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Gene Expression and Regulation Quiz

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Questions and Answers

What is the name of the gene associated with familial platelet disorder with myeloid malignancy?

BCOR
RUNX1 (correct)
RUNX2
PRC1.1

Which of the following genes is involved in epigenetic regulation in human embryonic stem cells?

BCOR (correct)
RUNX1
PRC1.1
MEG1

What is the name of the classification system used for myelodysplastic syndromes based on clinical and genomic features?

Genomic Landscape Classification
Clinical and Biological Implications System
Unified Classification System
Molecular International Prognostic Scoring System (correct)

Which of the following studies focused on the genomic landscape of patients with germline RUNX1 variants?

Yu et al. (C) Signup and view all the answers

What is the role of the BCOR-PRC1.1 complex in human embryonic stem cells?

Repressing differentiation programs (A) Signup and view all the answers

Which of the following genes is associated with myeloid neoplasms?

RUNX1 (C) Signup and view all the answers

What is the main purpose of the Molecular International Prognostic Scoring System?

Predicting prognosis in myelodysplastic syndromes (A) Signup and view all the answers

Which of the following studies validated the Molecular International Prognostic Scoring System in real-world settings?

Sauta et al. (B) Signup and view all the answers

What is the role of chromosomal abnormalities in myelodysplastic syndromes?

Contributing to disease prognosis (A) Signup and view all the answers

Which of the following genes is involved in the development of cancer?

BCOR (C) Signup and view all the answers