Gastrointestinal Therapeutics 2
39 Questions
0 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What could be a possible cause for reduced appetite in cats?

  • Increased physical activity
  • Higher than normal food intake
  • Chronic inflammatory diseases (correct)
  • Fever from viral infections

    • Which drug principle is essential when treating gastrointestinal disease?

  • Use of broad-spectrum antibiotics only
  • Modification of gastrointestinal flora (correct)
  • Direct inhibition of gastrointestinal motility
  • Stimulation of appetite regardless of disease

    • What can excessive appetite in domesticated species indicate?

  • An underlying behavioral issue
  • Malnutrition or undernutrition
  • Obesity-related health problems (correct)
  • Normal metabolic processes

    • What is a key pharmacological principle of antiparasitic treatments?

    <p>They should act selectively against parasites</p> Signup and view all the answers

    Which of these is NOT a common reason for gastrointestinal dysfunction in domesticated species?

    <p>Increase in dietary fibers</p> Signup and view all the answers

    What is the primary mechanism of action for metronidazole?

    <p>Inhibits nucleic acid function</p> Signup and view all the answers

    Which of the following is NOT a characteristic of Acute Haemorrhagic Diarrhoea Syndrome (HGE)?

    <p>Low plasma proteins</p> Signup and view all the answers

    Which broad-spectrum anthelmintic should be classified as a prodrug?

    <p>Febantel</p> Signup and view all the answers

    What is a common treatment approach for Acute Haemorrhagic Diarrhoea Syndrome?

    <p>Aggressive symptomatic/supportive care</p> Signup and view all the answers

    What is the effect of benzimidazoles on parasites?

    <p>Inhibits glucose uptake and causes glycogen depletion</p> Signup and view all the answers

    Which of the following statements is true regarding benzimidazoles?

    <p>Prolonged exposure increases the efficacy of benzimidazoles.</p> Signup and view all the answers

    What distinguishes triclabendazole from other benzimidazoles?

    <p>It is effective against early immature stages of Fasciola hepatica.</p> Signup and view all the answers

    What is the role of nicotinic agonists in parasitology?

    <p>They induce rapid and reversible muscle paralysis.</p> Signup and view all the answers

    Which age should puppies and kittens be dosed with fenbendazole?

    <p>At 2, 5, 8, and 12 weeks of age.</p> Signup and view all the answers

    Which drug is known for being effective against late immature stages of parasites?

    <p>Nitroxynil.</p> Signup and view all the answers

    Which class of drugs is selective for nematode muscles?

    <p>Imidazothiazoles</p> Signup and view all the answers

    What effect do macrocyclic lactones have on nematodes?

    <p>Hyperpolarisation and flaccid paralysis</p> Signup and view all the answers

    What is praziquantel primarily used for?

    <p>To cause severe damage to the parasite integument</p> Signup and view all the answers

    Which agent inhibits folate synthesis in protozoa?

    <p>Trimethoprim/sulphonamide (TMPS)</p> Signup and view all the answers

    What compound classification does ivermectin belong to?

    <p>Macrocyclic Lactones</p> Signup and view all the answers

    Which drug is specifically mentioned as having persistent activity for preventative worm strategies?

    <p>Ivermectin</p> Signup and view all the answers

    What is believed to be the mechanism of action for praziquantel?

    <p>Changes in divalent cation fluxes</p> Signup and view all the answers

    Which drug class includes pyrantel?

    <p>Tetrahydropyrimidines</p> Signup and view all the answers

    Which appetite stimulant is known for having effects typically seen within 30 minutes?

    <p>mirtazapine</p> Signup and view all the answers

    What is a characteristic of probiotics?

    <p>They are live microorganisms that confer health benefits.</p> Signup and view all the answers

    Which appetite stimulant is a ghrelin agonist and was recently approved?

    <p>capromorelin</p> Signup and view all the answers

    What approach is NOT recommended for encouraging a cat to eat?

    <p>Offering food for an extended period</p> Signup and view all the answers

    What is the primary reason for anorexia in pets?

    <p>Usually secondary to another condition</p> Signup and view all the answers

    Which of the following is a common endoparasite?

    <p>Cestodes</p> Signup and view all the answers

    In terms of gastrointestinal health, what is the role of prebiotics?

    <p>They support beneficial microorganisms through selective fermentation.</p> Signup and view all the answers

    Why should the use of diazepam as an appetite stimulant be avoided?

    <p>It carries a high risk of acute hepatic necrosis.</p> Signup and view all the answers

    Which drug is commonly used as an appetite stimulant with anti-nausea effects?

    <p>Mirtazapine</p> Signup and view all the answers

    What is the primary action of benzimidazoles in treating gastrointestinal diseases?

    <p>Binding to parasite tubulin</p> Signup and view all the answers

    Which condition is metronidazole NOT used to treat?

    <p>Dermatophytosis</p> Signup and view all the answers

    Which type of anthelmintic is levamisole classified as?

    <p>Nicotinic agonist</p> Signup and view all the answers

    What is a potential consequence of irresponsible use of anthelmintics?

    <p>Development of drug resistance</p> Signup and view all the answers

    Which of the following is NOT a characteristic of metronidazole?

    <p>Has no anti-inflammatory effects</p> Signup and view all the answers

    What role does intestinal microbiota play in gastrointestinal health?

    <p>Helping to maintain GI homeostasis</p> Signup and view all the answers

    Which drug is considered safe for use in puppies and lactating bitches?

    <p>Fenbendazole</p> Signup and view all the answers

    Study Notes

    Gastrointestinal Therapeutics 2

    • The presentation is about gastrointestinal therapeutics in veterinary pharmacology and therapeutics.
    • Learning outcomes include identifying drugs to modify GI function, understanding pharmacological principles of GI disease treatments, and examples of drug use for common diseases in domesticated animals. Treatments for appetite problems and intestinal microbiota as well as endoparasitism are also covered.
    • Appetite stimulants include mirtazapine, a noradrenaline and serotonergic antagonist with appetite-stimulant, anti-emetic, and anti-nausea effects, typically seen within 30 minutes. Cyproheptadine, a non-selective serotonergic antagonist, can take up to 24 hours to be effective. Diazepam, historically used as an appetite stimulant, should be avoided due to potential acute hepatic necrosis risk. Capromorelin, a ghrelin agonist, was recently approved.
    • Drugs used to treat digestive issues include appetite modifiers for reduced or excessive appetite, intestinal microbiota imbalances, and endoparasites like nematodes, cestodes, and Giardia.
    • Anorexia is usually secondary to other conditions such as various body system-related issues, inflammatory responses, infections, and chemotherapy.
    • Intestinal microbiota consists of bacterial communities that outnumber host cells by tenfold, typically playing beneficial roles in the gut. Imbalances can cause conditions such as chronic enteropathy, exocrine pancreatic insufficiency, antibiotic responsive diarrhea, motility disturbances, or specific infectious agents.
    • Antibiotic restrictions are crucial for digestive disease treatment, including those in hemorrhagic diarrhea, ARD, or SIBO. Metronidazole, a common drug, is bactericidal against many Gram-positive and Gram-negative anaerobic bacteria, and it also has antiprotozoal and anti-inflammatory properties.
    • Acute hemorrhagic diarrhea syndrome (HGE), a condition where the cause is uncertain but likely associated with a toxin produced by Clostridium perfringens, typically involves bloody diarrhea and vomiting, causing dehydration, tachycardia, and possible shock. Treatment primarily involves aggressive supportive care like IV fluids, antiemetics, and antibiotics (but use is controversial).
    • Broad spectrum anthelmintics are classified and categorized in various groups. The classification system features different color codes for each group ( 1 - BZ, 2 - LV, 3 - ML, 4 - AD, 5 - SI) which are then color-coded accordingly.

    Anthelmintics in Ruminants – Sheep

    • The table details the efficacy of broad and narrow-spectrum anthelmintics against different worm types in sheep.

    Anthelmintics in Ruminants – Cattle

    • The table provides a summary of the efficacy of broad and narrow-spectrum anthelmintics against different worm types in cattle.

    Anthelmintics in Horses

    • Shows which anthelmintics are effective against various parasites in horses including adult and larval stages.

    Studying That Suits You

    Use AI to generate personalized quizzes and flashcards to suit your learning preferences.

    Quiz Team

    Related Documents

    Gastrointestinal Therapeutics 2 PDF

    Description

    This quiz focuses on gastrointestinal therapeutics in veterinary pharmacology and therapeutics. You'll identify drugs that modify GI function, understand pharmacological principles behind treatments for common diseases, and explore examples of appetite stimulants and other medications used in domesticated animals.

    More Like This

    Use Quizgecko on...
    Browser
    Open
    Browser
    Browser