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Questions and Answers
The symptoms of generalized anxiety disorder (GAD) are confined to specific situations.
The symptoms of generalized anxiety disorder (GAD) are confined to specific situations.
False (B)
GAD can present all symptoms of anxiety as illustrated in the corresponding box.
GAD can present all symptoms of anxiety as illustrated in the corresponding box.
True (A)
The anxiety symptoms in GAD are usually more intense during certain situations compared to others.
The anxiety symptoms in GAD are usually more intense during certain situations compared to others.
False (B)
There is a characteristic pattern of features associated with GAD.
There is a characteristic pattern of features associated with GAD.
Phobic anxiety disorders share the same symptom pattern as generalized anxiety disorder.
Phobic anxiety disorders share the same symptom pattern as generalized anxiety disorder.
Worry and apprehension in patients with Generalized Anxiety Disorder are usually less chronic than in healthy individuals.
Worry and apprehension in patients with Generalized Anxiety Disorder are usually less chronic than in healthy individuals.
The DSM-5 and ICD-10 have identical requirements for the duration of symptoms in Generalized Anxiety Disorder.
The DSM-5 and ICD-10 have identical requirements for the duration of symptoms in Generalized Anxiety Disorder.
Muscle tension in Generalized Anxiety Disorder may manifest as restlessness, headache, and tremors.
Muscle tension in Generalized Anxiety Disorder may manifest as restlessness, headache, and tremors.
Autonomic overactivity is commonly associated with symptoms such as dizziness and dry mouth in Generalized Anxiety Disorder.
Autonomic overactivity is commonly associated with symptoms such as dizziness and dry mouth in Generalized Anxiety Disorder.
Depressive symptoms are never present in cases of Generalized Anxiety Disorder.
Depressive symptoms are never present in cases of Generalized Anxiety Disorder.
In the ICD-10, cases presenting significant symptoms of both anxiety and depressive disorders are categorized under mixed anxiety and depressive disorder.
In the ICD-10, cases presenting significant symptoms of both anxiety and depressive disorders are categorized under mixed anxiety and depressive disorder.
The criteria for anxiety symptoms in the DSM-5 includes a key emphasis on the presence of worry.
The criteria for anxiety symptoms in the DSM-5 includes a key emphasis on the presence of worry.
Sleep disturbances in Generalized Anxiety Disorder are typically associated with refreshing and uninterrupted sleep.
Sleep disturbances in Generalized Anxiety Disorder are typically associated with refreshing and uninterrupted sleep.
Generalized Anxiety Disorder is characterized by persistent and excessive fear that is easy to control.
Generalized Anxiety Disorder is characterized by persistent and excessive fear that is easy to control.
Cognitive-behavioral therapy is an effective treatment for Generalized Anxiety Disorder.
Cognitive-behavioral therapy is an effective treatment for Generalized Anxiety Disorder.
The prevalence of GAD is higher in men compared to women.
The prevalence of GAD is higher in men compared to women.
Early adverse experiences can increase the risk of developing Generalized Anxiety Disorder.
Early adverse experiences can increase the risk of developing Generalized Anxiety Disorder.
Benzodiazepines should be prescribed for longer than three weeks to manage GAD effectively.
Benzodiazepines should be prescribed for longer than three weeks to manage GAD effectively.
Self-treatment is strongly recommended for those experiencing symptoms of Generalized Anxiety Disorder.
Self-treatment is strongly recommended for those experiencing symptoms of Generalized Anxiety Disorder.
SSRIs are typically the first line of treatment for GAD.
SSRIs are typically the first line of treatment for GAD.
Benzodiazepines are commonly used for long-term treatment of Generalized Anxiety Disorder.
Benzodiazepines are commonly used for long-term treatment of Generalized Anxiety Disorder.
Social factors such as unemployment can increase the risk of Generalized Anxiety Disorder.
Social factors such as unemployment can increase the risk of Generalized Anxiety Disorder.
Cognitive behavioural therapy and applied relaxation are both considered structured psychological treatments for GAD.
Cognitive behavioural therapy and applied relaxation are both considered structured psychological treatments for GAD.
Physical symptoms of GAD can include headaches and abdominal discomfort.
Physical symptoms of GAD can include headaches and abdominal discomfort.
A stepped-care approach is recommended for the treatment of generalized anxiety disorder.
A stepped-care approach is recommended for the treatment of generalized anxiety disorder.
Recognizing that GAD is a long-term problem is irrelevant when discussing treatment plans.
Recognizing that GAD is a long-term problem is irrelevant when discussing treatment plans.
ICD-10 allows diagnosis of GAD if symptoms meet criteria for panic disorder.
ICD-10 allows diagnosis of GAD if symptoms meet criteria for panic disorder.
DSM-5 prioritizes worrying ideas in diagnosing GAD even if other anxiety symptoms are present.
DSM-5 prioritizes worrying ideas in diagnosing GAD even if other anxiety symptoms are present.
Comorbidity between GAD and other anxiety disorders is rare.
Comorbidity between GAD and other anxiety disorders is rare.
Severe depressive disorders are often misdiagnosed as GAD.
Severe depressive disorders are often misdiagnosed as GAD.
Anxiety in Parkinson's disease is often misdiagnosed as GAD.
Anxiety in Parkinson's disease is often misdiagnosed as GAD.
In thyrotoxicosis, anxiety symptoms can include irritability and tremor.
In thyrotoxicosis, anxiety symptoms can include irritability and tremor.
Patients with schizophrenia do not report anxiety symptoms.
Patients with schizophrenia do not report anxiety symptoms.
Morning anxiety symptoms suggest a depressive disorder.
Morning anxiety symptoms suggest a depressive disorder.
Substance misuse can lead to a false perception of anxiety symptoms during withdrawal.
Substance misuse can lead to a false perception of anxiety symptoms during withdrawal.
Phaeochromocytoma is likely to mimic symptoms of a generalized anxiety disorder.
Phaeochromocytoma is likely to mimic symptoms of a generalized anxiety disorder.
Conditioning theories propose that GAD is solely a result of environmental factors without any genetic predisposition.
Conditioning theories propose that GAD is solely a result of environmental factors without any genetic predisposition.
The amygdala plays a critical role in mediating anxiety by receiving sensory information.
The amygdala plays a critical role in mediating anxiety by receiving sensory information.
Cognitive biases associated with GAD include a decreased attention to potential threats.
Cognitive biases associated with GAD include a decreased attention to potential threats.
The hippocampus is irrelevant to the regulation of anxiety according to current cognitive theories.
The hippocampus is irrelevant to the regulation of anxiety according to current cognitive theories.
Meta-cognitive beliefs can lead to a recognition that worry is necessary but also harmful among GAD sufferers.
Meta-cognitive beliefs can lead to a recognition that worry is necessary but also harmful among GAD sufferers.
Animal studies have shown that noradrenergic neurons in the locus coeruleus are inhibitory and reduce anxiety.
Animal studies have shown that noradrenergic neurons in the locus coeruleus are inhibitory and reduce anxiety.
Twin studies have found no genetic overlap between neuroticism and GAD.
Twin studies have found no genetic overlap between neuroticism and GAD.
Functional imaging studies indicate consistent amygdala reactivity in GAD patients when exposed to aversive stimuli.
Functional imaging studies indicate consistent amygdala reactivity in GAD patients when exposed to aversive stimuli.
One of the DSM-5 criteria for GAD is the presence of symptoms for at least 3 months.
One of the DSM-5 criteria for GAD is the presence of symptoms for at least 3 months.
Corticotropin-releasing hormone is found in low concentration in the amygdala and reduces anxiety-related behaviors.
Corticotropin-releasing hormone is found in low concentration in the amygdala and reduces anxiety-related behaviors.
Generalized Anxiety Disorder (GAD) is typically a transient condition with high rates of remission.
Generalized Anxiety Disorder (GAD) is typically a transient condition with high rates of remission.
The average duration of illness for patients with GAD is approximately 10 years.
The average duration of illness for patients with GAD is approximately 10 years.
Self-help approaches for GAD generally involve significant therapist input.
Self-help approaches for GAD generally involve significant therapist input.
Cognitive behavior therapy has shown substantial benefits in the resolution of symptoms in patients with GAD.
Cognitive behavior therapy has shown substantial benefits in the resolution of symptoms in patients with GAD.
Medication for GAD can provide quick symptom control while waiting for psychological treatment to take effect.
Medication for GAD can provide quick symptom control while waiting for psychological treatment to take effect.
The use of relaxation training is equally effective regardless of whether it is practiced individually or in groups.
The use of relaxation training is equally effective regardless of whether it is practiced individually or in groups.
Research indicates that approximately 30% of patients achieved remission after taking escitalopram in a placebo-controlled trial.
Research indicates that approximately 30% of patients achieved remission after taking escitalopram in a placebo-controlled trial.
Relaxation training combined with yoga exercises can enhance engagement with treatment for GAD.
Relaxation training combined with yoga exercises can enhance engagement with treatment for GAD.
Applied relaxation therapy is effective in reducing anxiety over a span of 12 to 15 sessions.
Applied relaxation therapy is effective in reducing anxiety over a span of 12 to 15 sessions.
Patients with GAD who engage in self-help strategies demonstrate consistently high efficacy in symptom resolution.
Patients with GAD who engage in self-help strategies demonstrate consistently high efficacy in symptom resolution.
Benzodiazepines like Diazepam should be prescribed for more than 3 weeks due to their safety profile.
Benzodiazepines like Diazepam should be prescribed for more than 3 weeks due to their safety profile.
Buspirone has a faster onset of action compared to benzodiazepines.
Buspirone has a faster onset of action compared to benzodiazepines.
SSRIs are typically recommended as the first choice for long-term treatment of GAD.
SSRIs are typically recommended as the first choice for long-term treatment of GAD.
Pregabalin is effective for treating GAD and has the same side effect profile as SSRIs.
Pregabalin is effective for treating GAD and has the same side effect profile as SSRIs.
Beta-adrenergic antagonists are primarily utilized for the treatment of GAD rather than performance anxiety.
Beta-adrenergic antagonists are primarily utilized for the treatment of GAD rather than performance anxiety.
Patients with GAD should only seek psychological treatment without considering medication.
Patients with GAD should only seek psychological treatment without considering medication.
Maintaining treatment for at least 6 months reduces the risk of relapse in GAD patients.
Maintaining treatment for at least 6 months reduces the risk of relapse in GAD patients.
It is crucial to evaluate psychosocial maintaining factors in patients with GAD.
It is crucial to evaluate psychosocial maintaining factors in patients with GAD.
Selective serotonin reuptake inhibitors (SSRIs) are less well tolerated than serotonin and noradrenaline reuptake inhibitors (SNRIs).
Selective serotonin reuptake inhibitors (SSRIs) are less well tolerated than serotonin and noradrenaline reuptake inhibitors (SNRIs).
Education and self-help can be effective preliminary steps in managing anxiety before a GAD diagnosis is made.
Education and self-help can be effective preliminary steps in managing anxiety before a GAD diagnosis is made.
Flashcards
Generalized Anxiety Disorder (GAD)
Generalized Anxiety Disorder (GAD)
A chronic mental health condition characterized by persistent and excessive worry.
Key symptoms of GAD
Key symptoms of GAD
Include worry, muscle tension, autonomic overactivity, and sleep disturbances.
GAD diagnosis duration
GAD diagnosis duration
Symptoms must last at least 6 months for a diagnosis.
GAD comorbidity
GAD comorbidity
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Differential diagnosis for GAD
Differential diagnosis for GAD
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GAD causes (genetic)
GAD causes (genetic)
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GAD causes (early life)
GAD causes (early life)
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Prevalence of GAD
Prevalence of GAD
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GAD vs Gender
GAD vs Gender
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GAD treatments
GAD treatments
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CBT for GAD
CBT for GAD
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GAD treatment challenges
GAD treatment challenges
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Neurobiological mechanisms in GAD
Neurobiological mechanisms in GAD
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Cognitive mechanisms in GAD
Cognitive mechanisms in GAD
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GAD prognosis
GAD prognosis
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Primary care management of GAD
Primary care management of GAD
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Self-help methods for GAD
Self-help methods for GAD
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Applied Relaxation
Applied Relaxation
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Benzodiazepines in GAD
Benzodiazepines in GAD
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Psychoeducation for GAD
Psychoeducation for GAD
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Study Notes
Generalized Anxiety Disorder (GAD) Overview
- GAD is characterized by persistent, excessive worry that is difficult to control, impairing daily functioning.
- Symptoms include a mix of physical and mental manifestations such as muscle tension, sleep disturbances, and restlessness.
Clinical Symptoms
- Key symptoms in GAD include:
- Worry and apprehension
- Muscle tension
- Autonomic overactivity
- Psychological arousal
- Sleep disturbance
- Associated features may include depression, obsessions, and feelings of depersonalization.
Diagnostic Criteria
- GAD is diagnosed based on symptom frequency and duration, with symptoms lasting at least 6 months.
- The DSM-5 leverages key symptoms like worry to differentiate GAD while the ICD-10 has a broader list of physical symptoms.
- Clinically significant distress and impaired functioning are mandatory for DSM-5 diagnosis.
Comorbidity
- GAD frequently coexists with other disorders, including depression and various anxiety disorders, complicating diagnosis and treatment.
- Social phobia (23%), simple phobia (21%), and panic disorder (11%) are common comorbidities in GAD cases.
Differential Diagnosis
- Distinguishing GAD from other conditions is crucial, particularly from depressive disorders, schizophrenia, dementia, substance misuse, and physical illness.
- Important to inquire about the sequence and severity of symptoms to determine the primary diagnosis.
Causes of GAD
- Genetic predisposition, particularly a higher concordance in identical twins.
- Adverse early life experiences such as trauma or neglect can contribute to risk.
- Stressful life events like significant losses can be triggers.
Prevalence and Epidemiology
- Prevalence rates in the U.S. and England around 4.4%, lower in European countries at 2%.
- Women are notably affected more than men, with a prevalence rate about two times higher.
Treatment Approaches
- Treatment typically integrates therapy and medication, focusing on cognitive-behavioral therapy (CBT).
- CBT effectively addresses negative thought patterns; self-help and psychoeducation can supplement treatment.
- Anxiolytics (e.g., benzodiazepines) may be used for short-term relief; SSRIs often recommended for long-term management.
Treatment Challenges
- GAD is a chronic condition with low remission rates; long-term follow-up is often necessary due to comorbid disorders.
- Structured treatments like applied relaxation can be beneficial but require consistent practice from patients.
Neurobiological and Cognitive Mechanisms
- Neurobiological aspects include amygdala and hippocampal function; anxiety regulation involves neurotransmitters like serotonin and GABA.
- Cognitive theories propose that individuals with GAD may use worry as a coping strategy, potentially leading to a "worry about worry" cycle.
Prognosis
- Despite recurrent episodes and significant burdens, prognosis varies with treatment adherence.
- Continuation of effective treatment for at least six months markedly reduces relapse risk.
Management in Primary Care
- Initial steps may include self-help strategies; short-term benzodiazepine use may provide immediate relief.
- Psychoeducation is crucial for understanding GAD's impact and available treatment options.
Key Points on Self-help and Therapy
- Self-help methods can initiate treatment, often incorporating cognitive behavioral techniques.
- Group psychoeducation is available; limitations exist in terms of evidence for effectiveness but provide a sense of community.
Conclusion
- Comprehensive treatment of GAD includes a multidimensional approach tailored to individual needs, addressing both psychological and physiological symptoms efficiently.
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