Gastrointestinal Pharmacology: Inflammatory Bowel Disease
26 Questions
1 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the primary limitation of ulcerative colitis?

  • It is limited to the colon (correct)
  • It is a patchy transmural inflammation
  • It can affect any part of the GI tract
  • It causes only abdominal pain

What is the primary goal of Inflammatory Bowel Disease treatment?

  • To reduce the risk of colorectal cancer
  • To cure the disease
  • To resolve chronic symptoms
  • To resolve acute episodes and prolong remission (correct)

What is the mechanism of action of corticosteroids in Inflammatory Bowel Disease?

  • Expression of pro-inflammatory proteins
  • Inhibition of inflammatory pathways (correct)
  • Enhancement of arachidonic acid metabolism
  • Stimulation of inflammatory pathways

What is the primary indication for Infliximab in Inflammatory Bowel Disease?

<p>Active and chronic symptoms refractory to corticosteroids (C)</p> Signup and view all the answers

What is the potential benefit of Aminosalicylates in Inflammatory Bowel Disease?

<p>Reduction of risk of colorectal cancer (A)</p> Signup and view all the answers

What is the primary precaution when using Aminosalicylates in Inflammatory Bowel Disease?

<p>Caution in renal impairment, pregnancy, and breast feeding (C)</p> Signup and view all the answers

What is the probable cause of diarrhea due to toxins?

<p>All of the above (D)</p> Signup and view all the answers

What is the primary mechanism of action of anti-diarrheal agents?

<p>Reduce peristalsis by stimulating opioid receptors (A)</p> Signup and view all the answers

What is the contraindication for diphenoxylate/atropine?

<p>All of the above (D)</p> Signup and view all the answers

What is the primary cause of antibiotic-associated diarrhea (AAD)?

<p>Clostridium difficile (B)</p> Signup and view all the answers

What is the mechanism of action of simethicone?

<p>Alters elasticity of mucus-coated bubbles (C)</p> Signup and view all the answers

What is the site of stimulation for antiemetics like scopolamine?

<p>Area postrema (C)</p> Signup and view all the answers

What is the side effect of phenothiazines?

<p>All of the above (D)</p> Signup and view all the answers

What is the therapeutic site of action for ondansetron?

<p>Serotonin 5-HT3 receptors (A)</p> Signup and view all the answers

What is the primary indication for treatment of diarrhea?

<p>All of the above (D)</p> Signup and view all the answers

What is the site of colonization of Clostridium difficile?

<p>Distal aspect of the colon (A)</p> Signup and view all the answers

What is the mechanism of action of Azathioprine?

<p>Inhibition of ribonucleotide synthesis (B)</p> Signup and view all the answers

What is the primary adverse effect of Cyclosporin?

<p>Renal impairment (B)</p> Signup and view all the answers

What is the mechanism of action of Infliximab?

<p>Inhibition of TNF-α (B)</p> Signup and view all the answers

What is the primary goal of treatment for constipation?

<p>To increase bowel content and volume (C)</p> Signup and view all the answers

What type of laxatives are effective in 1-3 hours and are used to purge the intestine?

<p>Osmotic laxatives (D)</p> Signup and view all the answers

What is the primary cause of constipation in laxative abuse?

<p>Enteral loss of water and salts (C)</p> Signup and view all the answers

What is the effect of Lubiprostone on the gut?

<p>It stimulates chloride channels, producing chloride-rich secretions (B)</p> Signup and view all the answers

What is the common adverse effect of Methotrexate?

<p>Hepatotoxicity (C)</p> Signup and view all the answers

What is the role of NFAT proteins in the regulation of T-cell activation?

<p>They are involved in the transcription of interleukin 2 (C)</p> Signup and view all the answers

What is the common side effect of Thiopurines?

<p>Flu-like symptoms (D)</p> Signup and view all the answers

More Like This

Use Quizgecko on...
Browser
Browser