Genetic Basis of Leukemia Susceptibility
12 Questions
0 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What distinguishes the 'acute' form of leukemia from the 'chronic' form?

  • Ratio of white blood cells to red blood cells
  • Type of white blood cells
  • Site of origin in the body
  • Duration and severity (correct)
  • Where is the granulocytic type of leukemia presumed to arise?

  • Red bone marrow (correct)
  • Lymph glands
  • Thymus
  • Spleen
  • What did Sacks and Seeman report about the death rate from leukemia from 1900 to 1944?

  • It fluctuated randomly
  • It decreased steadily
  • It remained constant
  • It increased steadily (correct)
  • Which of the following is NOT considered a possible source for the lymphocytic type of leukemia?

    <p>Bone marrow</p> Signup and view all the answers

    What is indicated by a linear relationship between dose of radiation and incidence of leukemia?

    <p>Some individuals only require one radiation-induced event to develop leukemia.</p> Signup and view all the answers

    What complicates the analysis of the hereditary component in leukemia?

    <p>Cases of leukemia which arise somatically.</p> Signup and view all the answers

    In relation to radiation-induced leukemia, why might some individuals require more than one event to develop leukemia?

    <p>They may need multiple gene mutations to develop leukemia.</p> Signup and view all the answers

    What is suggested by the work of MacDowell and associates regarding certain strains of mice and susceptibility to leukemia?

    <p>Differences in susceptibility to leukemia have a genetic basis.</p> Signup and view all the answers

    Which type of leukemia is assumed to have a probability of 1 x 10^-6 per individual per rad to the red marrow per year?

    <p>Both granulocytic and lymphocytic leukemias</p> Signup and view all the answers

    What is the 'best' estimate of the probability of leukemia of lymphatic origin per individual per rad to the lymphatic system per year?

    <p>1 x 10^-6</p> Signup and view all the answers

    What is uncertain about the predominance of lymphocytic leukemia in the thymic enlargement series?

    <p>Differentiating granulocytic and lymphocytic types in infants and children</p> Signup and view all the answers

    What type of leukemia is primarily observed following irradiation of the spinal marrow according to the evidence mentioned?

    <p>Granulocytic leukemia</p> Signup and view all the answers

    More Like This

    Ch 6 (pp 119-124)
    30 questions

    Ch 6 (pp 119-124)

    SublimeSardonyx avatar
    SublimeSardonyx
    Acute Myeloid Leukemia Overview
    8 questions
    Use Quizgecko on...
    Browser
    Browser