Genetic Material Detection and Bacteriophage Life Cycle

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18 Questions

In the Hershey-Chase Waring blender experiment, what was the purpose of using the blender?

To determine whether DNA or protein was the genetic material.

What can bacteriophages be used to test?

Which substance contained information to produce new phage.

How do bacteriophages replicate themselves inside a bacterial host?

By injecting their genetic material into the bacterial cell.

What is the key feature of the Watson-Crick model for DNA structure?

It has a helical structure.

What did Wilkins and Franklin use X-rays for in determining DNA patterns?

To show the helical structure of DNA.

What did the transformation principle seek to explain?

Whether DNA or protein was the genetic material.

What was the major component of 'nuclein' extracted by Meischer in 1869 from human white blood cells?

Deoxyribonucleic acid (DNA)

What did the Feulgen reaction in 1923 reveal about DNA?

DNA is located almost exclusively within chromosomes

Which scientists demonstrated bacterial transformation, implicating DNA as the substance of genes?

Avery, MacLeod, and McCarty

What did Hershey and Chase use in their blender experiments to study DNA’s function?

Viruses (bacteriophages)

In Hershey-Chase's Waring blender experiment, which component of the bacteriophage T2 was labeled with radioactive sulfur?

Protein coat (capsid)

What did the blender experiments of Hershey and Chase reveal about DNA?

DNA is the genetic material that infects bacteria

What was the main finding of Griffith's experiment with two strains of Streptococcus pneumoniae?

Heat-killed S cells transformed R cells into S cells

What substance did Avery, MacLeod, and McCarty identify as the 'transforming principle' in their experiment?

DNA

What did Avery, MacLeod, and McCarty confirm about DNA in their experiments?

It is the 'transforming principle' substance

In the context of genetic transformation, what is the significance of R and S strains of Streptococcus pneumoniae?

S strain can transform R strain

What did Griffith's experiments and Avery, MacLeod, and McCarty's work collectively establish about genetic material?

Genetic material can be transferred and alter characteristics

'Transforming principle' mentioned in the context of Avery, MacLeod, and McCarty's work refers to:

'Transforming substance' for genetic alteration

Learn about a simple system to test whether protein or DNA is the genetic material using bacteriophages. Explore the life cycle of bacteriophage T2 and how they replicate inside bacterial hosts.

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