Gastrointestinal Medications Mechanism of Action Quiz

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What is the mechanism of action of Vedolizumab?

Reversibly inhibits α4β7 interaction with MAdCAM-1 on endothelial cells

What is the mechanism of action of Metronidazole?

Induces formation of ROS, inhibits protein synthesis, and causes DNA damage

What is the mechanism of action of Sulfasalazine?

Broken down by intestinal bacteria into 5-ASA or mesalamine

What is the mechanism of action of Infiximab?

Binds to TNFα and prevents binding to TNF receptors

What is the mechanism of action of Loperamide?

Binds to μ-opioid receptor on gut wall and inhibits Ach & PG release

What is the mechanism of action of Vedolizumab?

Reversibly inhibits α4β7 interaction with MAdCAM-1 on endothelial cells

What is the mechanism of action of Infiximab?

Binds to TNFα and prevents binding to TNF receptors

What is the mechanism of action of Metronidazole?

Prodrug that undergoes reduction to form highly active metabolite nitro-radical anion

What is the mechanism of action of Sulfasalazine?

Prodrug that undergoes reduction to form highly active metabolite nitro-radical anion

What is the mechanism of action of Loperamide?

μ-opioid receptor agonist that binds to μ-opioid receptor on gut wall and inhibits Ach & PG rel.

Test your knowledge of gastrointestinal medications and their mechanisms of action with this quiz. Identify the drug class and match it with its respective mechanism of action. From H2RA and PPI to Infiximab and Metronidazole, see how well you know the pharmacology of these medications.

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