General Anesthetic Agents

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Questions and Answers

Which of the following is the primary effect of general anesthetics on the cardiovascular system?

  • Stimulation of respiratory function
  • Decrease in blood pressure (correct)
  • Increase in heart contractility
  • Decrease in plasma noradrenaline concentration

What is the effect of most general anesthetics on respiration?

  • No effect on respiration
  • Depression and increased arterial CO2 (correct)
  • Stimulation and increased arterial CO2
  • Depression and decreased arterial CO2

What is the pharmacological action of general anesthetics on the central nervous system?

  • Increase in consciousness and sensory awareness
  • Stimulation of action potential conduction
  • Activation of respiratory function
  • Inhibition of synaptic transmission (correct)

Which general anesthetic causes an increase in plasma noradrenaline concentration?

<p>Halothane (B)</p> Signup and view all the answers

From which compound is halothane commercially synthesized?

<p>2-chloro-1,1,1-trifluoroethane (B)</p> Signup and view all the answers

Which of the following general anesthetics is known for potentially decreasing blood pressure?

<p>Enflurane (C)</p> Signup and view all the answers

What is the effect of most general anesthetics on respiration?

<p>They increase arterial CO2 levels (A)</p> Signup and view all the answers

Which type of general anesthetic is known for causing a rapid induction with little or no excitement?

<p>Halothane (B)</p> Signup and view all the answers

What is the primary effect of general anesthetics on the cardiovascular system?

<p>Decrease in heart contractility (C)</p> Signup and view all the answers

Which general anesthetic is an exception in terms of its effect on respiration?

<p>Nitrous oxide (C)</p> Signup and view all the answers

What is the primary effect of general anesthetics on the cardiovascular system?

<p>Decrease in blood pressure (B)</p> Signup and view all the answers

Which general anesthetic is synthesized from trichloroethylene and bromine?

<p>Chloroform (A)</p> Signup and view all the answers

Which type of general anesthetic is known for causing rapid induction with little or no excitement?

<p>Inhalation anesthetics (D)</p> Signup and view all the answers

What effect do most general anesthetics have on respiration?

<p>Depression of respiration (B)</p> Signup and view all the answers

Which general anesthetic is known for potentially increasing plasma noradrenaline concentration and thereby leading to an increase in blood pressure?

<p>Enflurane (A)</p> Signup and view all the answers

Flashcards

Effect of General Anesthetics on BP

General anesthetics primarily cause a decrease in blood pressure.

General Anesthetics & Respiration

Most general anesthetics lead to depression of respiration and increased arterial CO2 levels.

Anesthetics Mechanism in the CNS

General anesthetics inhibit synaptic transmission in the CNS.

Halothane & Noradrenaline

Halothane can cause an increase in plasma noradrenaline concentration.

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Halothane Synthesis

Halothane is synthesized from 2-chloro-1,1,1-trifluoroethane.

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Enflurane's Effect on Blood Pressure

Enflurane is known for its potential to decrease blood pressure.

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Anesthetics effect on Arterial CO2

Most general anesthetics increase arterial CO2 levels.

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Halothane Induction

Halothane is known for causing rapid induction with little or no excitement.

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Anesthetics Effect on Heart

General anesthetics typically decrease heart contractility.

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Nitrous Oxide & Respiration

Nitrous oxide is an exception to the typical effect of general anesthetics on respiration.

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Chloroform Synthesis

Chloroform is synthesized from trichloroethylene and bromine.

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Inhalation Anesthetics & Induction

Inhalation anesthetics are known for causing rapid induction with little or no excitement.

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Anesthetics & Respiration

Most general anesthetics depress respiration.

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Enflurane & Noradrenaline Levels

Enflurane can increase plasma noradrenaline concentration.

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Study Notes

General Anesthetics and Cardiovascular System

  • The primary effect of general anesthetics on the cardiovascular system is a decrease in blood pressure.
  • One exception is ketamine, which can increase blood pressure due to increased plasma noradrenaline concentration.

General Anesthetics and Respiration

  • Most general anesthetics depress respiration, leading to a decrease in respiratory rate.
  • One exception is ketamine, which does not depress respiration.

General Anesthetics and Central Nervous System

  • The pharmacological action of general anesthetics on the central nervous system is to depress the nervous system.

Characteristics of General Anesthetics

  • Barbiturates are known for causing rapid induction with little or no excitement.
  • Halothane is commercially synthesized from a compound.
  • Halothane is synthesized from trichloroethylene and bromine.

Effects of Specific General Anesthetics

  • Ketamine is an exception in terms of its effect on respiration, as it does not depress respiration.
  • Ketamine can increase plasma noradrenaline concentration, leading to an increase in blood pressure.
  • Most general anesthetics, except for ketamine, decrease blood pressure.

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