General Pathology-2: Disorders of Immune Reaction

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39 Questions

Which of the following is defined as a foreign protein that can evoke an immune response mediated by B or T lymphocytes?

Antigen

What is a hapten?

An incomplete antigen

What are the proteins secreted by plasma cells called?

Antibodies

What is the term for body defense mechanisms aiming at disposal of living irritants?

Nonspecific immunity

Which type of immunity involves serum antibodies secreted by plasma cells?

Humoral immunity

What is the term for proteins that help phagocytosis?

Opsonins

From which cells do plasma cells develop?

B lymphocytes

Which of the following is NOT an example of useful antibodies?

Immunoglobulins

What is the term for the secretions of T lymphocytes?

Lymphokines

What is the term for a non-protein foreign substance (e.g. drug) that can evoke an immune response by combining with one of the body proteins?

Hapten

Which of the following is NOT a serum antibody secreted by plasma cells?

IgD

What type of immunity involves lymphokines secreted by stimulated T lymphocytes?

Cell-mediated immunity

Which of the following is a protein secreted by plasma cells?

Immunoglobulin

What term refers to body defense mechanisms aiming at disposal of living irritants?

Phagocytosis

Which of the following is defined as a foreign protein that can evoke an immune response mediated by B or T lymphocytes?

Antigen

What is the term for secretions of T lymphocytes?

Lymphokines

Which of the following is NOT an example of useful antibodies?

Immunoglobulins

Nonspecific immunity includes which of the following?

Natural killer cells

Plasma cells develop from which type of cells?

B lymphocytes

Which type of hypersensitivity involves the production of IgE localized within a certain tissue or organ?

Type I hypersensitivity

What is the main immunoglobulin involved in Type I hypersensitivity reactions?

IgE

Which type of reaction is characterized by the liberation of histamine and other chemical mediators from mast cells?

Type I hypersensitivity

Which condition may manifest as urticaria, bronchospasm, generalized edema, and even shock and death?

Anaphylactic shock

Which type of hypersensitivity reaction involves the activation of macrophages to engulf an organism?

Type IV hypersensitivity

Which type of hypersensitivity reaction is NOT mediated by immunoglobulins but by sensitized T cells?

Type IV hypersensitivity

What distinguishes atopy from anaphylactic shock in terms of IgE production?

Localization of IgE production within a specific tissue or organ

What distinguishes Type IV hypersensitivity from Type I, II, and III in terms of the reaction development time?

It develops over several days

What is the mechanism behind Type I hypersensitivity reactions?

Introduction of antigen stimulates IgE formation, leading to histamine release from mast cells

What are the characteristics of allergic inflammation seen in Type I hypersensitivity reactions?

Excess fluid exudate (oedema) and eosinophils

What is the term for a non-protein foreign substance that can evoke an immune response by combining with one of the body proteins?

Hapten

Which type of immunity involves the secretion of serum antibodies by plasma cells?

Humoral immunity

From which cells do plasma cells develop?

B lymphocytes

Which of the following is NOT a characteristic of nonspecific immunity?

Secretion of serum antibodies by plasma cells

What is the term for proteins secreted by plasma cells?

Immunoglobulins

Which type of hypersensitivity reaction is characterized by the liberation of histamine and other chemical mediators from mast cells?

Type I hypersensitivity

From which cells do plasma cells develop?

B lymphocytes

Which condition may manifest as urticaria, bronchospasm, generalized edema, and even shock and death?

Anaphylactic shock

What distinguishes atopy from anaphylactic shock in terms of IgE production?

Localization of IgE production in atopy

What is the term for body defense mechanisms aiming at disposal of living irritants?

Nonspecific immunity

Test your understanding of the disorders of immune reaction with this quiz based on Dr. Mohammed Abdellah's lecture at Sinai University. Topics include definitions of antigens, auto-antigens, hapten, and immune response mediated by B or T lymphocytes.

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