Questions and Answers
Which of the following best describes the difference between oncogenes and tumor suppressor genes?
Oncogenes act as accelerators, while tumor suppressor genes act as brakes in tumorigenesis.
How do mutations in oncogenes typically occur?
They are often missense mutations affecting specific hotspots or neighboring codons.
What is a characteristic of mutations in tumor suppressor genes?
They often lead to truncated proteins and affect both alleles, causing loss of heterozygosity.
Which of the following is NOT mentioned as a major type of somatic mutation present in malignant tumors?
Signup and view all the answers
Which statement is correct regarding the mutations in oncogenes?
Signup and view all the answers
Which of the following types of mutations is NOT mentioned in the text?
Signup and view all the answers
What was the significance of the completion of the Human Genome Project?
Signup and view all the answers
What was the significance of the construction of the HapMap?
Signup and view all the answers
Which of the following cancer genes were successfully discovered before the elucidation of the human genome?
Signup and view all the answers
What was the first curated version of the Human Genome Project?
Signup and view all the answers
What did the information from the Human Genome Project and the HapMap allow?
Signup and view all the answers
What was the ambitious goal that became within reach of the scientific community for the first time?
Signup and view all the answers
