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Questions and Answers
What is the primary function of a gene?
What is the primary function of a gene?
What results from a base substitution mutation?
What results from a base substitution mutation?
Where do alleles of the same gene occupy on chromosomes?
Where do alleles of the same gene occupy on chromosomes?
What characterizes a genome?
What characterizes a genome?
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What causes sickle cell anaemia?
What causes sickle cell anaemia?
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What is factor IX related to in the context of genetic modifications?
What is factor IX related to in the context of genetic modifications?
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What is a potential benefit of genetically modified (GM) crops?
What is a potential benefit of genetically modified (GM) crops?
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What is one of the concerns regarding the use of GMOs in agriculture?
What is one of the concerns regarding the use of GMOs in agriculture?
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How might genetic modifications improve livestock production?
How might genetic modifications improve livestock production?
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What could be a consequence of gene crossing among different species?
What could be a consequence of gene crossing among different species?
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What is the genotype for Type O blood?
What is the genotype for Type O blood?
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What is genetic modification primarily used for?
What is genetic modification primarily used for?
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Which of the following is an example of a transgenic plant?
Which of the following is an example of a transgenic plant?
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What does gene transfer involve?
What does gene transfer involve?
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Which characteristic did the genetically modified rice (yellow rice) aim to improve?
Which characteristic did the genetically modified rice (yellow rice) aim to improve?
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What is a benefit claimed by proponents of genetically modified foods?
What is a benefit claimed by proponents of genetically modified foods?
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Which of the following organisms had a gene transferred to create Bt-corn?
Which of the following organisms had a gene transferred to create Bt-corn?
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Which statement about genetic engineering is true?
Which statement about genetic engineering is true?
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What does the term 'genotype' refer to in genetics?
What does the term 'genotype' refer to in genetics?
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Which of the following correctly describes a dominant allele?
Which of the following correctly describes a dominant allele?
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In a genetic cross between tall and short plants, what is the expected phenotype of the F1 generation?
In a genetic cross between tall and short plants, what is the expected phenotype of the F1 generation?
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Which of the following is a characteristic of codominant alleles?
Which of the following is a characteristic of codominant alleles?
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What is the significance of Gregor Mendel's use of artificial pollination in his experiments?
What is the significance of Gregor Mendel's use of artificial pollination in his experiments?
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What does it mean for an organism to be homozygous?
What does it mean for an organism to be homozygous?
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Which term refers to the specific location of a gene on a chromosome?
Which term refers to the specific location of a gene on a chromosome?
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What is one of the four possible ABO blood type phenotypes in humans?
What is one of the four possible ABO blood type phenotypes in humans?
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Study Notes
Genes
- A gene is a heritable factor that influences a specific characteristic.
- A gene occupies a specific position on a chromosome.
- Genes are organized into chromosomes.
- Some genes have more than one form (alleles).
- An allele is a specific form of a gene differing from other alleles by one or a few bases.
- Alleles of the same gene occupy a corresponding place (locus) on each chromosome.
- Genome is the complete set of an organism's base sequences.
Chromosomes
- Chromosomes are bundles of long strands of DNA.
Mutations
- A mutation is a random, rare change in genetic material.
- A mutation can include changes in the sequence of bases.
- A base substitution mutation occurs when one base is substituted for another.
- Changing one base can result in a different amino acid being placed in the polypeptide chain.
- A mutation can have little or no effect on an organism or have a major influence on their physical characteristics.
- Sickle cell anemia is caused by a base substitution mutation in the gene that creates hemoglobin for red blood cells. This mutation changes the shape of the hemoglobin molecule and the red blood cell.
Theoretical Genetics
- Gregor Mendel, an Austrian monk, published results of his experiments with garden peas in 1865.
- Mendel referred to "factors" rather than "genes".
- Mendel used artificial pollination in his experiments.
- Mendel concluded that tall plants crossed with short plants resulted in tall plants.
- Mendel also concluded that tall plants crossed with other tall plants resulted in some short plants.
Key Terminology
- Genotype is the symbolic representation of a pair of alleles possessed by an organism (e.g., Bb, GG, Ll).
- Phenotype is the characteristics or traits of an organism (e.g., tall, yellow flowers, black fur).
- Dominant allele is always expressed in the phenotype and has the same effect whether paired with the same allele or a different one.
- Recessive allele is expressed only when present in the homozygous state.
- Codominant alleles are pairs of alleles that both affect the phenotype when present in a heterozygote.
- Locus is the specific position of a gene on homologous chromosomes.
- Homozygous is having two identical alleles of a gene (e.g., AA and aa).
- Heterozygous is having two different alleles of a gene (e.g., Aa).
Monohybrid Genetic Cross
- A monohybrid genetic cross involves crossing organisms that differ in only one trait.
Multiple Alleles
- ABO blood type system in humans is an example of multiple alleles with four possible phenotypes: A, B, AB, and O.
- There are three alleles of the gene for ABO blood type: IA, IB, and i.
- These three alleles can produce six different genotypes.
Genetic Modification
- Genetic modification is a technique to change the characteristics of an organism by transferring a piece of DNA from one organism to a different organism.
- Gene transfer involves taking a gene from a donor organism and placing it in a host organism.
Genetically Modified Organisms
- A genetically modified organism (GMO) is an organism that has had an artificial genetic change using genetic engineering techniques.
- Arctic fish cold resistant gene has been transferred to tomatoes to make them resistant to cold and frost.
- Gene for pest-killing toxin has been transferred from soil bacteria (Bacillus thuringiensis) to corn to form Bt-corn.
Transgenic Plants (Crops)
- Transgenic plants have had genes removed or inserted to make them more desirable.
- "Flavr Savr" tomato was genetically modified to delay ripening and rotting, making it stay fresher for longer.
- Some believe GMOs could help solve world hunger by allowing farmers to grow food in difficult conditions.
- Genetically modified rice (yellow rice) was engineered to produce beta carotene in the rice grains to prevent vitamin A deficiency.
Transgenic Animals
- Transgenic animals can be used to produce substances for medical treatment, like factor IX.
- Transgenic sheep can be used to produce factor IX protein in their milk.
- Future genetic modifications could include inserting genes to make animals more resistant to parasites or producing wool in specific colors.
Genetic Engineering: Good or Bad?
- GMOs have potential benefits, promises, and hopes for the future including:
- GM crops can improve food production.
- GM crops that produce their own pest-control substances can be beneficial to the environment by reducing the need for chemical pesticides.
- GMOs can be used to produce rare proteins for medications or vaccines, which could be less costly and produce less pollution in the long run.
- Farmers can be more in control of what crops or livestock they produce.
- GM plants can reduce hunger by allowing farmers to use pest/drought-resistant crops in developing nations.
Harmful Effects, Dangers, and Fears
- Concerns about GMOs include:
- No one knows the long-term effects of GMOs in the wild.
- Genes could cross species and have unpredictable consequences.
- Bt-crops could be harmful to humans.
- Risks for allergies exist.
- A small number of corporations could control large portions of the human food supply.
- Proliferation of GMOs could lead to a decrease in biodiversity.
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Description
Test your knowledge on the fundamentals of genetics, including genes, chromosomes, and mutations. This quiz covers key concepts such as allele variation, genome structure, and the impacts of mutations. Perfect for students looking to reinforce their understanding of genetic principles.