Podcast
Questions and Answers
Which of the following best describes the difference between oncogenes and tumor suppressor genes?
Which of the following best describes the difference between oncogenes and tumor suppressor genes?
- Oncogenes inhibit tumorigenesis, while tumor suppressor genes promote it.
- Oncogenes and tumor suppressor genes have the same function in tumorigenesis.
- Oncogenes have no role in tumorigenesis, while tumor suppressor genes are essential.
- Oncogenes act as accelerators, while tumor suppressor genes act as brakes in tumorigenesis. (correct)
How do mutations in oncogenes typically occur?
How do mutations in oncogenes typically occur?
- They are always frameshift mutations leading to truncated proteins.
- They are usually nonsense mutations affecting both alleles.
- They are often missense mutations affecting specific hotspots or neighboring codons. (correct)
- They occur randomly throughout the gene.
What is a characteristic of mutations in tumor suppressor genes?
What is a characteristic of mutations in tumor suppressor genes?
- They are always missense mutations affecting one allele.
- They are clustered at specific hotspots in the gene.
- They are typically nonsense mutations affecting only one allele.
- They often lead to truncated proteins and affect both alleles, causing loss of heterozygosity. (correct)
Which of the following is NOT mentioned as a major type of somatic mutation present in malignant tumors?
Which of the following is NOT mentioned as a major type of somatic mutation present in malignant tumors?
Which statement is correct regarding the mutations in oncogenes?
Which statement is correct regarding the mutations in oncogenes?
Which of the following types of mutations is NOT mentioned in the text?
Which of the following types of mutations is NOT mentioned in the text?
What was the significance of the completion of the Human Genome Project?
What was the significance of the completion of the Human Genome Project?
What was the significance of the construction of the HapMap?
What was the significance of the construction of the HapMap?
Which of the following cancer genes were successfully discovered before the elucidation of the human genome?
Which of the following cancer genes were successfully discovered before the elucidation of the human genome?
What was the first curated version of the Human Genome Project?
What was the first curated version of the Human Genome Project?
What did the information from the Human Genome Project and the HapMap allow?
What did the information from the Human Genome Project and the HapMap allow?
What was the ambitious goal that became within reach of the scientific community for the first time?
What was the ambitious goal that became within reach of the scientific community for the first time?
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