Gastrointestinal Medications Mechanism of Action Quiz
10 Questions
1 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the mechanism of action of Vedolizumab?

  • Binds to TNFα and prevents binding to TNF receptors
  • Reduces cAMP and attenuates protein kinases stimulation on H+/K+ ATPase
  • Reversibly inhibits α4β7 interaction with MAdCAM-1 on endothelial cells (correct)
  • Irreversibly inhibits H+/K+ ATPase and antagonizes all stimulants of gastric secretion

What is the mechanism of action of Metronidazole?

  • Reversibly inhibits α4β7 interaction with MAdCAM-1 on endothelial cells
  • Reduces cAMP and attenuates protein kinases stimulation on H+/K+ ATPase
  • Binds to TNFα and prevents binding to TNF receptors
  • Induces formation of ROS, inhibits protein synthesis, and causes DNA damage (correct)

What is the mechanism of action of Sulfasalazine?

  • Binds to TNFα and prevents binding to TNF receptors
  • Broken down by intestinal bacteria into 5-ASA or mesalamine (correct)
  • Reversibly inhibits α4β7 interaction with MAdCAM-1 on endothelial cells
  • Reduces cAMP and attenuates protein kinases stimulation on H+/K+ ATPase

What is the mechanism of action of Infiximab?

<p>Binds to TNFα and prevents binding to TNF receptors (B)</p> Signup and view all the answers

What is the mechanism of action of Loperamide?

<p>Binds to μ-opioid receptor on gut wall and inhibits Ach &amp; PG release (C)</p> Signup and view all the answers

What is the mechanism of action of Vedolizumab?

<p>Reversibly inhibits α4β7 interaction with MAdCAM-1 on endothelial cells (B)</p> Signup and view all the answers

What is the mechanism of action of Infiximab?

<p>Binds to TNFα and prevents binding to TNF receptors (A)</p> Signup and view all the answers

What is the mechanism of action of Metronidazole?

<p>Prodrug that undergoes reduction to form highly active metabolite nitro-radical anion (B)</p> Signup and view all the answers

What is the mechanism of action of Sulfasalazine?

<p>Prodrug that undergoes reduction to form highly active metabolite nitro-radical anion (C)</p> Signup and view all the answers

What is the mechanism of action of Loperamide?

<p>μ-opioid receptor agonist that binds to μ-opioid receptor on gut wall and inhibits Ach &amp; PG rel. (D)</p> Signup and view all the answers

More Like This

Gastrointestinal and Urological Medications Quiz
40 questions

Gastrointestinal and Urological Medications Quiz

HumorousNephrite7817 avatar
HumorousNephrite7817
Gastrointestinal Medications and Side Effects
12 questions

Gastrointestinal Medications and Side Effects

HardyAestheticism avatar
HardyAestheticism
Gastrointestinal Medications Quiz
15 questions

Gastrointestinal Medications Quiz

BoundlessObsidian4130 avatar
BoundlessObsidian4130
Pharmacology: Gastrointestinal Medications
24 questions

Pharmacology: Gastrointestinal Medications

LionheartedBrazilNutTree avatar
LionheartedBrazilNutTree
Use Quizgecko on...
Browser
Open
Browser
Browser