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Questions and Answers
What is the main difference between Crohn’s disease (CD) and ulcerative colitis (UC)?
What is the main difference between Crohn’s disease (CD) and ulcerative colitis (UC)?
- UC affects any part of the GI tract, while CD is confined to the rectum and colon
- UC is caused by genetic factors, while CD is caused by environmental factors
- UC is confined to the rectum and colon, while CD can affect any part of the GI tract from mouth to anus (correct)
- UC is a transmural inflammation of the GI tract, while CD is a mucosal inflammatory condition
What are some contributing factors to the continuing inflammation of the GI mucosa in IBD?
What are some contributing factors to the continuing inflammation of the GI mucosa in IBD?
- High intake of vitamin C and fiber
- Regular physical exercise and adequate sleep
- Excessive consumption of spicy food and caffeine
- Defects in the intestinal epithelial barrier and immune system (correct)
Which of the following is associated with improvement in UC symptoms but worsens CD?
Which of the following is associated with improvement in UC symptoms but worsens CD?
- NSAIDs
- Smoking (correct)
- Luminal bacteria
- Dietary antigens
What are some of the proinflammatory cytokines contributing to the ongoing inflammatory process in IBD?
What are some of the proinflammatory cytokines contributing to the ongoing inflammatory process in IBD?
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What is the genetic association with respect to first-degree relatives of affected patients?
What is the genetic association with respect to first-degree relatives of affected patients?
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