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Questions and Answers
What is the composition of adult haemoglobin tetramer?
What is the composition of adult haemoglobin tetramer?
- Two α and two γ-globins
- Two β and two δ-globins
- Two α and two β-globins (correct)
- Two β and two γ-globins
During which stage of gestation is fetal hemoglobin prevalent?
During which stage of gestation is fetal hemoglobin prevalent?
- Third trimester
- Second trimester (correct)
- None of the trimesters
- First trimester
What is the major cause of sickle cell disease complications in newborns?
What is the major cause of sickle cell disease complications in newborns?
- Low concentration of fetal hemoglobin (correct)
- Presence of adult hemoglobin
- Co-inheritance of Hereditary Persistence of Fetal Hemoglobin (HPFH)
- Genetic mutations in α-globin genes
What is characteristic of patients with sickle-cell disease who co-inherited Hereditary Persistence of Fetal Hemoglobin?
What is characteristic of patients with sickle-cell disease who co-inherited Hereditary Persistence of Fetal Hemoglobin?
Which region is responsible for the regulation of globin gene clusters?
Which region is responsible for the regulation of globin gene clusters?
How is Hereditary Persistence of Fetal Hemoglobin typically caused?
How is Hereditary Persistence of Fetal Hemoglobin typically caused?
What happens to fetal hemoglobin after birth?
What happens to fetal hemoglobin after birth?
Why do newborn babies not manifest sickle-cell disease complications until they are around 6 months old?
Why do newborn babies not manifest sickle-cell disease complications until they are around 6 months old?
Which type of hemoglobin protects against sickle-cell disease?
Which type of hemoglobin protects against sickle-cell disease?
What is the impact of Hereditary Persistence of Fetal Hemoglobin (HPFH) on individuals with sickle-cell disease?
What is the impact of Hereditary Persistence of Fetal Hemoglobin (HPFH) on individuals with sickle-cell disease?
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