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Questions and Answers
What characterizes functional constipation?
What characterizes functional constipation?
Which factor does NOT lead to secondary constipation?
Which factor does NOT lead to secondary constipation?
What is a common cause of osmotic diarrhea?
What is a common cause of osmotic diarrhea?
Which of the following medications is likely to contribute to constipation?
Which of the following medications is likely to contribute to constipation?
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How does opioid-induced constipation occur?
How does opioid-induced constipation occur?
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Which of the following is a characteristic of slow transit constipation (STC)?
Which of the following is a characteristic of slow transit constipation (STC)?
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Which condition is commonly associated with impaired bowel coordination, leading to constipation?
Which condition is commonly associated with impaired bowel coordination, leading to constipation?
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Exposure to which of the following can lead to secretory diarrhea?
Exposure to which of the following can lead to secretory diarrhea?
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Which lifestyle choice is a risk factor for constipation?
Which lifestyle choice is a risk factor for constipation?
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What is the primary pathophysiological mechanism for diarrhea?
What is the primary pathophysiological mechanism for diarrhea?
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Which medication is least likely to cause decreased bowel motility?
Which medication is least likely to cause decreased bowel motility?
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Which condition is associated with neurological disruption of bowel motility?
Which condition is associated with neurological disruption of bowel motility?
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What dietary factor can contribute to the development of constipation?
What dietary factor can contribute to the development of constipation?
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Which of the following is true about the transmission of constipation?
Which of the following is true about the transmission of constipation?
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What structural issue can lead to difficulty in stool expulsion?
What structural issue can lead to difficulty in stool expulsion?
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Which risk factor is NOT associated with constipation?
Which risk factor is NOT associated with constipation?
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What characterizes osmotic diarrhea?
What characterizes osmotic diarrhea?
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Which condition is primarily associated with secretory diarrhea?
Which condition is primarily associated with secretory diarrhea?
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What is a common risk factor for infectious diarrhea?
What is a common risk factor for infectious diarrhea?
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Which option correctly reflects the pathophysiological mechanism of osmotic diarrhea?
Which option correctly reflects the pathophysiological mechanism of osmotic diarrhea?
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Which statement about secretory diarrhea is true?
Which statement about secretory diarrhea is true?
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What type of diarrhea is associated with non-transmissible conditions?
What type of diarrhea is associated with non-transmissible conditions?
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What is the expected stool volume in osmotic diarrhea?
What is the expected stool volume in osmotic diarrhea?
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How can direct transmission of infectious diarrhea occur?
How can direct transmission of infectious diarrhea occur?
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Study Notes
Gastrointestinal - Diarrhea
- Diarrhea is an increase in stool frequency, volume, or fluid content.
- It can be osmotic or secretory, based on underlying mechanisms.
Osmotic Diarrhea
- Caused by poorly absorbed substances (e.g., lactose, sorbitol) pulling water into the intestines.
- Stool volume is typically less than 1 liter per day.
- Symptoms improve with fasting.
- Can be caused by conditions like celiac disease or bacterial overgrowth (from antibiotics).
Secretory Diarrhea
- Caused by disruptions in electrolyte transport in intestinal cells.
- Excessive water and electrolyte loss occurs.
- Stool volume is usually greater than 1 liter per day.
- Symptoms persist even with fasting.
- Bacteria like E. coli, Vibrio cholerae (cholera toxin), and some viruses can cause it, as well as hormone-producing tumors and certain medications.
Disease Transmission
- Infectious diarrhea (e.g., cholera, rotavirus, E. coli) is spread through contaminated food/water or person-to-person contact.
- Non-infectious diarrhea (caused by medications, dietary factors, or conditions) isn't contagious.
Risk Factors - Infectious Diarrhea
- Poor sanitation and hygiene.
- Contaminated food and water.
- Young children are more susceptible to severe cases.
Constipation
- Characterized by infrequent or difficult bowel movements, hard stools, and straining during bowel movements.
- Primary (functional) constipation involves normal stool passage rate, but defecation difficulty.
- This can be due to slow transit (reduced colonic motility), Irritable Bowel Syndrome (IBS) type C, or pelvic floor dysfunction.
- Secondary constipation is caused by conditions like dietary factors, medications (opioids, anticholinergics, iron supplements, etc) neurological disorders (multiple sclerosis, spinal cord injury), or structural issues (rectal issues, fissures, prolapses).
Pathophysiology of Constipation
- Slow transit constipation involves slow passage of stool through the colon, leading to excessive water absorption and hard, dry stools.
- Opioid-induced constipation involves the activation of opioid receptors in the gut, which reduces peristalsis and increases water absorption, leading to dry, hard stools.
Disease Transmission (Constipation)
- Constipation is not an infectious disease, so it's not transmissible.
- However, certain medications or lifestyle factors can trigger it.
Risk Factors - Constipation
- Low-fiber diet.
- Dehydration
- Lack of exercise
- Certain medications (e.g., opioids, iron supplements).
- Chronic laxative use
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Description
Explore the complexities of diarrhea, including osmotic and secretory types. Understand the causes, symptoms, and mechanisms behind increased stool frequency and fluid content. This quiz also covers disease transmission through infectious diarrhea.