Questions and Answers
What is the main difference between Crohn’s disease (CD) and ulcerative colitis (UC)?
UC is confined to the rectum and colon, while CD can affect any part of the GI tract from mouth to anus
What are some contributing factors to the continuing inflammation of the GI mucosa in IBD?
Defects in the intestinal epithelial barrier and immune system
Which of the following is associated with improvement in UC symptoms but worsens CD?
Smoking
What are some of the proinflammatory cytokines contributing to the ongoing inflammatory process in IBD?
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What is the genetic association with respect to first-degree relatives of affected patients?
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