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Questions and Answers

What is the role of enterokinase in protein digestion?

  • It absorbs amino acids.
  • It activates pancreatic proteases. (correct)
  • It emulsifies fats.
  • It breaks down starches.

Salivary amylase is responsible for the initial digestion of proteins.

False (B)

What are the end products of fat digestion?

Fatty acids and monoglycerides

Pancreatic amylase breaks down starches into ____________ in the small intestine.

<p>disaccharides</p> Signup and view all the answers

Match the digestive enzymes with their corresponding substrates:

<p>Pepsin = Proteins Pancreatic amylase = Starches Pancreatic lipase = Triglycerides Brush border enzymes = Disaccharides</p> Signup and view all the answers

What is HDL commonly known as?

<p>Good cholesterol (B)</p> Signup and view all the answers

Fatty acids cannot be used by muscle tissue for energy.

<p>False (B)</p> Signup and view all the answers

What effect do high levels of 2,3-DPG have on the oxygen dissociation curve?

<p>It shifts the curve to the right, increasing oxygen release. (A)</p> Signup and view all the answers

The brainstem does not play a role in coordinating breathing.

<p>False (B)</p> Signup and view all the answers

Which tissues can use glucose for energy?

<p>Muscles, fat, and liver cells</p> Signup and view all the answers

HDL helps remove excess cholesterol from the bloodstream and transport it to the _____ for excretion or recycling.

<p>liver</p> Signup and view all the answers

What are two functions of the upper respiratory system when inhaling air?

<p>Warm and filter incoming air.</p> Signup and view all the answers

During exercise, glucose is available for ______ reactions.

<p>aerobic and anaerobic</p> Signup and view all the answers

What happens to insulin levels after a meal?

<p>They increase (A)</p> Signup and view all the answers

What is the primary effect of vasoconstriction on blood pressure?

<p>Increases blood pressure (A)</p> Signup and view all the answers

Which is the main source of ATP during a 100-meter dash?

<p>Phosphocreatine (A)</p> Signup and view all the answers

Aldosterone promotes the excretion of sodium and water in the kidneys.

<p>False (B)</p> Signup and view all the answers

LDL is known to contribute to a lower risk of cardiovascular diseases.

<p>False (B)</p> Signup and view all the answers

The brain primarily uses _____ and ketones for energy.

<p>glucose</p> Signup and view all the answers

Fatty acids can be used for anaerobic metabolism.

<p>False (B)</p> Signup and view all the answers

What stimulates the release of aldosterone from the adrenal glands?

<p>Angiotensin II</p> Signup and view all the answers

The hormone that increases heart rate and the force of cardiac contraction is called ______.

<p>Angiotensin II</p> Signup and view all the answers

Match the following terms with their appropriate definitions:

<p>2,3-DPG = Shifts the oxygen dissociation curve to the right Chemoreceptors = Monitor blood gases and pH levels Upper respiratory system = Conditions and filters inhaled air Muscle ATP = Immediate energy source for muscle contraction</p> Signup and view all the answers

Match the following terms with their descriptions:

<p>HDL = Good cholesterol LDL = Bad cholesterol Insulin = Facilitates glucose uptake Glucagon = Raises blood glucose levels</p> Signup and view all the answers

What adaptation occurs due to high altitudes when 2,3-DPG levels increase?

<p>Increased oxygen release to tissues.</p> Signup and view all the answers

What additional systemic response does ANG II activate to regulate blood pressure?

<p>Sympathetic nervous system (D)</p> Signup and view all the answers

Name one effect of antidiuretic hormone (ADH) on the kidneys.

<p>Promotes water retention</p> Signup and view all the answers

Match each hormone to its primary action:

<p>Aldosterone = Increases sodium and water retention Angiotensin II = Increases blood pressure Antidiuretic Hormone (ADH) = Promotes water retention Norepinephrine = Stimulates vasoconstriction</p> Signup and view all the answers

Vasodilation decreases blood pressure.

<p>True (A)</p> Signup and view all the answers

What is the main effect of increased capillary density on muscle function during training?

<p>Improved nutrient exchange (B)</p> Signup and view all the answers

Training decreases cardiac output during exercise.

<p>False (B)</p> Signup and view all the answers

What role do mitochondria play in training-induced increases in the lactate threshold?

<p>Mitochondria improve the ability to use fatty acids and glucose for energy, delaying the shift to anaerobic metabolism.</p> Signup and view all the answers

Increased ventilation during exercise enhances _______ exchange in the lungs.

<p>oxygen</p> Signup and view all the answers

Match the key components with their respective functions related to training:

<p>Pulmonary diffusion = Enhances oxygen exchange in lungs Capillary density = Improves nutrient exchange in muscles Mitochondrial function = Increases energy production from fatty acids Cardiac output = Increases blood volume pumped per minute</p> Signup and view all the answers

Which of the following is NOT a function of the nephron?

<p>Cardiac output regulation (D)</p> Signup and view all the answers

Secretion in the nephron involves the active transport of substances from the blood into the tubular fluid.

<p>True (A)</p> Signup and view all the answers

List the four distinct functions of the nephron.

<p>Filtration, reabsorption, secretion, excretion</p> Signup and view all the answers

What is the primary function of the juxtaglomerular apparatus in relation to GFR?

<p>Auto-regulate GFR (A)</p> Signup and view all the answers

High GFR leads to the constriction of the afferent arteriole to increase glomerular hydrostatic pressure.

<p>False (B)</p> Signup and view all the answers

What hormone is released in response to low blood pressure to help maintain GFR?

<p>renin</p> Signup and view all the answers

The ______ mechanism helps maintain GFR by adjusting the diameter of the afferent arterioles.

<p>myogenic</p> Signup and view all the answers

Match the following terms with their correct descriptions:

<p>GFR = Rate at which blood is filtered through the glomeruli Juxtaglomerular apparatus = Structure that auto-regulates GFR Afferent arteriole = Blood vessel that supplies the glomerulus Efferent arteriole = Blood vessel that drains the glomerulus</p> Signup and view all the answers

Which of the following effects does renin cause when released?

<p>Constriction of the efferent arteriole (C)</p> Signup and view all the answers

The ascending limb of the loop of Henle has no functional association with the afferent and efferent arterioles.

<p>True (A)</p> Signup and view all the answers

What happens to the GFR when blood pressure decreases?

<p>GFR drops below normal</p> Signup and view all the answers

Flashcards

Pulmonary Diffusion

The process by which oxygen moves from the air in the lungs into the blood.

Capillary Density

The density of capillaries in muscles increases, aiding efficient oxygen and nutrient exchange.

Mitochondrial Function

Mitochondria are the energy powerhouses of cells. More mitochondria enable cells to use oxygen more effectively for energy production.

Cardiac Output

The amount of blood pumped by the heart per minute. Increased cardiac output delivers more oxygen to the muscles.

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Filtration

The process of filtering blood in the glomerulus, separating waste products from essential substances.

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Reabsorption

The process of reclaiming valuable substances like water, glucose, and amino acids from the filtered fluid.

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Secretion

The process of actively moving substances from the blood into the filtrate to be excreted.

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Excretion

The final stage of urine formation, where waste and excess substances are expelled from the body.

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What happens to the oxygen dissociation curve when 2,3-DPG levels are high?

The oxygen dissociation curve shifts to the right, indicating that hemoglobin releases more oxygen at a given partial pressure when 2,3-DPG levels are high.

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Why is the 2,3-DPG mechanism important in hypoxic conditions?

High altitudes, anemia, and lung disease are conditions where oxygen delivery to tissues is compromised. The increased release of oxygen due to elevated 2,3-DPG levels helps the body adapt to these low oxygen environments.

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How do central chemoreceptors contribute to breathing regulation?

Central chemoreceptors in the brainstem are sensitive to changes in blood gases and pH. They send signals to control networks within the brainstem, which in turn adjust the activity of somatic motor neurons responsible for breathing.

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What is the role of peripheral chemoreceptors in breathing?

Peripheral chemoreceptors located in the carotid arteries and aorta are also sensitive to blood gas levels and pH, sending feedback to the brainstem control networks.

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How does the brainstem coordinate breathing?

Control networks in the brainstem, influenced by feedback from central and peripheral chemoreceptors, regulate the activity of somatic motor neurons responsible for breathing.

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What is the role of the upper respiratory system in breathing?

The upper respiratory system (nose, pharynx, and sinuses) functions to warm, humidify, and filter inhaled air, protecting the delicate tissues of the lungs.

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How is glucose used during exercise?

Glucose can be used as an energy source for both aerobic and anaerobic metabolism in muscles during exercise.

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How are fatty acids used during exercise?

Fatty acids are primarily used for aerobic metabolism in muscle during exercise, as anaerobic conditions are not efficient for fatty acid breakdown.

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Glomerular Filtration Rate (GFR)

The process by which the kidneys filter blood and produce urine. A healthy rate of filtration ensures proper blood volume and efficient kidney function.

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Autoregulation of GFR

The automatic regulation of GFR by the kidneys to maintain stable filtration despite changes in blood pressure.

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Juxtaglomerular Apparatus

A specialized structure in the kidney that helps regulate GFR. It consists of the macula densa cells and granular cells.

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Myogenic Mechanism

A mechanism in which the afferent arterioles constrict in response to increased blood pressure to protect the glomerulus from damage.

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Tubuloglomerular Feedback

A type of feedback mechanism within the juxtaglomerular apparatus that helps maintain GFR.

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Macula Densa Cells

Cells in the juxtaglomerular apparatus that detect changes in sodium concentration in the tubular fluid and release paracrines in response.

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Granular Cells

Cells in the juxtaglomerular apparatus that secrete renin, a hormone that helps regulate blood pressure.

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Renin

A hormone released from the granular cells in response to low blood pressure. It helps to constrict the efferent arteriole and raise GFR.

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Zymogens and their activation in the digestive system

Zymogens are inactive enzyme precursors. Trypsinogen is an example of a zymogen secreted by the pancreas. It is activated by enterokinase in the small intestine, preventing the pancreas from self-digesting.

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What role does pepsin play in protein digestion?

Pepsin is a protein-digesting enzyme found in the stomach. It begins the process of breaking down proteins into smaller polypeptides.

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How are proteins broken down in the small intestine?

Pancreatic proteases, like trypsin and chymotrypsin, further breakdown polypeptides into peptides and amino acids in the small intestine. These smaller molecules are then absorbed by the intestinal epithelial cells.

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How is carbohydrate digestion initiated and continued?

Salivary amylase is an enzyme in saliva that begins starch digestion in the mouth. Pancreatic amylase takes over in the small intestine, breaking down starches into disaccharides like maltose.

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What happens to disaccharides in the small intestine?

Brush border enzymes, such as lactase, sucrase, and maltase, are located on the surface of the small intestine's epithelial cells. They break down disaccharides into monosaccharides (like glucose, fructose, and galactose), which are absorbed by the enterocytes.

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Aldosterone

A hormone released by the adrenal cortex that increases sodium and water retention in the kidneys, leading to increased blood volume and blood pressure.

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Aldosterone Action: Binding to MR

A steroid hormone that binds to mineralocorticoid receptors (MR) in the cytoplasm of cells in the DCT and collecting duct.

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Aldosterone Action: Sodium-Potassium Pumps

Aldosterone's binding to MR triggers a series of events that increase the production of sodium-potassium pumps in the nephron cells.

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Aldosterone Action: Water Reabsorption

Aldosterone increases the permeability of the DCT and collecting ducts to water, allowing water to be reabsorbed back into the bloodstream.

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Nephron Function

The process by which the kidneys filter blood, remove waste products, and regulate the volume and composition of bodily fluids.

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Distal Convoluted Tubule (DCT)

The distal convoluted tubule (DCT) is a part of the nephron where aldosterone acts to regulate sodium and water reabsorption.

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Collecting Duct

The collecting duct is a part of the nephron where aldosterone acts to regulate water reabsorption, further contributing to blood pressure regulation.

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Homeostasis

The process by which the kidneys maintain a stable internal environment despite changes in external conditions.

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How are fatty acids transported in the blood?

Fatty acids are transported in the blood bound to albumin, a protein in the blood plasma. They can be utilized by tissues like muscle for beta-oxidation, generating energy, or stored in adipose tissue for future use.

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What is HDL and its role in the body?

HDL, referred to as 'good cholesterol,' helps eliminate excess cholesterol from the bloodstream and transports it to the liver for excretion or recycling. High HDL levels typically correlate with a reduced risk of cardiovascular diseases.

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What is LDL and its role in the body?

LDL, often termed 'bad cholesterol,' carries cholesterol from the liver to peripheral tissues. Excess LDL can deposit cholesterol in the arteries, contributing to atherosclerosis and cardiovascular diseases.

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What happens to blood glucose levels after a meal?

After a meal, blood glucose levels increase, prompting the pancreas to release insulin. Insulin facilitates the uptake of glucose into muscle, fat, and liver cells for energy use or storage as glycogen. This process also inhibits the release of glucagon, a hormone that typically raises blood glucose.

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Which tissues can use glucose, fatty acids, and ketones for energy?

Muscles can use glucose, fatty acids, amino acids, glycerol, and ketones as energy sources. The brain, however, can only use glucose and ketones for energy.

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Describe the physiological response to elevated plasma glucose after a meal?

Elevated plasma glucose levels trigger the release of insulin from the pancreas after a meal. Insulin facilitates the uptake of glucose into muscle, fat, and liver cells, where it can be used for energy or stored as glycogen. The increase in insulin also inhibits the release of glucagon, a hormone that typically raises blood glucose.

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