Genetics: Genes, DNA, and Chromosomes

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Questions and Answers

Which of the following accurately defines a gene?

  • The molecule that carries genetic code or information.
  • A section of DNA that codes for a particular protein. (correct)
  • A structure of DNA found in the nucleus of a cell.
  • The different forms of a particular protein.

What is the role of alleles in genetics?

  • To code for specific proteins within a cell.
  • To provide different versions of the same gene. (correct)
  • To carry the genetic code from one generation to the next.
  • To organise the structure of DNA in the nucleus.

Which scientist's work with X-ray diffraction significantly contributed to the discovery of DNA's double helix structure?

  • Gregor Mendel
  • James Watson
  • Francis Crick
  • Rosalind Franklin (correct)

What type of bond links the two strands of a DNA molecule together?

<p>Attraction of complementary base pairings. (C)</p> Signup and view all the answers

During DNA replication, a sequence on one strand reads 'ATC'. What would be the corresponding sequence on the complementary strand?

<p>TAG (C)</p> Signup and view all the answers

What defines homologous chromosomes?

<p>Chromosomes that have the same genes in the same loci (A)</p> Signup and view all the answers

If a DNA triplet code is AGC, what type of molecule is directly determined by this sequence?

<p>An amino acid (D)</p> Signup and view all the answers

Which of the following is the only source of new alleles and genetic variation within a species?

<p>Mutation (D)</p> Signup and view all the answers

A mutation in a skin cell is unlikely to have evolutionary consequences. Why?

<p>Mutations in body cells are not inheritable. (C)</p> Signup and view all the answers

Which type of point mutation results in a change to the reading frame of the genetic sequence?

<p>Deletion (B)</p> Signup and view all the answers

Cystic fibrosis is caused by a deletion of three bases in the CFTR gene. What is the immediate consequence of this mutation at the protein level?

<p>Deletion of one amino acid. (C)</p> Signup and view all the answers

In sickle cell anaemia, a point mutation in the HBB gene causes a single amino acid change that affects the shape of red blood cells. What type of point mutation is responsible for this?

<p>Substitution (A)</p> Signup and view all the answers

Why is sexual reproduction more beneficial than asexual reproduction in the long run for species survival?

<p>It allows for increased genetic variation. (D)</p> Signup and view all the answers

What is the purpose of meiosis?

<p>To produce 4 genetically unique gametes with half the number of chromosomes. (B)</p> Signup and view all the answers

What process during meiosis leads to the exchange of genetic material between homologous chromosomes?

<p>Crossing over (A)</p> Signup and view all the answers

How does independent assortment contribute to genetic variation?

<p>By randomly arranging homologous chromosomes during meiosis (A)</p> Signup and view all the answers

What is the definition of a gene pool?

<p>All the alleles available to a population. (B)</p> Signup and view all the answers

What effect does immigration have on the genetic variation of a population?

<p>Increases genetic variation by introducing new alleles. (D)</p> Signup and view all the answers

What is the role of 'VARPA' in the context of natural selection?

<p>It describes the process of natural selection. (D)</p> Signup and view all the answers

Why is variation within a population crucial for natural selection?

<p>It provides the raw material upon which selection can act. (C)</p> Signup and view all the answers

What is genetic drift?

<p>The change in allele frequencies due to random chance. (A)</p> Signup and view all the answers

Why does genetic drift have a more significant impact on smaller populations?

<p>Random events are more likely to alter allele frequencies significantly. (C)</p> Signup and view all the answers

What is the founder effect?

<p>When a small number of individuals establish a new, isolated population. (D)</p> Signup and view all the answers

How can the founder effect impact the genetic variation of a population?

<p>It can lead to a new population not representative of the original population. (B)</p> Signup and view all the answers

What is the bottleneck effect?

<p>The significant reduction because of an environmental event. (A)</p> Signup and view all the answers

How does the bottleneck effect affect the genetic variation of a species?

<p>Reduces genetic variation, potentially leading to loss or fixation of alleles. (A)</p> Signup and view all the answers

Even if a population recovers in size after experiencing a bottleneck effect, why might it still be vulnerable?

<p>The lack of genetic variation increases the risk of inbreeding and harmful mutations becoming more common. (A)</p> Signup and view all the answers

A population of butterflies exhibits two distinct wing patterns: vibrant orange and subdued brown. A sudden volcanic eruption darkens the surrounding landscape with ash. Over several generations, the proportion of brown butterflies increases significantly. Which evolutionary mechanism is MOST likely responsible for this shift in wing pattern frequency?

<p>Natural selection (A)</p> Signup and view all the answers

Imagine a scenario where a hurricane devastates a small island inhabited by a lizard population. Only a few lizards survive, and by chance, these survivors possess a set of rare traits not representative of the original population. What is the MOST accurate description of the long-term evolutionary consequence?

<p>Genetic drift, resulting in random fluctuations of allele frequencies unrelated to adaptive advantages. (D)</p> Signup and view all the answers

In a remote island population of birds, a single bird with a unique beak shape arrives from the mainland. This beak shape allows it to access a previously untapped food source, leading to enhanced survival and reproduction rates compared to the native birds. Decades later, nearly all birds on the island possess this novel beak shape. Which evolutionary mechanisms BEST explains this scenario?

<p>Gene flow followed by natural selection. (B)</p> Signup and view all the answers

A researcher is studying a plant population on a remote island. They observe that the plants exhibit a wide range of flower colors, but a fungal disease suddenly wipes out most of the plants with red flowers. Over time, the population recovers, but the prevalence of red flowers remains very low. Which combination of evolutionary mechanisms likely explains this scenario?

<p>The bottleneck effect and natural selection. (C)</p> Signup and view all the answers

What is the relationship between a gene and a protein?

<p>A gene is a section of DNA that codes for a specific protein. (B)</p> Signup and view all the answers

Which component is NOT part of a nucleotide?

<p>Amino acid (B)</p> Signup and view all the answers

What type of bond holds complementary base pairs together in a DNA molecule?

<p>Hydrogen bond (A)</p> Signup and view all the answers

What is the role of triplets in the genetic code?

<p>They code for specific amino acids. (A)</p> Signup and view all the answers

What is the immediate result of a change in the sequence of amino acids in a polypeptide chain?

<p>Change in the protein structure (D)</p> Signup and view all the answers

If a mutation occurs in a body cell, why isn't it inheritable?

<p>Body cells are not involved in reproduction. (A)</p> Signup and view all the answers

Which type of mutation has the least impact on the resulting protein sequence?

<p>Substitution (C)</p> Signup and view all the answers

If a substitution point mutation does not alter the amino acid sequence of the resulting protein. What is this known as?

<p>Silent mutation (B)</p> Signup and view all the answers

A mutation in a gene shifts the reading frame and introduces a premature stop codon. What type of mutation is this considered?

<p>Nonsense (B)</p> Signup and view all the answers

Why is sexual reproduction considered a source of genetic variation?

<p>It combines genetic material from two parents. (A)</p> Signup and view all the answers

What is the direct outcome of fertilization during sexual reproduction?

<p>Formation of a zygote (C)</p> Signup and view all the answers

How does crossing over contribute to genetic variation?

<p>By exchanging genetic material between homologous chromosomes. (C)</p> Signup and view all the answers

During which phase of meiosis does independent assortment occur?

<p>Metaphase I (A)</p> Signup and view all the answers

What is the significance of having half the number of chromosomes in gametes produced by meiosis?

<p>It ensures the zygote has the correct number of chromosomes after fertilization. (D)</p> Signup and view all the answers

Which field of biology specifically examines the allele frequencies within populations and how these change over time?

<p>Population genetics (D)</p> Signup and view all the answers

What is the term for the movement of alleles between different populations?

<p>Gene flow (C)</p> Signup and view all the answers

What is the difference between emigration and immigration?

<p>Emigration decreases the gene pool, while immigration increases it. (D)</p> Signup and view all the answers

What does 'VARPA' describe?

<p>The process of natural selection (C)</p> Signup and view all the answers

Within the VARPA framework, what is the role of 'selection pressure'?

<p>It is an environment factor the affects survival of an organism in its environment. (B)</p> Signup and view all the answers

What is the MOST likely consequence of a population having very limited genetic variation?

<p>Higher risk of extinction when faced with new challenges (C)</p> Signup and view all the answers

Which of the following describes genetic drift?

<p>Changes in allele frequencies due to random chance (D)</p> Signup and view all the answers

Why is genetic drift more pronounced in small populations?

<p>Random events have a larger impact on allele frequencies in small populations. (A)</p> Signup and view all the answers

What is the key characteristic of the founder effect?

<p>A small group establishes a new, isolated population. (B)</p> Signup and view all the answers

Why might a new population established by the founder effect have limited genetic variation?

<p>The founding individuals carry a random subset of the original population's alleles. (D)</p> Signup and view all the answers

Which scenario BEST describes the bottleneck effect?

<p>A population experiences a drastic reduction in size due to a natural disaster. (C)</p> Signup and view all the answers

How does the bottleneck effect potentially affect a species' ability to adapt to future environmental changes?

<p>It reduces genetic variation, limiting the potential for adaptation. (C)</p> Signup and view all the answers

A population of frogs is thriving in a stable wetland environment. A prolonged drought dramatically shrinks the wetland, leading to a significant reduction in the frog population. What is the MOST likely long-term consequence of this event?

<p>Reduced genetic diversity and increased vulnerability to diseases. (B)</p> Signup and view all the answers

In a population of wildflowers, some individuals produce fragrant flowers while others produce odorless flowers. Over several generations, the proportion of fragrant flowers decreases, while the proportion of odorless flowers increases. Which of the following scenarios is LEAST likely to explain the observed shift?

<p>A chance event eliminates most of the fragrant flowers, leading to a founder effect. (B)</p> Signup and view all the answers

In a population of fish. Larger fish are better at defending territory but are more visible to predators. Smaller fish are harder to see but struggle to compete for resources. Over time, the population exhibits a stable distribution of both large and small fish sizes. Which mechanism maintains the variation?

<p>Stabilizing selection (C)</p> Signup and view all the answers

A road construction project divides a population of rodents into two isolated groups. Over many generations, genetic differences accumulate between the two groups due to genetic drift and local adaptation. Eventually, when the road is removed, the two groups can no longer interbreed. Which of the following has occurred?

<p>Reproductive Isolation (B)</p> Signup and view all the answers

In a hypothetical scenario, a population of birds is subjected to strong directional selection favoring larger beak sizes due to a shift in the available food source towards larger seeds. After many generations, all birds in the population exhibit extremely large beaks. However, a sudden shift back to smaller seeds occurs. What is the MOST likely outcome?

<p>The bird population will likely face a population decline, possibly leading to extinction. (B)</p> Signup and view all the answers

Why is it essential to consider both genetic drift and natural selection when analyzing the evolution of small, isolated populations?

<p>Because the relative strength of genetic drift can overshadow adaptive evolution driven by natural selection in small populations. (D)</p> Signup and view all the answers

Considering the different mechanisms of evolution, which of these options will always result in adaptation?

<p>Natural selection (B)</p> Signup and view all the answers

How does understanding allele frequencies in a population help scientists?

<p>Predicting future evolutionary changes. (A)</p> Signup and view all the answers

Besides mutation, why is sexual reproduction important for promoting genetic variation?

<p>It shuffles alleles into new combinations. (B)</p> Signup and view all the answers

The total collection of genes in a population at any one time is known as what?

<p>Gene pool (C)</p> Signup and view all the answers

What happens in gene flow?

<p>Genes flow from one population to another (Immigration). (C)</p> Signup and view all the answers

According to 'VARPA', which option is genetically 'better suited' to the environment?

<p>The allele that reproduces more successfully. (A)</p> Signup and view all the answers

Imagine a scenario where a population of insects is exposed to a new pesticide. Initially, a small percentage of the population possesses a genetic mutation that confers resistance to the pesticide. After several generations of pesticide use, the vast majority of the insect population is now resistant. Which evolutionary mechanisms BEST explains this?

<p>Natural Selection (B)</p> Signup and view all the answers

Genetic drift does NOT depend on which factor?

<p>Natural Selection. (A)</p> Signup and view all the answers

What is the underlying theme of genetics?

<p>The study of the inheritance and variation of genes. (A)</p> Signup and view all the answers

If a population gains individuals, what is MOST likely to happen to genetic variation?

<p>Genetic variation is amplified. (D)</p> Signup and view all the answers

If there are little to no phenotypes better suited than others, and 'VARPA' never occurs, what is MOST likely to happen?

<p>The allele frequency will not change significantly. (A)</p> Signup and view all the answers

Flashcards

Genetics

The study of the variation and inheritance of genes.

DNA

Molecule carrying genetic code.

Gene

Section of DNA coding for a protein.

Alleles

Different forms of a gene.

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Chromosome

Organized structure of DNA in a cell's nucleus.

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Nucleotide

Repeated building block of DNA.

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Homologous Chromosomes

Pairs of chromosomes with the same genes.

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Genetic Code

Base sequence of DNA allowing proteins to be made.

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Genetic Variation

Differences in DNA among individuals.

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Mutation

Random, permanent change in DNA.

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Point Mutation

Mutation affecting only a few bases.

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Substitution

Base swapped with another.

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Deletion

Base is removed.

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Insertion

Base is added.

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Sexual Reproduction

Reproduction involving two parents.

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Asexual Reproduction

Reproduction involving one parent.

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Meiosis

Creates 4 genetically unique gametes.

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Crossing Over

Homologous chromosomes exchange DNA.

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Independent Assortment

Random arrangement of chromosomes.

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Population Genetics

Studies genetic variation within populations.

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Gene Pool

All alleles available to a population.

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Allele Frequency

Percentage of each allele in a population.

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Gene Flow

Transfer of genetic material between populations.

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Migration

Individuals move between populations.

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Natural Selection

Phenotypes that offer a survival advantage.

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Selection Pressure

Environmental factors affecting survival.

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Genetic Drift

Change in allele frequencies by chance.

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Founder Effect

Small group starts new, isolated population.

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Bottleneck Effect

Population size severely reduced.

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Study Notes

  • Genetics is the study of genes, trait inheritance, and variation.
  • DNA is the molecule carrying genetic information.
  • A gene is a DNA segment that codes for a specific protein/trait.
  • Alleles are different versions of the same gene.
  • A chromosome is an organized structure of DNA in the nucleus of a cell.
  • Individuals of the same species share identical genes, but have diverse alleles.
  • DNA has a double helix structure.
  • A nucleotide, consisting of deoxyribose sugar, phosphate, and a nitrogenous base, is the building block of DNA.
  • DNA strands are linked by complementary base pairings: Adenine (A) pairs with Thymine (T), and Cytosine (C) pairs with Guanine (G).
  • Photo 51 by Rosalind Franklin was critical to discovering DNA's double helix structure, revealing X-ray diffraction patterns.
  • Homologous chromosomes are chromosome pairs with the same genes.
  • Chromosomes replicate their DNA before dividing to form new cells.
  • Individuals inherit one copy of each chromosome pair from each parent.

Genetic Code

  • Refers to the DNA base sequence that dictates protein synthesis.
  • It is read in triplets (3 bases), each coding for a specific amino acid.
  • Amino acids are linked according to the base sequence to form proteins.
  • A protein is a long chain of amino acids folded into a specific shape.
  • The order of bases determines the specific protein produced.
  • The sequence of amino acids forms the primary protein structure (polypeptide chain).
  • Phenotype differences result from differences in protein structure.

Genetic Variation

  • Genetic variation means the differences in DNA among individuals within a population or species.
  • Mutation is the only source of new alleles and genetic variation.
  • Mutation is a random, permanent change in the DNA base sequence.
  • Mutations influence phenotype by altering the DNA base sequence, thereby changing how the genetic code is read and thus creating new alleles that code for different proteins.
  • Only mutations in gametes are inheritable; those in body cells are not.
  • Point mutation involves changes to one or a few bases within a DNA sequence, affecting one gene.
  • Types of point mutations:
    • Substitution: One base is swapped for another, affecting a single triplet.
    • Deletion: A base is removed, affecting multiple triplets and the reading frame.
    • Insertion: A base is added, affecting multiple triplets and the reading frame.
  • Cystic fibrosis is caused by a deletion point mutation of three bases in the CFTR gene.
  • Sickle cell anemia is caused by a substitution point mutation in the HBB gene.
  • Hemophilia is a bleeding disorder caused by a substitution point mutation on the X chromosome.
  • Sexual reproduction introduces variation through the combination of genes from two parents.
  • Asexual reproduction does not result in genetic variation.
  • Sexual reproduction offers an advantage, because genetic variation safeguards against environmental changes and diseases.
  • Fertilization mixes genetic information from two parents to form a zygote, increasing genetic variation.
  • Meiosis is a cell division process that produces 4 genetically unique gametes with half the number of chromosomes.
  • Meiosis produces variation through crossing over and independent assortment.
  • Crossing over involves homologous chromosomes exchanging DNA, creating new allele combinations.
  • Independent assortment involves the random arrangement of homologous chromosomes during meiosis, leading to new allele combinations.

Population Genetics

  • Population genetics is the study of genetic variation within populations and its changes over time.
  • A gene pool includes all alleles available in a population.
  • Allele frequency is the percentage of each allele in a population.
  • Gene flow is the transfer of genetic material from one population to another.
  • Migration is when individuals move between populations.
    • Immigration introduces new alleles, increasing genetic variation and the gene pool size.
    • Emigration removes alleles, decreasing genetic variation and the gene pool size.
  • Natural selection happens when certain phenotypes are more suited to the environment.
  • VARPA describes natural selection
    • Variation: Genetic variation exists in a population.
    • Advantageous Alleles: Some phenotypes are better suited to the environment.
    • Reproduction: Suited individuals survive and reproduce.
    • Passing On: They pass on favorable alleles to offspring.
    • Allele Frequency: Favorable allele frequency increases over generations.
  • Selection pressure refers to environmental factors that affect an organism's survival.
  • Variation is important for natural selection, as it ensures that some individuals with favorable alleles survive environmental changes, allowing the species to continue.
  • Natural selection increases the chances of future population survival, but a lack of variation can lead to extinction.
  • Genetic drift is the change in allele frequencies due to random chance, decreasing genetic diversity.
  • Genetic drift has a greater impact on smaller populations.

The Founder Effect

  • The founder effect happens when establishing of a new population occurs from a small number of individuals.
  • The founder effect reduces genetic variation in both the original and new populations.
  • The new population is usually not representative of the original population.

The Bottleneck Effect

  • The bottleneck effect happens when there is a significant reduction in population size.
  • The bottleneck effect significantly reduces genetic variation.
  • Reduced population size results in increased vulnerability to diseases.
  • Genetic drift leads to lost or fixed alleles, so the new gene pool is unrepresentative of the original one.
  • A lack of variation increases the risk of inbreeding and harmful mutations.

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