Gastroesophageal Reflux Disease (GERD) Quiz

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Questions and Answers

What condition is indicated by the kidney secreting excess bicarbonate?

  • Hyponatraemia
  • Hypokalemia
  • Dehydration
  • Alkalosis (correct)

Which of the following symptoms is commonly associated with severe cases in this condition?

  • Confusion (correct)
  • Nausea and vomiting
  • Persistent cough
  • Severe headache

What investigation is used to show a 'soup dish appearance' indicating significant gastric dilation?

  • CT scan
  • Barium meal (correct)
  • MRI
  • Ultrasound

In response to hypokalemia, which electrolyte exchange occurs to maintain balance?

<p>Hydrogen exchanged with potassium (A)</p> Signup and view all the answers

What is the recommended intervention in all cases of this condition?

<p>Surgery or intervention (D)</p> Signup and view all the answers

What condition is characterized by the replacement of normal squamous epithelium with metaplastic columnar mucosa?

<p>Barrett’s esophagus (B)</p> Signup and view all the answers

Which complication of GERD is more likely to occur due to long-term reflux episodes?

<p>Barrett’s esophagus (B)</p> Signup and view all the answers

What is the prognosis for patients with Barrett’s esophagus concerning the risk of developing adenocarcinoma?

<p>40 times higher than normal individuals (A)</p> Signup and view all the answers

Which symptom is associated with acute mucosal inflammation and typically seen in erosive esophagitis?

<p>Post prandial symptoms (C)</p> Signup and view all the answers

What is the most common cause of strictures in the esophagus related to GERD?

<p>Peptic stricture due to fibrosis (D)</p> Signup and view all the answers

What is a common symptom indicating advanced disease in a patient?

<p>Inability to swallow saliva (B)</p> Signup and view all the answers

Which lymph nodes are involved in lymphatic spread?

<p>Cervical and abdominal celiac (D)</p> Signup and view all the answers

What complication might result from recurrent laryngeal nerve infiltration?

<p>Hoarseness of voice (C)</p> Signup and view all the answers

What investigation is most sensitive for determining tumor depth?

<p>Endoscopic ultrasound (EUS) (A)</p> Signup and view all the answers

What is a clinical sign often observed in patients with advanced carcinoma?

<p>Malnutrition and cachexia (C)</p> Signup and view all the answers

What procedure should be urgently performed in a middle-aged patient with dysphagia or odynophagia?

<p>EsophagoGastroscopy (EGD) + biopsy (D)</p> Signup and view all the answers

Which statement about the prognosis of advanced disease is correct?

<p>70% of patients die within a year (C)</p> Signup and view all the answers

What is an indication for staging investigations?

<p>To assess local invasion and metastases (B)</p> Signup and view all the answers

What is the most common timeframe for ulcers to heal with proper treatment?

<p>8–12 weeks (C)</p> Signup and view all the answers

Which substances should be eliminated to aid in the treatment of duodenal ulcers?

<p>Ethanol, tobacco, and NSAIDs (D)</p> Signup and view all the answers

Which component is NOT part of the triple therapy for eradication of H.pylori?

<p>Bismuth compounds (C)</p> Signup and view all the answers

What is considered a main disadvantage of medical treatment for duodenal ulcers?

<p>High rate of recurrence (D)</p> Signup and view all the answers

Which is an indication for surgical treatment of gastric ulcers?

<p>Intractability with no healing after 3 months (A)</p> Signup and view all the answers

Which of the following represents a strategy to prevent ulcer relapse?

<p>Interval therapy or maintenance therapy (C)</p> Signup and view all the answers

What is one of the main surgical options for a patient with chronic duodenal ulcers?

<p>Surgery for perforation (A)</p> Signup and view all the answers

What is a key component of quadruple therapy for H.pylori eradication?

<p>Bismuth compounds (A)</p> Signup and view all the answers

Which diagnostic method is considered the gold standard for diagnosing GERD and NERD?

<p>24 Hours esophageal pH studies (D)</p> Signup and view all the answers

What must be excluded before diagnosing GERD via upper endoscopy?

<p>Hiatal hernia (A), Esophageal cancer (C), Eosinophilic esophagitis (D)</p> Signup and view all the answers

Which of the following is a reason for providing palliative treatment?

<p>Systemic advanced disease with metastases (C)</p> Signup and view all the answers

What indicates a low pH reading in 24-hour pH studies for diagnosing GERD?

<p>Low pH &lt; 4 in episodes &gt; one hour (B)</p> Signup and view all the answers

Which diagnostic method has no role in diagnosing GERD?

<p>Barium swallow (B)</p> Signup and view all the answers

What surgical approach is associated with performing a three-stage esophagectomy?

<p>Right thoracotomy (A)</p> Signup and view all the answers

What is the value of esophageal manometry in the context of GERD?

<p>To assess low LES pressure (A)</p> Signup and view all the answers

In which scenario would a one-field oesophago-gastric resection be indicated?

<p>Very low tumors (Siewert type I) (A)</p> Signup and view all the answers

What is a component of the neoadjuvant therapy plus curative approach?

<p>Esophagectomy surgery (C)</p> Signup and view all the answers

What is a potential negative result of upper endoscopy when diagnosing NERD?

<p>20-40% negative results (C)</p> Signup and view all the answers

Why is impedance pH metry included in the diagnostic approach for GERD?

<p>To differentiate between acidic and alkaline reflux (C)</p> Signup and view all the answers

Which incision is used to mobilize the cervical esophagus in the treatment of cervical esophageal cancer?

<p>Left cervical incision (A)</p> Signup and view all the answers

What does the presence of alarm symptoms indicate in a patient with chronic GERD?

<p>Need for upper endoscopy with biopsy (B)</p> Signup and view all the answers

What technique is commonly used for the best palliation in palliative treatment?

<p>Endoscopic Stenting with self-expandable metallic stent (D)</p> Signup and view all the answers

Which of the following complications would most likely require bad general condition for a surgical intervention?

<p>Severe malnutrition (C)</p> Signup and view all the answers

What type of esophagectomy is indicated for lesions below the carina?

<p>Two-stage esophagectomy (D)</p> Signup and view all the answers

Flashcards

Erosive Esophagitis

Erosive esophagitis is an inflammation of the lining of the esophagus caused by GERD. It occurs when stomach acid repeatedly irritates the esophageal lining, leading to damage and ulceration.

Esophageal Stricture

A narrowing of the esophagus caused by scar tissue formation due to chronic acid reflux. It makes it difficult to swallow.

Barrett's Esophagus (BE)

Barrett's esophagus (BE) is a condition where the normal lining of the lower esophagus is replaced by a different type of lining similar to the stomach or intestines. It's a precancerous condition, meaning it can increase the risk of esophageal cancer over time.

Lower Esophageal Sphincter (LES)

A lower esophageal sphincter (LES) is a ring of muscle that helps to prevent stomach acid from flowing back up into the esophagus.

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Common GERD Symptoms

The most common symptoms of GERD are heartburn, acid reflux, and regurgitation. These are a result of stomach acid flowing back up into the esophagus.

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Dysphagia

Difficulty swallowing, often an early sign of esophageal cancer.

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Odynophagia

Painful swallowing, often associated with esophageal cancer.

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Esophagogastroduodenoscopy (EGD)

A procedure that allows visualization of the esophagus, stomach, and duodenum using a flexible endoscope with a camera.

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Endoscopic Ultrasound (EUS)

A type of ultrasound imaging specifically used to examine the layers of the esophagus and surrounding structures.

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Tracheoesophageal Fistula

A common complication of esophageal cancer, characterized by a weak cough and potential for aspiration.

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Virchow's Lymph Node

A type of lymph node located in the left supraclavicular fossa, often enlarged in advanced esophageal cancer. A bad sign.

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CT Scan of Chest and Abdomen

A diagnostic procedure used to stage a cancer by imaging the chest and abdomen to assess local spread, lymph nodes, and distant metastases.

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Patient Fitness Assessment

A group of tests assessing the patient's overall health and fitness for potential surgery. Includes cardiovascular, respiratory, and functional assessments.

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Upper Endoscopy with Biopsy

An invasive procedure used to visualize the esophagus and take biopsies. It helps diagnose erosive esophagitis, but not non-erosive reflux disease (NERD).

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24-hour Esophageal pH Studies

A gold standard test for diagnosing both GERD and NERD. It measures the pH of the esophagus over a 24-hour period.

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Diagnosing GERD with pH Studies

A diagnosis of GERD is made when the pH is below 4 for more than one hour during the 24-hour monitoring period, and acid episodes coincide with pain.

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24-hour pH Studies for NERD & Atypical Symptoms

Used primarily to diagnose NERD, atypical symptoms, and GERD patients who don't respond to medical treatment.

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Impedance pH Metry

A modified pH study that measures both pH and impedance. It helps identify non-acidic reflux.

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Esophageal Manometry

A procedure that assesses the strength of the lower esophageal sphincter (LES) and the function of esophageal muscles. It helps choose the right type of surgery for GERD.

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Barium Swallow (Trendelenburg position)

A test that involves swallowing barium while tilted backwards. It helps identify structural problems in the esophagus.

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Barium Swallow for GERD Diagnosis

This test has no proven value in diagnosing GERD and is not typically recommended for this purpose.

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Dilated Stomach

A condition where the stomach is significantly enlarged, often with a 'soup dish' appearance on barium meal imaging. It can lead to a variety of symptoms like fullness, nausea, and loss of appetite. The enlarged stomach can be so large that it can be seen below the iliac crest. There is a deformed pylorus.

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Succusion Splash

A physical finding where a sloshing sound is heard when the abdomen is shaken. It indicates the presence of air and fluid within the stomach.

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Visible Peristaltic Waves

Peristaltic waves are visible and move from left to right across the abdomen.

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Hypokalemia

The body loses potassium due to increased excretion in the urine. This occurs because the kidneys are trying to correct hypokalemia (low potassium) by exchanging potassium for hydrogen ions, which leads to paradoxical aciduria.

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Alkalosis

The body's pH becomes too alkaline, often due to prolonged vomiting and loss of stomach acid. It can lead to a number of complications, including muscle cramps, tetany, and confusion. It is treated by addressing the underlying cause of the alkalosis.

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Curative Esophagectomy

Surgery aimed at completely removing the cancer, often used for tumors located below the carina (lower two-thirds of the esophagus).

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Neoadjuvant Therapy

Surgery performed before any other treatment, often used to shrink the tumor before more aggressive treatment.

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Adjuvant Therapy

Treatment given after initial surgery, often used to kill any remaining cancer cells.

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Three-Stage Esophagectomy (McKeown Operation)

A surgical procedure that involves removing sections of the cervical, thoracic, and abdominal esophagus, and then attaching the stomach to the remaining esophagus. It's used when the tumor is located below the carina.

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Two-Stage Esophagectomy (Ivor-Lewis Operation)

A two-stage procedure used for tumors below the carina, involving removing the thoracic esophagus and connecting the stomach to the remaining esophagus.

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One-Field Oesophago-Gastric Resection

A single procedure involving removing the esophagus and stomach, and attaching the stomach to the remaining esophagus. Used for very low tumors (Siewert Type I).

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Palliative Treatment

Treatment aimed at relieving symptoms and improving quality of life, often used in advanced or difficult cases.

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Endoscopic Stenting

A metallic stent inserted into the esophagus to alleviate swallowing difficulties, often used in palliative treatment.

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Chronic Duodenal Ulcer Treatment

A medical treatment approach for chronic duodenal ulcers that aims to eliminate irritants and eradicate H. pylori.

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Histamine (H2) Blockers

Medications that decrease stomach acid production.

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Sucralfate

A medication that protects the stomach lining from acid damage.

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Triple Therapy (H. pylori Eradication)

Eradication of H. pylori bacteria, usually with a combination of antibiotics and a proton pump inhibitor (PPI).

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Proton Pump Inhibitor (PPI)

A type of medication that strongly inhibits stomach acid production.

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Intractability (Chronic Gastric Ulcer)

When a chronic gastric ulcer fails to heal after appropriate medical treatment, or it recurs within a year.

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Indications for Surgery (Chronic Gastric Ulcer)

When a chronic gastric ulcer doesn't respond to medication or develops complications like bleeding, perforation, or blockage in the stomach outlet.

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Study Notes

Upper GIT Surgery

  • Esophagus - page 1
  • Bariatric surgery - page 1
  • Stomach - page 1
  • Minimally invasive surgeries - page 1
  • Hepatobiliary surgery - page 1
  • Gall bladder - page 1
  • Pancreas - page 1
  • Liver - page 1
  • Spleen - page 1

Esophagus

  • Gastroesophageal reflux disease - page 2
  • Hiatus Hernia - page 2
  • Esophageal Webs - page 2
  • Achalasia of the Esophagus - page 2
  • Esophageal Diverticula - page 2
  • Esophageal Tumors - page 2
  • Esophageal Perforation - page 2

Upper GIT Surgery

  • Upper esophageal sphincter (UES) - page 3
  • Lower esophageal sphincter (LES) - page 3
  • Muscularis propria of upper 1/3 - page 3
  • Peristalsis - page 3
  • Primary - page 3
  • Secondary - page 3
  • Tertiary - page 3
  • Dysphagia - page 3
  • Most of esophageal lesions - page 3
  • Benign Lesions - page 3
  • Diseases of the Esophagus - page 3
  • SCC - page 3
  • Malignant lesions - page 3

GERD (Gastroesophageal reflux Disease)

  • Factors preventing or causing GERD - page 4
  • Lower esophageal sphincter (LES) - page 4
  • Components of LES - page 4
  • Esophageal clearance - page 4
  • Delayed gastric emptying - page 4
  • Age, All ages, but M/C > 40year -Sex: ♂ = - GERD presentations (3 classes of symptoms) - page 4
  • Typical symptoms - page 4
  • Alarming S/S - page 4
  • Atypical symptoms - page 4
  • Complications of GERD - page 4

UPPER GIT SURGERY

  • Investigations- page 5
  • Diagnosis GERD - page 5
  • Diagnosis of GERD - page 5
  • Diagnosis of NERD/Atypical symptoms - page 5

UPPER GIT SURGERY

  • Diagnostic evaluation - page 6
  • Conservative/Medical ttt - page 6
  • Goals of therapy - page 6
  • Preventive complications - page 6
  • Therapy - page 6
  • Surgery - page 6
  • Treatment - page 6
  • Endoscopic ttt - page 6
  • Ttt of complications - page 6

H2-Receptor Antagonists (H2B) - page 7

  • Ranitidine 150-300 mg tab - page 7
  • Famotidine 20-40 mg tab - page 7
  • Proton pump inhibitor (PPI) - page 7
  • Pantoprazole - page 7
  • Esomeprazole - page 7
  • Ccc - page 7

Laparoscopic fundoplication - page 7

  • Types fundoplication - page 7
  • Complications- page 7

Hiatus Hernia - page 8

  • Type I (80%) - page 8
  • Sliding hiatal hernia - page 8
  • Symptomatic - page 8
  • Type II - page 8
  • Paraesophageal hiatus hernia - page 8
  • GEJ in abdomen - page 8
  • Complications: - page 8
  • Treatment: - page 8
  • Esophageal Webs - page 8
  • Circumferential mucosal folds - page 8
  • Etiology: - page 8
  • Esophageal Web Upper esophagus - page 8

Achalasia of the Esophagus - page 9

  • Pathophysiology & Etiology - page 9
  • Chest X-ray - page 9
  • Upper GIT Endoscopy - page 9
  • LES pressure - page 9
  • Tertiary contractions - page 9
  • Lost peristalsis - page 9
  • Fundic air bubble - page 9
  • Bird or Parrot Beak: - page 9
  • Sigmoid Esophagus - page 9
  • Differential diagnosis - page 9

Treatment of achalasia - page 10

  • Pharmacotherapy (Botulinum injection) - page 10
  • Method - page 10
  • Complications - page 10
  • Pneumatic balloon dilatation - page 10
  • Method- page 10
  • Disadvantages- page 10
  • Indications - page 10
  • Surgery (Open - laparscopic) - page 10
  • Open - page 10
  • Laparoscopic - page 10

Esophageal Diverticula - page 11

  • Site - page 11
  • Etiology - page 11
  • Clinical Picture - page 11
  • Complications - page 11
  • Treatment - page 11
  • Diagnosis - page 11

Esophageal Tumors - page 12

  • Benign Esophageal Neoplasms - page 12
  • Malignant Esophageal Neoplasms - page 12
  • PDFs - page 12
  • Radiology - page12
  • Mac -page 12
  • Spread -page12

Investigations- page 13

  • For primary lesion - page 13
  • For staging & to assess operability - page 13
  • Assessment Patient Fitness - page 13

Palliative treatment - page 14

  • Indications - page 14
  • Palliative measures - page 14
  • Neoadjuvant therapy - page 14

Complications of Esophagectomy - page 15

  • Early Postoperative - page 15
  • Late Postoperative - page 15
  • Siewert classification - page 15
  • Causes - page 15
  • Investigations - page 15
  • Lines of treatment - page 15

Grades of Obesity - page 16

  • Grades of Obesity - page 16
  • Co-morbidities of obesity - page 16

Medical complications (co-morbidities of obesity) - page 17

  • Type II DM - page 17
  • Hypertension - page 17
  • Hypertriglyceridemia & hypercholesterolemia - page 17
  • CVS - page 17
  • Respirtory - page 17
  • GIT - page 17
  • Other complications - page 17
  • Other grading system - page 17

Types and Indications of Bariatric Surgery - page 18

  • Restrictive Surgery - page 18
  • Laparoscopic adjustable gastric banding (LAGB) - page 18
  • Gastric placation - page 18
  • Bulk eaters - page 18
  • Indications - page 18
  • Procedure - page 18
  • Advantages - page 18
  • Disadvantages & Complications - page 18
  • Vertical band gastroplasty (VBG) - page 18
  • Combined restrictive and malabsorptive - page 18

Technique: Sleeve Gastrectomy - page 19

  • Advantages - page 19
  • Disadvantages & complications - page 19
  • Late complications - page 19

Roux-en-Y gastric bypass (RYGB) - page 20

  • One Anastomosis (Mini) Gastric bypass (OAGB) - page 20
  • Technique - page 20
  • Ccc & diadv- page 20
  • Outcome - page 20

Malabsorptive Surgery - page 21

  • Bilio-pancreatic Diversion (BPD) - page 21
  • BPD with duodenal switch DS - page 21

Acute Gastric Dilatation - page 23

  • Acute Peptic Ulcer - page 23
  • Chronic Duodenal ulcer - page 24
  • Chronic gastric ulcer - page 24
  • Bleeding peptic ulcer - page 24
  • Perforated peptic ulcer - page 24
  • Gastric outlet obstruction (GOO)- page 24

Chronic Duodenal Ulcer - page 25

  • Age, Sex - page 25
  • Etiology - page 25
  • Patho - page 25
  • Number - page 25
  • Site -page 25

Chronic Gastric Ulcers - page 25

  • Incidence - page 25
  • Etiology - page 25
  • Patho - page 25
  • C/O(Chronic Duodenal Ulcer) -page 26
  • O/E -page 26
  • Inv - page 26
  • Diagnosis - page 26
  • TTT- page 26

Bleeding peptic ulcer - page 30

  • Inv - page 30
  • Ttt - page 30

Perforated peptic ulcer - page 30

  • Causes - page 30
  • Investigations - page 30
  • Lines of treatment - page 30

Pyloric Stenosis - page 33

  • C/O - page 33
  • Clinical Picture - page 33
  • Investigations - page 33
  • Treatment - page 33

Tumors of the Stomach - page 34

  • Benign Esophageal Neoplasms- page 34
  • Malignant Esophageal Neoplasms- page 34
  • PDFs - page 34
  • Pathology - page 34
  • Spread - page 34
  • Prognosis - page 34

Carcinoma of the stomach - page 34

  • Benign Esophageal Neoplasms- page 34
  • Malignant Esophageal Neoplasms- page 34
  • PDFs - page 34
  • Epidemiology - page 34
  • Pathology -page 34

Pathology of Tumors of the Stomach - page 35

  • Gross pathology - page 35
  • Microscopic picture - page 35
  • Intestinal Type - page 35

Investigations - page 36

  • For primary lesion - page 36
  • For staging & to assess operability - page 36
  • Gastric carcinoma - page 36

Tumours of the Body & Fundus - page 37

  • Principles of radical surgery - page 37
  • Treatment - page 37

Carcinoma of the Body and Tail of the Pancreas - page 38

  • Epidemiology - page 38
  • Etiology - page 38
  • Pathology - page 38
  • Clinical Picture - page 38
  • Malignant Obstructive Jaundice- page 38

Pathology of Pancreatic Tumors - page 39

  • Gross pathology - page 39
  • Microscopic picture - page 39
  • Intestinal Type - page 39
  • Diffuse Type - page 39
  • Presentation usually precedes metastasis - page 39
  • Investigations - Page 39
  • Routine laboratory of O.J. - Page 39
  • Abdominal U.S - Page 39
  • Other investigations - Page 39

Pancreatic Ascites - page 39

  • Def - page 39
  • Etiology - page 39
  • Pathology - page 39
  • Clinical picture- page 39
  • Investigations -Page 39
  • Treatment - page 39

Chronic Duodenal Ileus - page 39

  • Definition - page 39
  • Etiology - page 39
  • C/P - page 39
  • Investigations - page 39
  • Treatment - page 39

Haematemesis - page 40

  • Causes - page 40
  • Investigations - page 40
  • Treatment - page 40

Miscellaneous causes of haematemesis - page 41

  • Mallory Weiss tear - page 41
  • Dieulafoy Gastric Lesion - page 41
  • Aortic enteric fistula- page 41

Postgastrectomy Syndromes - page 42

  • Reflux Alkaline - page 42
  • Afferent Loop Syndrome - page 42
  • Dumping Syndrome - page 42
  • Treatments of dumping syndrome - page 42
  • Nutritional disturbances - page 42

Minimal Invasive Surgery (MIS) - page 43

  • Small wounds - page 43
  • Minimizing the surgical trauma - page 43
  • Minimizing blood loss - page 43
  • All these factors- page 43

Preparation for laparoscopic or robotic surgery - page 44

  • History - page 44
  • Examination - page 44
  • Pre-medication & Prophylaxis - page 44
  • Urinary catheters & nasogastric tubes - page 44
  • Informed consent - page 44

Surgical Principles of MIS - page 45

  • Meticulous care in the creation of a pneumoperitoneum - page 45

Laparoscopic Instruments- page 46

  • Disadvantages & Complications- page 46
  • Complications: - page 46
  • Contraindications- page 46

Laparoscopic staging for abdominal malignancies - page 47

  • Aim - page 47
  • Indications page 47
  • Contraindications- page 47
  • Early disease- page 47
  • Local disease- page 47
  • Advanced disease- page 47
  • Metastatic disease- page 47

Tumours of the Body & Fundus - page 47

Bile Duct Injury- page 58

  • Etiology - page 58
  • Presentation (oj dt traumatic stricture)- page 58
  • Investigations - page 58
  • Treatment - page 58

Primary Sclerosing Cholangitis (PSC) - page 59

  • Etiopathophysiology - page 59
  • Epidemiology - page 59
  • Diagnosis - page 59

Carcinoma of the Gallbladder - page 59

  • Etiology - page 59
  • Pathology - page 59
  • Clinical Picture - page 59
  • Treatment - page 59

Calcular Obstructive Jaundice - page 54

  • Clinical picture - page 54
  • Sequelae & Complications - page 54

Lab of Chronic Calcular Cholecystitis - page 52

  • Investigations - page 52

Chronic Calcular Cholecystitis - page 50

  • Acute Calcular Cholecystitis - page 50
  • Complications of Acute - page 51
  • Etiology- page 51
  • Calcular Obstructive Jaundice - page 53
  • Clinical C/O - page 53
  • Common bile duct stones - page 53
  • Sequelae & Complications - page 54
  • Differential diagnosis of calcular obstructive jaundice - page 54

Pyogenic Liver Abscess - page 80

  • Etiology - page 80
  • Presentation - page 80
  • Inv- page 80
  • Ttt -page 80
  • CT/US- guided percutaneous aspiration - page 81
  • Medical treatment - page 81
  • Complications - page 81

Benign Liver Tumors - page 82

  • Liver Hemangioma - page 82
  • Focal nodular hyperplasia - page 82
  • Hepatocellular adenoma (HCA) - page 82

Hepatic focal lesions - page 77

  • Cystic - page 77
  • solid - page 77
  • Malignant - page 77
  • Secondary (metastatic) - page 77
  • Liver cysts - page 77

Hepatocellular Carcinoma (HCC) - page 84

Secondary Liver Tumors - page 88

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