General IMED Hematology: Bleeding Disorders Quiz
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Questions and Answers

Which factor causes vasoconstriction in the sequence of haemostasis?

  • Von Willebrand factor
  • Thromboxane A2 (correct)
  • Serotonin
  • Fibrin
  • Which pathway leads to the formation of insoluble and permanent fibrin in haemostasis?

  • Platelet plug pathway
  • Extrinsic pathway
  • Vasoconstriction pathway
  • Intrinsic pathway (correct)
  • What leads to the formation of a permanent platelet plug in haemostasis?

  • Myogenic contraction of blood vessels
  • Exposure of collagen in vascular injury (correct)
  • Nerve reflex
  • Release of serotonin
  • What is needed for the repair of the damaged blood vessel in haemostasis?

    <p>Coagulation factors, platelets, vascular endothelium, and blood vessel</p> Signup and view all the answers

    What mechanism prevents hypercoagulability state by increasing fluidity?

    <p>Protein C &amp; S</p> Signup and view all the answers

    Which factor is present in the plasma except factor III?

    <p>Thromboplastin</p> Signup and view all the answers

    What is the normal range for platelet count?

    <p>150,000 - 400,000/mm3</p> Signup and view all the answers

    What platelet count range is associated with clinical petechiae?

    <p>&lt; 50,000-20,000 mm3</p> Signup and view all the answers

    What does a prolonged bleeding time mainly indicate?

    <p>Inadequate platelet function</p> Signup and view all the answers

    Which condition is associated with thrombasthenia?

    <p>Von Willebrand's disease</p> Signup and view all the answers

    What does the Partial Thromboplastin Time (PTT) test measure?

    <p>Intrinsic pathway sensitivity</p> Signup and view all the answers

    What does a prolonged Prothrombin Time (PT) indicate?

    <p>Vitamin K deficiency</p> Signup and view all the answers

    What is the normal range for the Whole Blood Clotting Time test?

    <p>5-10 minutes</p> Signup and view all the answers

    What does an International Normalized Ratio (INR) of 1 indicate?

    <p>&lt; 1 Prothrombin Time</p> Signup and view all the answers

    What is the primary function of haemostasis?

    <p>Prevention of blood loss when a blood vessel is injured</p> Signup and view all the answers

    Which sequence of events occurs first in the process of haemostasis?

    <p>Vasoconstriction</p> Signup and view all the answers

    What leads to the formation of a permanent platelet plug in haemostasis?

    <p>Release of Von Willebrand factor causing platelet adhesion</p> Signup and view all the answers

    What is the role of protein C & S and thrombin III in haemostasis?

    <p>Prevent hypercoagulability state by increasing fluidity</p> Signup and view all the answers

    Which component is NOT needed for the repair of the damaged blood vessel in haemostasis?

    <p>Hemoglobin</p> Signup and view all the answers

    What characterizes any bleeding disorder according to the provided text?

    <p>Defect in coagulation factors</p> Signup and view all the answers

    Which factor is NOT present in the plasma?

    <p>Thromboplastin</p> Signup and view all the answers

    What is the main consequence of a platelet count less than 10,000-20,000 mm3?

    <p>ICU admission</p> Signup and view all the answers

    What is the effect of a prolonged Bleeding Time?

    <p>Reduced platelet function</p> Signup and view all the answers

    In which condition is the platelet count normal but its function unwell?

    <p>Uraemia</p> Signup and view all the answers

    Which factor deficiency can lead to a prolonged Partial Thromboplastin Time (PTT)?

    <p>Factor X</p> Signup and view all the answers

    What does a prolonged Prothrombin Time (PT) indicate?

    <p>Vitamin K deficiency</p> Signup and view all the answers

    Which test measures the efficiency of the extrinsic pathway of coagulation?

    <p>Prothrombin Time (PT)</p> Signup and view all the answers

    In which condition is the Platelet Count range considered adequate for hemostasis?

    <p>$80,000-100,000 mm^3$</p> Signup and view all the answers

    What is the main factor responsible for the formation of a permanent platelet plug in haemostasis?

    <p>Platelet Aggregation</p> Signup and view all the answers

    What does a prolonged Partial Thromboplastin Time (PTT) indicate?

    <p>Factor VIII Deficiency</p> Signup and view all the answers

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