26 Questions
What is the primary limitation of ulcerative colitis?
It is limited to the colon
What is the primary goal of Inflammatory Bowel Disease treatment?
To resolve acute episodes and prolong remission
What is the mechanism of action of corticosteroids in Inflammatory Bowel Disease?
Inhibition of inflammatory pathways
What is the primary indication for Infliximab in Inflammatory Bowel Disease?
Active and chronic symptoms refractory to corticosteroids
What is the potential benefit of Aminosalicylates in Inflammatory Bowel Disease?
Reduction of risk of colorectal cancer
What is the primary precaution when using Aminosalicylates in Inflammatory Bowel Disease?
Caution in renal impairment, pregnancy, and breast feeding
What is the probable cause of diarrhea due to toxins?
All of the above
What is the primary mechanism of action of anti-diarrheal agents?
Reduce peristalsis by stimulating opioid receptors
What is the contraindication for diphenoxylate/atropine?
All of the above
What is the primary cause of antibiotic-associated diarrhea (AAD)?
Clostridium difficile
What is the mechanism of action of simethicone?
Alters elasticity of mucus-coated bubbles
What is the site of stimulation for antiemetics like scopolamine?
Area postrema
What is the side effect of phenothiazines?
All of the above
What is the therapeutic site of action for ondansetron?
Serotonin 5-HT3 receptors
What is the primary indication for treatment of diarrhea?
All of the above
What is the site of colonization of Clostridium difficile?
Distal aspect of the colon
What is the mechanism of action of Azathioprine?
Inhibition of ribonucleotide synthesis
What is the primary adverse effect of Cyclosporin?
Renal impairment
What is the mechanism of action of Infliximab?
Inhibition of TNF-α
What is the primary goal of treatment for constipation?
To increase bowel content and volume
What type of laxatives are effective in 1-3 hours and are used to purge the intestine?
Osmotic laxatives
What is the primary cause of constipation in laxative abuse?
Enteral loss of water and salts
What is the effect of Lubiprostone on the gut?
It stimulates chloride channels, producing chloride-rich secretions
What is the common adverse effect of Methotrexate?
Hepatotoxicity
What is the role of NFAT proteins in the regulation of T-cell activation?
They are involved in the transcription of interleukin 2
What is the common side effect of Thiopurines?
Flu-like symptoms
Test your knowledge of inflammatory bowel disease, including ulcerative colitis and Crohn's disease, and their treatment options. Learn about the symptoms, diagnosis, and management of these conditions.
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