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Questions and Answers
What inheritance pattern does a dihybrid cross illustrate?
What inheritance pattern does a dihybrid cross illustrate?
What is the expected phenotypic ratio from a typical monohybrid cross involving complete dominance?
What is the expected phenotypic ratio from a typical monohybrid cross involving complete dominance?
In a dihybrid cross where one parent is WW and the other is ww, what is the dominant phenotype expected in the offspring?
In a dihybrid cross where one parent is WW and the other is ww, what is the dominant phenotype expected in the offspring?
What does a phenotypic ratio of 3:1 represent in a genetics cross?
What does a phenotypic ratio of 3:1 represent in a genetics cross?
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In non-Mendelian inheritance, which of the following does NOT typically occur?
In non-Mendelian inheritance, which of the following does NOT typically occur?
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What does the gene fibrillin primarily contribute to in the body?
What does the gene fibrillin primarily contribute to in the body?
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What is the genetic basis of Sickle Cell Anemia?
What is the genetic basis of Sickle Cell Anemia?
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In human genetics, what does the 23rd pair of chromosomes determine?
In human genetics, what does the 23rd pair of chromosomes determine?
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What term is used to describe the inheritance pattern where traits are influenced by multiple genes?
What term is used to describe the inheritance pattern where traits are influenced by multiple genes?
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What anatomical structures are directly affected by a faulty fibrillin gene?
What anatomical structures are directly affected by a faulty fibrillin gene?
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What does the ABCC11 gene influence regarding body odor?
What does the ABCC11 gene influence regarding body odor?
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Which principle is NOT part of Mendel’s Laws of Inheritance?
Which principle is NOT part of Mendel’s Laws of Inheritance?
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In which section is the concept of 'Nature vs. Nurture' discussed?
In which section is the concept of 'Nature vs. Nurture' discussed?
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What is typically the focus of pedigree analysis?
What is typically the focus of pedigree analysis?
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Which type of inheritance is discussed at the end of the outline?
Which type of inheritance is discussed at the end of the outline?
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What is a primary focus in the section on chromosomal abnormalities?
What is a primary focus in the section on chromosomal abnormalities?
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What is emphasized in the pledge regarding academic integrity?
What is emphasized in the pledge regarding academic integrity?
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Who are the authors mentioned for the Grade 12 reviewer handout?
Who are the authors mentioned for the Grade 12 reviewer handout?
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What is an example of codominance as described in the content?
What is an example of codominance as described in the content?
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According to Mendel's laws, what does the law of dominance state?
According to Mendel's laws, what does the law of dominance state?
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What is pleiotropy as defined in the content?
What is pleiotropy as defined in the content?
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In a heterozygous organism with one dominant and one recessive allele, which allele will be expressed?
In a heterozygous organism with one dominant and one recessive allele, which allele will be expressed?
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What ratio represents the genotype and phenotype distribution in one of the described traits?
What ratio represents the genotype and phenotype distribution in one of the described traits?
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Which of the following is true regarding the law of segregation?
Which of the following is true regarding the law of segregation?
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Which blood type represents individuals with both alleles expressed equally?
Which blood type represents individuals with both alleles expressed equally?
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What genetic condition is an example of pleiotropy?
What genetic condition is an example of pleiotropy?
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What describes the phenotype produced from a heterozygous cross of two homozygous plants in incomplete dominance?
What describes the phenotype produced from a heterozygous cross of two homozygous plants in incomplete dominance?
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What occurs in codominance with respect to alleles?
What occurs in codominance with respect to alleles?
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If a homozygous red snapdragon is crossed with a homozygous white snapdragon, the offspring will be?
If a homozygous red snapdragon is crossed with a homozygous white snapdragon, the offspring will be?
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In a cross of a black-feathered chicken and a white-feathered chicken exhibiting codominance, what would the offspring look like?
In a cross of a black-feathered chicken and a white-feathered chicken exhibiting codominance, what would the offspring look like?
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Which of the following statements about incomplete dominance is correct?
Which of the following statements about incomplete dominance is correct?
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What is true regarding the genotypes of the offspring from a cross of two codominant feathered chickens?
What is true regarding the genotypes of the offspring from a cross of two codominant feathered chickens?
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In the context of genetic dominance, which trait can be observed in codominance?
In the context of genetic dominance, which trait can be observed in codominance?
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If incomplete dominance were to occur in a population of plants, which would most likely be the result?
If incomplete dominance were to occur in a population of plants, which would most likely be the result?
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Who is most likely to exhibit severe physical and intellectual abnormalities due to an X-linked recessive disorder?
Who is most likely to exhibit severe physical and intellectual abnormalities due to an X-linked recessive disorder?
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What is a common characteristic of X-linked recessive disorders?
What is a common characteristic of X-linked recessive disorders?
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Which condition is characterized by an extra copy of chromosome 21?
Which condition is characterized by an extra copy of chromosome 21?
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What is a common consequence of Klinefelter Syndrome in males?
What is a common consequence of Klinefelter Syndrome in males?
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What describes Turner Syndrome in females?
What describes Turner Syndrome in females?
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Which of the following abnormalities is less likely to occur in females with an X-linked recessive disorder?
Which of the following abnormalities is less likely to occur in females with an X-linked recessive disorder?
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What is the primary factor that determines the severity of Down Syndrome?
What is the primary factor that determines the severity of Down Syndrome?
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Why do most infants with severe complications from X-linked recessive disorders not survive beyond their first year?
Why do most infants with severe complications from X-linked recessive disorders not survive beyond their first year?
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What distinguishes Klinefelter Syndrome from other genetic disorders?
What distinguishes Klinefelter Syndrome from other genetic disorders?
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Which abnormality is NOT commonly associated with Down Syndrome?
Which abnormality is NOT commonly associated with Down Syndrome?
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Study Notes
AUF Honor Code
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- Students agree to not receive or give unauthorized assistance
- Students commit to observing scholarly and intellectual standards
- Students commit to proper citation of sources and appropriate data collection and use
Reminder
- The lecture material is provided to guide students in preparation for upcoming activities, quizzes, and exams
- Students are strongly encouraged to review course materials and resources provided by the school and teachers to improve their performance on assessments
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General Biology 2 - Lesson 1: Heredity and Patterns of Inheritance
Introduction
- Stink-Free Gene (ABCC11): A mutated gene that affects the secretion of odorants and their precursors from apocrine sweat glands (armpits)
- Heredity (Inheritance): The process of traits being passed from one generation to the next (parents to offspring)
- Genetics: The branch of science that studies heredity
Foundations of Heredity
- Gregor Mendel (1822-1884): Known as the "Father of Genetics"
- Mendel conducted breeding experiments with garden peas ( Pisum sativum) to study inheritance patterns
- Mendel's Laws of Inheritance (later details are given)
Garden Pea ( Pisum sativum)
- Easy to cultivate
- Short generation time
- Can be cross-pollinated by hand
- Exhibits clear and distinguishable traits
Genes, Traits, and Alleles
- Gene: Units in organisms that control the expression of traits
- Trait: Distinguishable characteristics
- Allele: Alternative forms of a gene (B=dominant, b=recessive)
Dominant vs. Recessive
- Dominant (B): The allele that masks the recessive allele. Expressed always.
- Recessive (b): An allele only expressed in the absence of the dominant allele
Homozygous vs. Heterozygous
- Homozygous: Describes an individual with the same allele of a gene on both homologous chromosomes
- Heterozygous: Describes an individual with different alleles for a gene on homologous chromosomes
Genotype and Phenotype
- Genotype: The genetic makeup of an organism; the set of alleles present in an individual's chromosomes.
- Phenotype: The observable physical traits expressed by an organism.
Breeding (Mating)- Punnett Square
- True-Breeding: Parents with certain traits consistently pass those traits to every offspring
- Punnett Square: A square diagram use to predict possible genetic outcomes of a cross-breeding experiment
Mendel's Laws of Inheritance
- (Details on the three laws are later explained in a more sophisticated manner)*
Inheritance Patterns (Non-Mendelian)
- Incomplete Dominance: One allele is not fully dominant over the other; the heterozygous phenotype is an intermediate blend of the homozygous phenotypes.
- Codominance: Both alleles are simultaneously expressed, resulting in a combined phenotypic expression.
- Pleiotropy: A single gene affecting multiple traits.
- Polygenic Inheritance: Multiple genes control the phenotype of an organism.
- Epistasis: Two or more genes contribute to a phenotype but one gene may overshadow the other contributing genes
Inheritance Patterns in Humans
- Autosomal Dominant: A single copy of a mutated gene (from one parent) is enough to cause the disorder in both sexes.
- Autosomal Recessive: Two copies of the mutated gene (from both parents) are needed to cause the disorder in both sexes
- X-linked Dominant: Affected fathers pass the trait to all daughters, no carriers.
- X-linked Recessive: Males are more frequently affected than females; mothers pass down to their sons
Chromosomal Abnormalities
- Polyploidy: Species with three or more sets of chromosomes
- Aneuploidy: Too many or too few copies of a particular chromosome (nondisjunction)
- Specific Syndrome Examples: (e.g., Down Syndrome, Patau Syndrome, Turner Syndrome, Klinefelter Syndrome, etc.)
Additional topics
- Types of genetic disorders
- Pedigree analysis
- Determining if traits are dominant or recessive
- Identifying if traits are sex-linked or autosomal
- Other diseases like Albinism, Tay-Sachs disease etc
- (Further details and explanations are given throughout the following pages)*
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Description
Test your knowledge on inheritance patterns in genetics with this quiz, including dihybrid and monohybrid crosses. You'll explore concepts like expected phenotypic ratios and dominant phenotypes. Ideal for students studying Mendelian and non-Mendelian genetics.