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Gender Differences in Disease Risk

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Questions and Answers

Why should future research focus on improving the effectiveness of immunotherapies in women?

Men have higher resistance to immunotherapy

Women are more responsive to immunotherapy

Tumor suppressor genes are more highly expressed in women (correct)

Women are less affected by tumor suppressor gene mutations

How do females potentially benefit regarding tumor suppressor genes compared to males?

Females have a single copy of the X chromosome

Females have a double dose of tumor suppressors due to two X chromosomes (correct)

Males have a double dose of tumor suppressors due to two X chromosomes

Males have a single copy of the X chromosome

What has emerged as pivotal in orchestrating host defense in NSCLC?

Estrogen production

IFN type II (IFN-II)

Testosterone signaling

IFN type I (IFN-I) (correct)

Why do females have a backup copy of tumor suppressor genes?

One copy remains functional on the second X chromosome Signup and view all the answers

In which condition are tumor suppressor genes more highly expressed in females than in males?

Lung cancer (NSCLC) Signup and view all the answers

What could be a strategy to enhance the effectiveness of immunotherapies in men according to the text?

Exploring different immunotherapeutic approaches Signup and view all the answers

What is the effect of being a woman on the risk of developing dementia?

Being a woman is a risk factor for dementia Signup and view all the answers

How does the risk of women suffering from Alzheimer's disease compare to that of men?

Women have almost twice the risk of men Signup and view all the answers

In terms of stroke, what percentage of risks are faced by females compared to males?

55% Signup and view all the answers

Which factor is more detrimental in producing risk: cigarettes in women or men?

Cigarettes in women produce more risk Signup and view all the answers

What effect does hypertension have on women?

Hypertension is more dangerous for women at higher levels Signup and view all the answers

Which group has higher mortality rates in cancer according to the text?

Men Signup and view all the answers