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Gastrointestinal Pharmacology: Inflammatory Bowel Disease

This quiz covers the fundamentals of Inflammatory Bowel Disease, including Ulcerative Colitis and Crohn's Disease, as well as treatment options for acute episodes and remission. Topics include symptoms, therapeutics, and pharmacology.

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@SuperiorLorentz
1/26
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Questions and Answers

What is the primary characteristic that distinguishes Crohn's disease from ulcerative colitis?

Patchy transmural inflammation

What is the primary goal of treatment in inflammatory bowel disease?

Resolving acute episodes

Which thiopurine is used to treat active and chronic symptoms of inflammatory bowel disease?

Methotrexate

What is the primary mechanism of action of corticosteroids in inflammatory bowel disease?

<p>Inhibition of inflammatory pathways</p> Signup and view all the answers

What is the name of the antibody infusion used to treat active and chronic symptoms of inflammatory bowel disease?

<p>Infliximab</p> Signup and view all the answers

What is the potential benefit of using aminosalicylates in inflammatory bowel disease?

<p>Reducing the risk of colorectal cancer</p> Signup and view all the answers

What is the primary mechanism of action of loperamide in treating diarrhea?

<p>Stimulating opioid receptors in the bowel</p> Signup and view all the answers

What is the primary cause of antibiotic-associated diarrhea and colitis?

<p>Clostridium difficile</p> Signup and view all the answers

What is the primary action of simethicone in treating flatulence?

<p>Altering the elasticity of mucus-coated bubbles</p> Signup and view all the answers

What is the primary mechanism of action of Azathioprine and mercaptopurine?

<p>Inhibition of ribonucleotide synthesis</p> Signup and view all the answers

What is the primary site of action of antiemetics such as scopolamine?

<p>Area postrema</p> Signup and view all the answers

Which immunosuppressant is metabolized to mercaptopurine and 6-thioguanine nucleotides?

<p>Azathioprine</p> Signup and view all the answers

What is the primary mechanism of action of metoclopramide in treating nausea and vomiting?

<p>Antagonizing dopamine D2 receptors</p> Signup and view all the answers

What is the primary use of ondansetron in treating nausea and vomiting?

<p>Chemotherapy-induced nausea and vomiting</p> Signup and view all the answers

What is the primary mechanism of action of Methotrexate?

<p>Inhibition of dihydrofolate reductase</p> Signup and view all the answers

What is the primary mechanism of action of Cyclosporin?

<p>Inhibition of T cell activation</p> Signup and view all the answers

What is the primary action of diphenoxylate in treating diarrhea?

<p>Slowing intestinal contractions</p> Signup and view all the answers

What is the primary contraindication for the use of metoclopramide?

<p>Parkinson's disease</p> Signup and view all the answers

What is the primary mechanism of action of Infliximab?

<p>Neutralization of TNF-α</p> Signup and view all the answers

What is the primary effect of osmotic laxatives?

<p>Draw fluid into the bowel by osmotic force</p> Signup and view all the answers

What is the primary mechanism of action of phenothiazines in treating nausea and vomiting?

<p>Histamine H1 receptor antagonism</p> Signup and view all the answers

What is the primary effect of bulk agents?

<p>Increase bowel content and volume</p> Signup and view all the answers

What is the primary use of meclizine in treating nausea and vomiting?

<p>Motion sickness</p> Signup and view all the answers

What is the primary effect of stimulant laxatives?

<p>Increase intestinal motility</p> Signup and view all the answers

What is the primary complication of laxative abuse?

<p>Hypokalemia</p> Signup and view all the answers

What is the primary mechanism of action of Lubiprostone?

<p>Stimulation of chloride channels</p> Signup and view all the answers

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