Disorders of the Blood Part 2: Approach to a Bleeding Child
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Questions and Answers

What is the main function of fibrinogen in the hemostatic process?

  • Providing the reaction surface on which clotting reactions occur
  • Acting as a ligand between platelets during platelet aggregation
  • Serving as a substrate for thrombin that forms the fibrin clot (correct)
  • Contracting to constrict and limit clot size

Which factor is measured in the intrinsic (surface activation) pathway of PT PTT tests?

  • Factor VII
  • Factor IX (correct)
  • Factor V
  • Factor X

What is the primary hemostatic mechanism associated with platelet plug formation in the hemostatic process?

  • Fibrin thrombus formation
  • Vasoconstriction
  • Extrinsic pathway
  • Platelet phase (correct)

What is the main function of platelets in the hemostatic process?

<p>Forming the plug at the site of the vessel injury (A)</p> Signup and view all the answers

What is the purpose of the initial lab tests mentioned in the text?

<p>To evaluate the clinical phenotype of bleeding (C)</p> Signup and view all the answers

What is a systematic approach for reaching a more precise clinical diagnosis when evaluating a child with a bleeding disorder?

<p>Obtaining a complete history and physical examination (A)</p> Signup and view all the answers

Which coagulation assays measure the intrinsic and extrinsic pathways?

<p>Activated Partial Thromboplastin Time and Prothrombin Time Tests (B)</p> Signup and view all the answers

What could be inferred from an initial screen showing increased PT and PTT with normal platelet count?

<p>Vitamin K Deficiency or Liver Disease (B)</p> Signup and view all the answers

What is the normal range for Prothrombin Time Tests (PT) mentioned in the text?

<p>10 to 16 seconds (B)</p> Signup and view all the answers

Which of the following is a helpful clinical feature in evaluating bleeding disorders, as per the text?

<p>Menorrhagia (A)</p> Signup and view all the answers

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