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Questions and Answers
Which of the following statements best describes meiotic drive?
Which of the following statements best describes meiotic drive?
Pleiotropy occurs when one gene affects multiple phenotypes.
Pleiotropy occurs when one gene affects multiple phenotypes.
True
What phenomenon describes genes that are inherited together due to their physical proximity on a chromosome?
What phenomenon describes genes that are inherited together due to their physical proximity on a chromosome?
Physical linkage
The ABO blood type system is an example of more than ______ alleles at a gene/locus.
The ABO blood type system is an example of more than ______ alleles at a gene/locus.
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Which term refers to the effect when a single allele causes one genetic disorder, but its dominance or recessiveness may vary depending on the phenotype examined?
Which term refers to the effect when a single allele causes one genetic disorder, but its dominance or recessiveness may vary depending on the phenotype examined?
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Alleles at different loci always assort independently.
Alleles at different loci always assort independently.
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Match the following terms with their correct definitions:
Match the following terms with their correct definitions:
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Name a rare but dominant allele that can cause a condition in humans.
Name a rare but dominant allele that can cause a condition in humans.
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What is the probability of producing red-flower offspring from the genotypes RR, Rr, or rR?
What is the probability of producing red-flower offspring from the genotypes RR, Rr, or rR?
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All offspring genotypes lead to the same phenotype.
All offspring genotypes lead to the same phenotype.
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What is the probability of obtaining the genotype AABb from a double heterozygote (AaBb) mating with an AaBB individual?
What is the probability of obtaining the genotype AABb from a double heterozygote (AaBb) mating with an AaBB individual?
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Mendel’s law of __________ dominance describes a scenario where a dominant trait is completely expressed over a recessive one.
Mendel’s law of __________ dominance describes a scenario where a dominant trait is completely expressed over a recessive one.
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Match the type of dominance with its description:
Match the type of dominance with its description:
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In a cross between Aa and Aa, what is the expected frequency of the homozygous recessive genotype?
In a cross between Aa and Aa, what is the expected frequency of the homozygous recessive genotype?
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Environmental factors can have no impact on genetic expression.
Environmental factors can have no impact on genetic expression.
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What is the Hardy-Weinberg principle used for?
What is the Hardy-Weinberg principle used for?
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What is the primary effect of epistasis in genetics?
What is the primary effect of epistasis in genetics?
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All traits are governed solely by a single locus.
All traits are governed solely by a single locus.
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What phenomenon can produce missing gamete types during meiosis?
What phenomenon can produce missing gamete types during meiosis?
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The human genome consists of approximately ___ genes.
The human genome consists of approximately ___ genes.
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Match the terms with their definitions:
Match the terms with their definitions:
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What is the relationship between the probability of recombination events and the distance between loci on a chromosome?
What is the relationship between the probability of recombination events and the distance between loci on a chromosome?
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Phenotypic expression can be simply determined by counting allele frequencies.
Phenotypic expression can be simply determined by counting allele frequencies.
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What type of disorders are often influenced by recessive alleles and require two copies for expression?
What type of disorders are often influenced by recessive alleles and require two copies for expression?
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Which of the following processes contributes to microevolution?
Which of the following processes contributes to microevolution?
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Microevolution requires the presence of more than one allele at a locus within a population.
Microevolution requires the presence of more than one allele at a locus within a population.
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Name one of the four processes that can cause microevolution.
Name one of the four processes that can cause microevolution.
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Microevolution is the result of __________ occurring within populations.
Microevolution is the result of __________ occurring within populations.
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Match the following terms with their descriptions:
Match the following terms with their descriptions:
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What is the primary focus of microevolution?
What is the primary focus of microevolution?
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Gene flow and mutation are identical in their roles in altering allele frequencies.
Gene flow and mutation are identical in their roles in altering allele frequencies.
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What term describes the decline in fitness of a population due to inbreeding?
What term describes the decline in fitness of a population due to inbreeding?
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Mutation can be classified as beneficial, neutral, or ________ in terms of its effects on fitness.
Mutation can be classified as beneficial, neutral, or ________ in terms of its effects on fitness.
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Match the terms with their definitions regarding genetic concepts:
Match the terms with their definitions regarding genetic concepts:
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Which of the following is a potential effect of genetic drift?
Which of the following is a potential effect of genetic drift?
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Fitness only refers to an organism's ability to survive.
Fitness only refers to an organism's ability to survive.
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What is the role of spatially varying selection in local adaptation?
What is the role of spatially varying selection in local adaptation?
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What primarily causes changes in allele frequencies in finite populations?
What primarily causes changes in allele frequencies in finite populations?
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Larger populations experience stronger genetic drift than smaller populations.
Larger populations experience stronger genetic drift than smaller populations.
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What is the effect of genetic drift on genetic variation?
What is the effect of genetic drift on genetic variation?
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In genetics, the sampling variation inherent in a finite sample leads to differences in allele frequencies across __________.
In genetics, the sampling variation inherent in a finite sample leads to differences in allele frequencies across __________.
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Match the following scenarios with their effects on allele frequency:
Match the following scenarios with their effects on allele frequency:
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Which of the following directly influences the magnitude of change due to genetic drift?
Which of the following directly influences the magnitude of change due to genetic drift?
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What is genetic drift?
What is genetic drift?
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Genetic drift can overwhelm natural selection in small populations.
Genetic drift can overwhelm natural selection in small populations.
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What is the effect of inbreeding on genotype frequencies?
What is the effect of inbreeding on genotype frequencies?
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Inbreeding depression refers to an increase in fitness due to inbreeding.
Inbreeding depression refers to an increase in fitness due to inbreeding.
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What is the common consequence of inbreeding in small populations?
What is the common consequence of inbreeding in small populations?
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Inbreeding causes an increase in _____, which can decrease overall fitness.
Inbreeding causes an increase in _____, which can decrease overall fitness.
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Match the following terms related to inbreeding with their descriptions:
Match the following terms related to inbreeding with their descriptions:
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Which of the following effects can inbreeding have on broader biological fields?
Which of the following effects can inbreeding have on broader biological fields?
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Inbreeding effects on genotype frequencies are permanent and cannot revert back.
Inbreeding effects on genotype frequencies are permanent and cannot revert back.
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Name a historical figure often associated with the negative effects of inbreeding.
Name a historical figure often associated with the negative effects of inbreeding.
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What is necessary for natural selection to occur?
What is necessary for natural selection to occur?
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Natural selection is the only mechanism of evolution.
Natural selection is the only mechanism of evolution.
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What is meant by 'Darwinian fitness'?
What is meant by 'Darwinian fitness'?
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Natural selection acts on __________, which are influenced by genetic variation.
Natural selection acts on __________, which are influenced by genetic variation.
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Match the evolutionary mechanism with its description:
Match the evolutionary mechanism with its description:
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What are the three conditions necessary for natural selection to produce evolutionary change?
What are the three conditions necessary for natural selection to produce evolutionary change?
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Only advantageous phenotypes can be passed on through natural selection.
Only advantageous phenotypes can be passed on through natural selection.
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How does genetic drift affect allele frequencies in a population?
How does genetic drift affect allele frequencies in a population?
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The trait's contribution to the next generation is referred to as its __________.
The trait's contribution to the next generation is referred to as its __________.
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Which of the following statements best represents the outcome of natural selection?
Which of the following statements best represents the outcome of natural selection?
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What does setting migration to 'island' imply in a population study?
What does setting migration to 'island' imply in a population study?
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A severe decrease in population size can enhance genetic drift.
A severe decrease in population size can enhance genetic drift.
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What is a population bottleneck?
What is a population bottleneck?
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The probability of an allele eventually getting fixed by drift is equal to its current ________ frequency.
The probability of an allele eventually getting fixed by drift is equal to its current ________ frequency.
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Match the following health conditions with their associated populations:
Match the following health conditions with their associated populations:
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Which of the following factors can lead to a population bottleneck?
Which of the following factors can lead to a population bottleneck?
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Founder events can have negative consequences for population persistence.
Founder events can have negative consequences for population persistence.
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What is the effect of increased gene flow on allele frequencies among populations?
What is the effect of increased gene flow on allele frequencies among populations?
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What term is used to describe random mating in a population?
What term is used to describe random mating in a population?
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Non-random mating affects allele frequencies in a population.
Non-random mating affects allele frequencies in a population.
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Which of the following best defines microevolution?
Which of the following best defines microevolution?
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Gene flow and mutation serve identical roles in altering allele frequencies.
Gene flow and mutation serve identical roles in altering allele frequencies.
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What are two forms of non-random mating?
What are two forms of non-random mating?
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Mating that occurs between individuals of different phenotypes is called ________ mating.
Mating that occurs between individuals of different phenotypes is called ________ mating.
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Match the types of mating with their definitions:
Match the types of mating with their definitions:
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What is the primary impact of population bottlenecks?
What is the primary impact of population bottlenecks?
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Natural selection only affects phenotypic variations that are genetically inherited.
Natural selection only affects phenotypic variations that are genetically inherited.
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Identify a mechanism that has evolved to reduce the likelihood of inbreeding.
Identify a mechanism that has evolved to reduce the likelihood of inbreeding.
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Which of the following processes is NOT one of the four causes of microevolution?
Which of the following processes is NOT one of the four causes of microevolution?
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Microevolution leads directly to macroevolution.
Microevolution leads directly to macroevolution.
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Microevolution requires genetic variation, meaning there must be more than one ______ at a locus in a population.
Microevolution requires genetic variation, meaning there must be more than one ______ at a locus in a population.
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Match the following microevolutionary processes with their definitions:
Match the following microevolutionary processes with their definitions:
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What is the term used to describe the decrease in fitness due to an increase in homozygosity resulting from inbreeding?
What is the term used to describe the decrease in fitness due to an increase in homozygosity resulting from inbreeding?
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Inbreeding can lead to an increase in heterozygotes within a population.
Inbreeding can lead to an increase in heterozygotes within a population.
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What genetic consequence does inbreeding primarily cause in a population?
What genetic consequence does inbreeding primarily cause in a population?
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The phenomenon where a loss of genetic variation in small populations can be worsened by inbreeding is known as __________.
The phenomenon where a loss of genetic variation in small populations can be worsened by inbreeding is known as __________.
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Match the following outcomes of inbreeding with their effects:
Match the following outcomes of inbreeding with their effects:
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Which scenario can result from inbreeding depression?
Which scenario can result from inbreeding depression?
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One or a few generations of random mating can restore the Hardy-Weinberg expected genotype frequencies after inbreeding.
One or a few generations of random mating can restore the Hardy-Weinberg expected genotype frequencies after inbreeding.
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What does an increase in homozygosity due to inbreeding typically lead to in terms of population fitness?
What does an increase in homozygosity due to inbreeding typically lead to in terms of population fitness?
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What is primarily responsible for random changes in allele frequencies in finite populations?
What is primarily responsible for random changes in allele frequencies in finite populations?
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Smaller populations experience weaker genetic drift than larger populations.
Smaller populations experience weaker genetic drift than larger populations.
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Explain how genetic drift can lead to the loss of genetic variation in a population.
Explain how genetic drift can lead to the loss of genetic variation in a population.
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The decline in fitness of a population due to inbreeding is known as __________.
The decline in fitness of a population due to inbreeding is known as __________.
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Match the following concepts with their effects:
Match the following concepts with their effects:
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Which of the following is a consequence of genetic drift in small populations?
Which of the following is a consequence of genetic drift in small populations?
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The process of genetic drift can cause populations to diverge from each other.
The process of genetic drift can cause populations to diverge from each other.
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What is the effect of setting the migration rate to 0 in a population with drift?
What is the effect of setting the migration rate to 0 in a population with drift?
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As population size (N) increases, the magnitude of change in allele frequency due to drift becomes __________.
As population size (N) increases, the magnitude of change in allele frequency due to drift becomes __________.
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A population bottleneck increases genetic variation within a population.
A population bottleneck increases genetic variation within a population.
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What is one example of a disorder that can have increased frequency due to a bottleneck?
What is one example of a disorder that can have increased frequency due to a bottleneck?
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The probability of an allele eventually fixing due to drift is equal to its current ________.
The probability of an allele eventually fixing due to drift is equal to its current ________.
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Match the following effects with their causes in population genetics:
Match the following effects with their causes in population genetics:
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Which migration rate would likely lead to the most allele frequency divergence among populations?
Which migration rate would likely lead to the most allele frequency divergence among populations?
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Increased gene flow can enhance local adaptation.
Increased gene flow can enhance local adaptation.
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What can cause genetic drift to have a more pronounced effect in a population?
What can cause genetic drift to have a more pronounced effect in a population?
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Which of the following processes does NOT contribute to microevolution?
Which of the following processes does NOT contribute to microevolution?
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Microevolution can occur without genetic variation.
Microevolution can occur without genetic variation.
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Name one of the four processes that can lead to microevolution.
Name one of the four processes that can lead to microevolution.
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The long-term and higher taxonomic consequences of microevolution are referred to as __________.
The long-term and higher taxonomic consequences of microevolution are referred to as __________.
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Match the following processes with their effects on allele frequencies:
Match the following processes with their effects on allele frequencies:
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What is the term used to describe the decrease in fitness as a consequence of inbreeding?
What is the term used to describe the decrease in fitness as a consequence of inbreeding?
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Inbreeding increases the frequency of heterozygotes in a population.
Inbreeding increases the frequency of heterozygotes in a population.
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What effect does inbreeding have on genetic variation in small populations?
What effect does inbreeding have on genetic variation in small populations?
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Inbreeding leads to an increase in _______ across the genome.
Inbreeding leads to an increase in _______ across the genome.
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Which of the following statements is true regarding the effects of inbreeding?
Which of the following statements is true regarding the effects of inbreeding?
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One or a few generations of random mating can restore Hardy-Weinberg expected genotype frequencies.
One or a few generations of random mating can restore Hardy-Weinberg expected genotype frequencies.
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Name one consequence of inbreeding depression.
Name one consequence of inbreeding depression.
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What is the primary mechanism by which gene flow can impede local adaptation?
What is the primary mechanism by which gene flow can impede local adaptation?
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The dominance hypothesis suggests that deleterious alleles are typically dominant within a population.
The dominance hypothesis suggests that deleterious alleles are typically dominant within a population.
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What term describes the negative impact on fitness from mating between populations with different adaptations?
What term describes the negative impact on fitness from mating between populations with different adaptations?
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When gene flow is __________, populations can diverge due to differing local selection pressures.
When gene flow is __________, populations can diverge due to differing local selection pressures.
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Match the types of gene flow with their effects:
Match the types of gene flow with their effects:
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Which of the following statements about gene flow is true?
Which of the following statements about gene flow is true?
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Gene flow can lead to the establishment of a single panmictic population if it is high enough.
Gene flow can lead to the establishment of a single panmictic population if it is high enough.
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Explain a way in which gene flow can promote adaptation of a population to its environment.
Explain a way in which gene flow can promote adaptation of a population to its environment.
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What happens to genetic divergence among populations when the migration rate is set to 0?
What happens to genetic divergence among populations when the migration rate is set to 0?
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Population bottlenecks enhance genetic variation.
Population bottlenecks enhance genetic variation.
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What is the primary consequence of a founder event?
What is the primary consequence of a founder event?
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An increase in the frequency of a deleterious mutation in an isolated population can have human health implications, such as ________ in the Amish community.
An increase in the frequency of a deleterious mutation in an isolated population can have human health implications, such as ________ in the Amish community.
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Match the following terms related to genetic drift with their definitions:
Match the following terms related to genetic drift with their definitions:
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Which migration rate is expected to produce the least divergence among populations?
Which migration rate is expected to produce the least divergence among populations?
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Increased genetic drift has no effect on allele frequencies in large populations.
Increased genetic drift has no effect on allele frequencies in large populations.
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Give an example of a condition that has become more prevalent due to a bottleneck effect.
Give an example of a condition that has become more prevalent due to a bottleneck effect.
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What is the primary consequence of genetic drift in small populations?
What is the primary consequence of genetic drift in small populations?
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What term describes the randomness of allele frequency changes across generations?
What term describes the randomness of allele frequency changes across generations?
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The magnitude of genetic drift is __________ related to population size.
The magnitude of genetic drift is __________ related to population size.
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Which factor primarily causes changes in allele frequencies in finite populations?
Which factor primarily causes changes in allele frequencies in finite populations?
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Match the terms with their respective effects:
Match the terms with their respective effects:
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If random mating occurs, drift-induced deviations from Hardy-Weinberg expected genotype frequencies are usually __________.
If random mating occurs, drift-induced deviations from Hardy-Weinberg expected genotype frequencies are usually __________.
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Name one scenario that can be simulated to observe the effects of genetic drift.
Name one scenario that can be simulated to observe the effects of genetic drift.
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Which of the following conditions is NOT necessary for natural selection to occur?
Which of the following conditions is NOT necessary for natural selection to occur?
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Natural selection can cause allele frequencies to change across generations.
Natural selection can cause allele frequencies to change across generations.
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Name one mechanism of microevolution.
Name one mechanism of microevolution.
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The term 'Darwinian fitness' refers to an individual's contribution to the ________ generation.
The term 'Darwinian fitness' refers to an individual's contribution to the ________ generation.
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Which of the following best describes genetic drift?
Which of the following best describes genetic drift?
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Fitness is solely determined by an organism's ability to survive.
Fitness is solely determined by an organism's ability to survive.
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What is the primary effect of inbreeding on a population?
What is the primary effect of inbreeding on a population?
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Natural selection leads to the evolution of traits that increase an organism's ________ in a given environment.
Natural selection leads to the evolution of traits that increase an organism's ________ in a given environment.
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Which of the following is a potential effect of gene flow?
Which of the following is a potential effect of gene flow?
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Study Notes
Genetics and the Modern Evolutionary Synthesis
- This topic covers the relationship between genetics and the evolution theory.
- It assumes a basic understanding of meiosis.
- Chapter 13 of Campbell and one or more videos on 'Additional Resources' can be reviewed for further details on meiosis
Learning Objectives
- Contrast blending and particulate inheritance.
- Outline Weismann's germ plasm theory.
- Explain Mendel's three laws using modern terminology.
- Understand the concept of a Punnett square for determining offspring genotypes.
- Utilize probability rules and Punnett squares to calculate the likelihood of specific genotypes given parental genotypes.
- Define and differentiate genetic terms such as locus, gene, allele, heterozygote, and homozygote.
- Describe the two main causes of continuous variation in traits.
- Estimate allele and genotype frequencies, including the calculation of p², 2pq, and q².
- Understand assumptions for the Hardy-Weinberg Equilibrium.
- Conduct Hardy-Weinberg equilibrium tests for a certain locus, using genotype frequencies and allele frequencies.
Early Theories of Inheritance
- Blending inheritance theory proposes that offspring traits are a mix of parent traits.
- Darwin's pangenesis theory suggests that hereditary information from all body parts accumulates in reproductive organs and passes to offspring.
- Fleeming Jenkin argued that blending inheritance causes a loss of variation over time, making natural selection ineffective.
- Francis Galton's experiments on rabbits did not support pangenesis.
- Weismann's germ plasm theory proposes that hereditary information is only carried by germ cells, and that somatic cells do not transmit hereditary information.
August Weismann
- Weismann (1834-1914) was a notable evolutionary theorist after Darwin.
- He was convinced that Lamarckian inheritance of acquired characteristics was incorrect through experiments.
- He developed the germ plasm theory in 1892.
Mendel's Success
- Mendel successfully used pea plants in his experiments.
- He deliberately chose easily observable traits to analyze across generations.
- He deliberately chose true-breeding plants.
- Mendel carefully followed multiple generations of plants.
Typical Breeding Experiment
- Mendel crossed true-breeding plants (P generation) and analyzed their offspring (F1, F2 generations).
- The F1 generation showed a single trait/phenotype.
- The F2 generation showed a ratio of traits that was 3:1 .
Mendelian Inheritance
- Mendel's observations indicated that traits were not blended.
- The traits were not lost or diluted, but were carried and reappeared in future generations.
Mendel's Model of Particulate Inheritance
- Mendel proposed a model where inheritance was controlled by distinct "factors" (today's genes).
- Different forms of these factors (today's alleles) lead to variations in phenotypes.
- Every individual carries two factors, one inherited from each parent.
Modern Terminology
- Genes are specific sequences of DNA or RNA.
- Locus is a location on a chromosome, which may or may not contain a gene.
- Alleles are different sequence versions for genes at a given locus
Mendel's Laws
- Law of dominance states that one allele in a gene pair can mask the effect of the other.
- Law of segregation states that alleles segregate during gamete formation.
- Two alleles at a locus sort into separate gametes regardless of the alleles at other loci (law of independent assortment).
Meiosis in a Double Heterozygote (Dihybrid)
- Independent assortment happens when non-homologous chromosomes align and separate at metaphase 1 in a way that produces a mixture of parental allele combinations in gametes.
Probability Governs Mendelian Inheritance
- Probability rules guide Mendelian inheritance.
- Independent events have no relationship to their outcome, like tossing a coin repeatedly
Mendel's Law of Independent Assortment
- Mendel, by observing different traits, recognized independent assortment of traits for different genes.
- Offspring can inherit different allele combinations from parents in gametes.
Meiosis
- This process produces sperm and egg cells, each with half the number of chromosomes.
- Each gamete has a single allele for each gene.
Phenotype Versus Genotype
- Phenotype: Observable traits or characteristics of an organism.
- Genotype: Genetic makeup of an organism, determined by specific alleles.
Inheritance Patterns are More Complex
- Pleiotropy means that a single gene can influence multiple traits.
- Multiple alleles (more than two) may exist for a single gene locus.
- Genes can be linked; alleles are inherited together when close on a chromosome.
Polygenic Traits
- Polygenic: Traits influenced by more than one gene, producing a continuous range of phenotypes, such as height, skin color,
- Environment also affects the traits.
- The trait's phenotype can vary depending on the environment.
Hardy-Weinberg Principle
- This offers a mathematical tool to depict the equilibrium of genotype and allele frequencies under certain conditions.
- The law states p2 + 2pq + q2 = 1, where p and q determine the allele frequencies.
Hardy-Weinberg Assumptions
- Random mating (no choice of mate based on genes)
- No natural selection favoring certain alleles
- No mutation at the locus
- No population migration (no individuals entering/leaving the population)
- Infinitely large population (lack of genetic drift)
Hardy-Weinberg in Reverse
- Estimate allele frequencies from known genotype frequencies, assuming equilibrium conditions.
- Phenylketonuria (PKU) can be used as an example to illustrate this method.
What is a Population?
- A group of interbreeding individuals of the same species within the same geographical location form a population.
Gene Pools
- Allele frequencies
- Genotype frequencies
Additional Topics
- Rediscovery of Mendel's work 1908
- Biometricians vs. Mendelians
- Reconciliation
Studying That Suits You
Use AI to generate personalized quizzes and flashcards to suit your learning preferences.
Description
Dive into the intricate relationship between genetics and the theory of evolution in this quiz based on Chapter 13 of Campbell. You will explore topics such as Mendel's laws, Punnett squares, and the Hardy-Weinberg Equilibrium, enhancing your understanding of genetic concepts and their applications in evolutionary biology.