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Questions and Answers

Which of the following best describes the primary function of astrocytes?

  • Acting as phagocytes to clear debris
  • Maintaining ionic balance and regulating neurotransmitter concentrations (correct)
  • Producing myelin to insulate axons
  • Transmitting electrical signals between neurons

Which glial cell type is responsible for the formation of myelin in the central nervous system?

  • Oligodendrocytes (correct)
  • Schwann cells
  • Astrocytes
  • Microglia

What is the primary function of myelin?

  • To create a physical barrier between neurons
  • To increase the speed of electrical signal transmission (correct)
  • To provide structural support for neurons
  • To regulate the release of neurotransmitters

How do microglia contribute to the health of the nervous system?

<p>They clear debris and modulate inflammatory responses (A)</p> Signup and view all the answers

Which statement accurately describes the difference between ionotropic and metabotropic receptors?

<p>Metabotropic receptors directly alter membrane permeability, while ionotropic receptors trigger intracellular changes. (A)</p> Signup and view all the answers

Which of the following is NOT a function of neuroglia?

<p>Transmitting electrical signals between neurons (B)</p> Signup and view all the answers

Which type of glial cell is implicated in the formation of tumors such as astrocytomas and glioblastomas?

<p>Astrocytes (C)</p> Signup and view all the answers

Which of the following is a characteristic of ionotropic receptors?

<p>They directly control the opening of ion channels. (B)</p> Signup and view all the answers

Which of the following cranial nerves are associated with the midbrain?

<p>Cranial nerves III and IV (B)</p> Signup and view all the answers

What structure in the midbrain is crucial for motor coordination and control, particularly during walking?

<p>Red nucleus (C)</p> Signup and view all the answers

The pons is located:

<p>Inferior to the midbrain and superior to the medulla (A)</p> Signup and view all the answers

Which region of the brainstem houses the nuclei for cranial nerves IX, X, XI, and XII?

<p>Medulla oblongata (B)</p> Signup and view all the answers

What is the primary function of the olivary nuclei, located in the medulla?

<p>Aiding cerebellar function and perception of sound (C)</p> Signup and view all the answers

Which of the following is NOT a function of the reticular activating system (RAS)?

<p>Controlling eye movement (B)</p> Signup and view all the answers

What neurotransmitters are produced by the raphe nuclei, locus coeruleus, and medial reticular area, which influence motor activity?

<p>Serotonin and norepinephrine (D)</p> Signup and view all the answers

Which of the following statements is TRUE about the reticular formation?

<p>It is a loose aggregation of cells spanning the brainstem and extending to the thalamus. (A)</p> Signup and view all the answers

What kind of signaling is referred to as essential throughout embryonic development?

<p>Inductive Signaling (A)</p> Signup and view all the answers

Which type of neuron is responsible for transmitting sensory information from the periphery to the central nervous system?

<p>Pseudounipolar Neuron (C)</p> Signup and view all the answers

Which of the following is NOT a characteristic of a multipolar neuron?

<p>Transmits sensory information from the periphery (B)</p> Signup and view all the answers

Which of the following statements is TRUE about inductive signaling?

<p>It involves the secretion of chemical signals that influence the fate of nearby cells. (C)</p> Signup and view all the answers

What is the primary function of bipolar neurons?

<p>Transmitting sensory information from the periphery. (A)</p> Signup and view all the answers

What is the outermost layer of the meninges called?

<p>Dura mater (B)</p> Signup and view all the answers

Which structure is formed from the inward folding of the dura mater that separates the left and right cerebral hemispheres?

<p>Falx cerebri (C)</p> Signup and view all the answers

Which layer of the meninges is highly vascularized and contributes to the blood-brain barrier?

<p>Pia mater (B)</p> Signup and view all the answers

The arachnoid mater plays a role in which of the following functions?

<p>Production and reabsorption of cerebrospinal fluid (A)</p> Signup and view all the answers

What are trabeculae in the context of the arachnoid mater?

<p>Connective tissue projections connecting to the pia mater (D)</p> Signup and view all the answers

Which meningeal layer is known for its spider web-like appearance?

<p>Arachnoid mater (A)</p> Signup and view all the answers

What function does the dura mater serve in relation to the brain and spinal cord?

<p>Providing structural support and protection (B)</p> Signup and view all the answers

The tentorium cerebelli separates which parts of the brain?

<p>Cerebrum and cerebellum (B)</p> Signup and view all the answers

What is a significant complication that can result from damage to the arteries specified?

<p>Serious complications, including death (B)</p> Signup and view all the answers

Which artery primarily supplies the medial portions of the frontal lobes and superior medial parietal lobes?

<p>Right and Left Anterior Cerebral Arteries (C)</p> Signup and view all the answers

What structure in the brain provides alternate routes for blood flow if larger arteries become blocked?

<p>Circle of Willis (D)</p> Signup and view all the answers

What do the anterior and posterior communicating arteries connect?

<p>The anterior and posterior circulations of the brain (D)</p> Signup and view all the answers

Which arteries primarily supply the occipital lobe and the inferior part of the temporal lobe?

<p>Right and Left Posterior Cerebral Arteries (B)</p> Signup and view all the answers

What role do the cerebral veins play in brain physiology?

<p>They drain oxygen-depleted blood from the brain (D)</p> Signup and view all the answers

What areas do the internal carotid arteries primarily supply?

<p>Anterior two-thirds of the cerebral hemispheres (B)</p> Signup and view all the answers

What is the primary function of the dural sinuses in the brain's venous system?

<p>Collect and drain oxygen-depleted blood (D)</p> Signup and view all the answers

What initiates the signal transmission in postsynaptic neurons?

<p>Neurotransmitter binding (D)</p> Signup and view all the answers

Which type of receptor opens ion channels directly upon neurotransmitter binding?

<p>Ionotropic receptors (B)</p> Signup and view all the answers

What characterizes metabotropic receptors compared to ionotropic receptors?

<p>Use of transduction mechanisms (B)</p> Signup and view all the answers

What type of communication do electrical synapses provide?

<p>Direct and rapid communication (A)</p> Signup and view all the answers

Which of the following is NOT a function of metabotropic receptors?

<p>Facilitating fast ion transport (A)</p> Signup and view all the answers

What primary signal type is involved in synaptic communication?

<p>Chemical signals primarily (B)</p> Signup and view all the answers

What distinguishes ionotropic receptors from metabotropic receptors in terms of action speed?

<p>Ionotropic receptors transmit signals instantaneously. (B)</p> Signup and view all the answers

Which of the following statements accurately describes the difference between the central nervous system (CNS) and the peripheral nervous system (PNS)?

<p>The CNS is protected by bone while the PNS is not. (B), The CNS is responsible for processing information while the PNS transmits information between the CNS and the rest of the body. (D)</p> Signup and view all the answers

Which of the following components are part of the peripheral nervous system?

<p>Cranial nerves (A)</p> Signup and view all the answers

Which of the following statements accurately describes the difference between tracts and nerves?

<p>Tracts are bundles of axons in the CNS, while nerves are bundles of axons in the PNS. (D)</p> Signup and view all the answers

Which of the following is NOT a characteristic of the autonomic nervous system?

<p>It is generally under conscious control. (D)</p> Signup and view all the answers

What is the primary function of the somatic nervous system?

<p>Control of skeletal muscles. (D)</p> Signup and view all the answers

What is the primary difference between oligodendrocytes and Schwann cells?

<p>Oligodendrocytes myelinate multiple axons, while Schwann cells myelinate only one axon. (A), Oligodendrocytes produce myelin in the CNS, while Schwann cells produce myelin in the PNS. (C)</p> Signup and view all the answers

How does the CNS differ from the PNS in terms of its resilience to injury?

<p>The CNS is less resilient to injury than the PNS. (D)</p> Signup and view all the answers

What is a key difference between gray matter and white matter in the CNS?

<p>Gray matter is composed of neuron cell bodies and unmyelinated axons, while white matter is composed primarily of myelinated axons. (C)</p> Signup and view all the answers

What is the primary function of the Olfactory nerve?

<p>Smell (D)</p> Signup and view all the answers

Which cranial nerve is primarily associated with vision?

<p>Optic nerve (D)</p> Signup and view all the answers

What would a lesion in the Olfactory nerve primarily affect?

<p>Sense of smell (C)</p> Signup and view all the answers

How can the function of the Optic nerve be clinically tested?

<p>Using an eye chart (C)</p> Signup and view all the answers

Which of the following is NOT a characteristic of the Olfactory nerve?

<p>It connects directly to the optic chiasm. (D)</p> Signup and view all the answers

What visual disturbance may result from damage to the PCA?

<p>Contralateral homonymous hemianopsia (A)</p> Signup and view all the answers

Which symptom is NOT commonly associated with occlusion of the vertebral and basilar arteries?

<p>Decreased appetite (C)</p> Signup and view all the answers

What is the most common location for a stroke in the posterior circulation?

<p>Posterior Inferior Cerebellar Artery (C)</p> Signup and view all the answers

Which clinical sign is a key indicator of a vascular problem during a stroke?

<p>Sudden weakness or numbness (B)</p> Signup and view all the answers

What common symptom is associated with damage to the Anterior Inferior Cerebellar Artery?

<p>Facial paralysis (B)</p> Signup and view all the answers

What is the primary goal of medical management following a hemorrhagic stroke?

<p>Repairing or removing the source of bleeding (D)</p> Signup and view all the answers

Which blood vessel's occlusion might lead to symptoms like slurred speech and sudden falls?

<p>Vertebral Artery (C)</p> Signup and view all the answers

What psychological symptom is often seen with posterior circulation strokes?

<p>Visual agnosia (B)</p> Signup and view all the answers

What is the primary function of the cortical homunculus in relation to the brain?

<p>It helps understand which parts of the brain control specific body parts. (A)</p> Signup and view all the answers

Which structure is located in the temporal lobe and is associated with memory and emotions?

<p>Uncus (C)</p> Signup and view all the answers

Where is the primary somatosensory cortex located?

<p>In the postcentral gyrus of the parietal lobe (B)</p> Signup and view all the answers

How are body parts represented in the motor homunculus?

<p>Larger areas for parts requiring fine motor control (B)</p> Signup and view all the answers

What role does the cuneus play in the occipital lobe?

<p>It plays a role in visual processing. (A)</p> Signup and view all the answers

Which of the following correctly describes the limbic lobe?

<p>A C-shaped compilation of structures involved in memory and emotion. (C)</p> Signup and view all the answers

What characterizes the representation of body parts in both the motor and sensory homunculi?

<p>They have exaggerated features relative to actual body proportions. (C)</p> Signup and view all the answers

What is the significance of locating the primary motor cortex in the precentral gyrus?

<p>It is crucial for voluntary motor control. (B)</p> Signup and view all the answers

What is the primary benefit of saltatory conduction in myelinated axons?

<p>It speeds up the transmission of action potentials. (C)</p> Signup and view all the answers

Which statement correctly describes the effect of demyelination on nerve signal transmission?

<p>It slows down or blocks nerve signal transmission. (D)</p> Signup and view all the answers

What is the role of ion channels in action potential generation?

<p>They allow the influx and efflux of specific ions to create a charge difference. (C)</p> Signup and view all the answers

How does myelin assist with nerve conduction?

<p>It insulates the axon and allows faster signal transmission. (C)</p> Signup and view all the answers

What happens during the depolarization phase of an action potential?

<p>Voltage-gated sodium channels open, allowing sodium to enter the cell. (C)</p> Signup and view all the answers

What consequence results from a lack of myelination in nerve fibers?

<p>Slowed or ineffective transmission of signals. (B)</p> Signup and view all the answers

During the general flow of information in a neuron, what pathway does the signal travel?

<p>From dendrites to axon to presynaptic terminal. (B)</p> Signup and view all the answers

Which type of ion movement is primarily responsible for creating the resting membrane potential?

<p>Potassium moving out of the neuron while sodium influx balances this. (B)</p> Signup and view all the answers

Which neurotransmitter is primarily responsible for muscle contraction?

<p>Acetylcholine (A)</p> Signup and view all the answers

What is the primary function of GABA in the central nervous system?

<p>To inhibit the transmission of signals (A)</p> Signup and view all the answers

What is the role of endocannabinoids in synaptic transmission?

<p>They provide an inhibitory effect by limiting the release of neurotransmitters. (C)</p> Signup and view all the answers

What is the primary effect of Botox on neurotransmission?

<p>Botox reduces the amount of calcium available in the presynaptic terminal, limiting acetylcholine release. (B)</p> Signup and view all the answers

What is the primary cause of weakness in Myasthenia Gravis?

<p>Destruction of postsynaptic receptors (A)</p> Signup and view all the answers

What is the difference between ionotropic and metabotropic receptors?

<p>Ionotropic receptors directly open ion channels, while metabotropic receptors use signaling cascades. (A)</p> Signup and view all the answers

Which of the following is NOT a characteristic of excitatory neurotransmitters?

<p>They can slow down nervous system transmission. (A)</p> Signup and view all the answers

What role do calcium ions play in neurotransmitter release?

<p>Calcium triggers the fusion of synaptic vesicles with the presynaptic membrane, releasing neurotransmitters. (D)</p> Signup and view all the answers

Flashcards

Inductive Signaling

Cells secrete signals that influence nearby cells' fate and development.

Multipolar Neuron

A neuron with many dendrites and one axon; common in the CNS.

Bipolar Neuron

A neuron with one axon and one dendrite; primarily in the retina.

Pseudounipolar Neuron

A neuron with one process split into two branches; transmits sensory info from periphery.

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CNS Function

Central Nervous System processes information and transmits signals.

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Presynaptic Terminal

The end part of a neuron where neurotransmitters are released.

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Postsynaptic Receptors

Receptors on a neuron that receive neurotransmitters from the presynaptic terminal.

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Ionotropic Receptors

Receptors that are ion channels, opening or closing rapidly in response to neurotransmitters.

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Metabotropic Receptors

Receptors that use transduction mechanisms and are slower than ionotropic receptors.

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Chemical Signal

A signal primarily consisting of neurotransmitters transmitted across the synaptic cleft.

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Electrical Synapses

Synapses that allow direct and rapid communication via gap junctions.

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Signal Transmission Speed

The rate at which signals are sent across synapses; ionotropic is fast, metabotropic is slow.

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Function of Ionotropic Receptors

They allow quick changes in membrane potential by permitting ion flow.

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Neuroglia

Non-neuronal cells that support, protect, and maintain neurons.

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Astrocytes

Star-shaped glial cells that maintain ionic balance and remove waste.

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Microglia

Phagocytic cells that clear debris and modulate inflammation in the CNS.

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Oligodendrocytes

Glial cells that produce myelin to insulate axons in the CNS.

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Myelin

Fatty substance that surrounds axons for faster signal transmission.

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Nodes of Ranvier

Gaps in myelin that facilitate rapid signal conduction along axons.

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Meninges

Three protective membranes covering the brain and spinal cord.

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Dura Mater

The tough outermost layer of the meninges.

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Arachnoid Mater

The middle layer of the meninges, resembling a spider web.

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Pia Mater

The delicate innermost layer of the meninges that adheres to the brain.

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Dural Sinuses

Spaces formed when the two layers of the dura mater separate.

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Falx Cerebri

A dural reflection that separates the left and right cerebral hemispheres.

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Subarachnoid Space

The area between the arachnoid mater and pia mater filled with CSF.

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Cerebrospinal Fluid (CSF)

Fluid in the subarachnoid space that cushions the brain.

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PICA

Posterior Inferior Cerebellar Artery; first branch of the vertebral artery.

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Circle of Willis

A structure that connects anterior and posterior blood supply in the brain.

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Anterior Cerebral Arteries (ACA)

Supply medial portions of the frontal and parietal lobes of the brain.

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Basilar Artery

Supplies the brainstem, cerebellum, and cervical spinal cord.

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Cerebral Veins

Drain oxygen-depleted blood from the brain to dural sinuses.

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Posterior Communicating Arteries

Connect the internal carotid arteries to the posterior cerebral arteries.

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Internal Carotid Arteries

Supply the anterior two-thirds of the cerebral hemispheres.

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Brainstem

The central part of the brain, controlling vital functions.

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Midbrain

The upper part of the brainstem involved in eye movement and motor coordination.

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Pons

Middle structure of the brainstem that links to cerebellum and houses cranial nerve nuclei.

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Medulla Oblongata

The lowest part of the brainstem responsible for autonomic functions and decussation of tracts.

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Reticular Activating System (RAS)

A network in the brainstem that regulates arousal and consciousness.

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Regulation of Neuronal Activity

Process by which the RAS modulates brain activity using neurotransmitters.

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Olivary Nuclei

Nuclei in the medulla that assist in coordinating movement and sound perception.

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Decussation

The crossing of nerve fibers in the medulla important for sensory and motor function.

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Saltatory Conduction

The process where action potentials jump between nodes of Ranvier in myelinated axons, speeding up transmission.

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Demyelination

The damage or loss of myelin, leading to slowed or blocked nerve signal transmission.

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Action Potential Generation

The process where a large enough ionic flow causes a rapid change in membrane potential, initiating a nerve impulse.

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Resting Potential

The state of a neuron at rest where its inside is negatively charged, ready to fire an action potential.

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Depolarization

The phase in action potential generation where voltage-gated sodium channels open, allowing sodium to flow into the neuron.

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Ion Channels

Proteins in the neuron membrane that allow ions to enter or exit, playing a key role in generating action potentials.

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Central Nervous System (CNS)

Comprises the brain and spinal cord; processes information.

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Peripheral Nervous System (PNS)

Includes cranial and peripheral nerves outside the CNS.

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Upper Motor Neurons

Neurons in the CNS that initiate movement commands.

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Lower Motor Neurons

Neurons in the PNS that directly innervate muscles.

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Myelin Production in CNS

Oligodendrocytes produce myelin for insulation of axons.

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Myelin Production in PNS

Schwann cells create myelin for peripheral axons.

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CNS Protection

CNS is protected by the skull and vertebral column.

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PNS Components

Comprises ganglia and peripheral nerves that transmit signals.

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Neurotransmitters

Signaling molecules that facilitate communication between neurons.

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Acetylcholine

A neurotransmitter essential for muscle contraction in the peripheral nervous system.

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Glutamate

A major excitatory neurotransmitter in the central nervous system, involved in most brain functions.

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GABA

The primary inhibitory neurotransmitter in the brain, slows down nervous system activity.

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Catecholamines

A class of neurotransmitters that can be excitatory or inhibitory, like dopamine and norepinephrine.

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Endocannabinoids

Neurotransmitters released post-synaptically that inhibit neurotransmitter release.

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PCA Damage Effect

Damage to the PCA can cause visual disturbances such as hemianopsia and cortical blindness.

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Cerebellar Artery Functions

Vertebral and basilar arteries control breathing, heart rate, and balance.

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Hemorrhagic Stroke

Occurs when a blood vessel ruptures, causing bleeding in the brain and tissue damage.

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Signs of Stroke

Sudden weakness, vision loss, speech difficulty, severe headaches, and dizziness.

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PICA Stroke Symptoms

Damage to PICA can cause headache, vertigo, and ataxia.

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MCA Stroke Effects

A stroke in the MCA territory affects motor and sensory functions of the face and arm.

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NIH Stroke Scale

A standard neurological exam to assess stroke severity within the first 48 hours.

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Cerebellar Artery Damage Symptoms

Superior Cerebellar Artery damage causes contralateral sensory loss and ipsilateral ataxia.

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Cortical Homunculus

A visual representation of body parts mapped onto the brain's motor and sensory cortices.

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Primary Motor Cortex

Located in the precentral gyrus, it controls voluntary movements.

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Primary Somatosensory Cortex

Located in the postcentral gyrus, processes sensory information from the body.

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Motor Homunculus

A representation showing how areas of the brain correspond to body movements.

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Sensory Homunculus

Maps out sensory responses from different body parts in the somatosensory cortex.

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Cuneus

A wedge-shaped part of the occipital lobe involved in visual processing.

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Limbic Lobe

A C-shaped brain structure associated with memory, emotion, and motivation.

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Olfactory Nerve

The cranial nerve responsible for the sense of smell; originates in the nasal cavity and ends at the olfactory cortex.

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Optic Nerve

The cranial nerve responsible for vision; carries visual information from the retina to the brain.

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Cranial Nerve Lesion Consequences

May result in loss of specific functions such as smell, vision, or movement depending on the affected nerve.

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Olfactory Nerve Testing

To assess the olfactory nerve, a patient is asked to identify familiar scents like coffee or vanilla.

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Optic Nerve Testing

To evaluate the optic nerve, visual acuity is often tested using an eye chart, assessing sight clarity.

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Study Notes

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