Genetic Components of Variance and Genotypic Correlation Quiz

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20 Questions

What are the genetic components of variability that contribute to the total amount of genetic variation responsible for a phenotypic trait?

VA, VD, VI

What is the genotypic intra-class correlation originally recognized by statistical geneticists?

Ratio of VG to VP

What does the correlation among repeated measures represent?

Covariance between Yij and Yij’

How is the correlation among repeated measures represented?

(Equation 5)

What is the formula for the correlation among repeated measures in terms of covariance and variance?

ρ (Yij, Yij′) = Cov (Yij, Yij′) / Var (Yij) * Var (Yij′)

What is the formula for estimating broad sense heritability?

V(G)/V(P)

What does the genotypic variance consist of in the composition of total genotypic variance (V_G = V_A + V_D + V_I)?

The variance of breeding values due to inheritance of a particular allele

What is the purpose of distinguishing heritability in the broad sense from the concept of repeatability?

To apply intra-class correlation to animals

What is the formula for heritability in the narrow sense, as defined by JL Lush?

h^2 = VA/VP

What does broad sense heritability estimate?

The extent to which phenotypes are determined by genes transmitted from parents

The genetic components of variability responsible for a phenotypic trait include additive variance, VA, dominance variance, VD, and epistatic variance, VI.

True

The total amount of genetic variation responsible for a phenotypic trait can be represented as VP = VG + VE.

True

The genotypic intra-class correlation is originally recognized by statistical geneticists such as RA Fisher.

True

The correlation among repeated measures is represented by the equation: $\rho(Y_{ij}, Y_{ij'}) = \frac{Cov(Y_{ij}, Y_{ij'})}{\sqrt{Var(Y_{ij})Var(Y_{ij'})}}$.

False

The correlation among repeated measures is represented by the equation: $\rho(Y_{ij}, Y_{ij'}) = Cov(Y_{ij}, Y_{ij'}) \times Var(Y_{ij}) \times Var(Y_{ij'})$.

False

Broad sense heritability is estimated using Equation 6, where V_G represents the total genetic variance and V_P represents the phenotypic variance.

True

The narrow sense heritability, denoted as h^2, is defined by the equation h^2 = V_A / V_P, where V_A represents the additive genetic variance and V_P represents the phenotypic variance.

True

Repeatability, as referred to by JL Lush, is a concept related to broad sense heritability.

False

The genotypic variance consists of additive genetic variance, dominance variance, and epistatic variance, as represented by V_G = V_A + V_D + V_I.

True

The intra-class correlation coefficient was originally recognized as heritability in the broad sense by JL Lush in 1937.

True

Test your understanding of genetic components of variance, including additive variance, dominance variance, and epistatic variance. Explore the concept of genotypic intra-class correlation and its significance in statistical genetics.

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