant red eye color

Herman Joseph Muller

  • A notable US geneticist researched induced genetic mutations
  • He earned a degree and a Nobel Prize for his work on inducing mutations with X-rays.
  • Investigated genetic mutations in flies with X-rays
  • He showed how radiation could induce mutations, which became an important finding in the context of the long-term dangers of human exposure to radiation.
  • Campaigned for radiation controls, highlighting risks from nuclear weapons.

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