Gastrin, HCl, and Mucous in Stomach Physiology
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Questions and Answers

Which factor is responsible for protecting the mucosa by secreting mucus and bicarbonate ion?

  • Gastrin
  • Parietal cells
  • Histamine
  • Prostaglandin (correct)

    • What is a common environmental factor that plays a role in the formation of peptic ulcers?

  • Alcohol consumption
  • Antioxidant intake
  • NSAIDs (correct)
  • Regular exercise

    • What is the mechanism of action of Histamine H2 receptor antagonists in treating peptic ulcers?

  • Reducing gastric acid secretion (correct)
  • Increasing acid production
  • Promoting mucosal blood flow
  • Decreasing prostaglandin levels

    • Which of the following is NOT a line of treatment for peptic ulcers?

    <p>Bronchodilators</p> Signup and view all the answers

    Which component is directly responsible for neutralizing acidity in the stomach for peptic ulcer treatment?

    <p>Antacids</p> Signup and view all the answers

    Which infection requires antibiotic treatment for eradication in patients with peptic ulcers?

    <p>Helicobacter pylori</p> Signup and view all the answers

    Which of the following statements about proton pump inhibitors (PPIs) is correct?

    <p>PPIs form covalent bonds with the H⁺/K⁺ ATPase enzyme in the parietal cell canaliculi.</p> Signup and view all the answers

    Which of the following is the primary function of H⁺/K⁺ ATPase in the parietal cells?

    <p>Acidifying the stomach contents.</p> Signup and view all the answers

    What is the primary cause of peptic ulcers?

    <p>Helicobacter pylori infection.</p> Signup and view all the answers

    Which of the following is the recommended first-line treatment for Helicobacter pylori eradication?

    <p>Clarithromycin-based triple therapy.</p> Signup and view all the answers

    Which of the following statements about the pharmacokinetics of proton pump inhibitors (PPIs) is correct?

    <p>PPIs are well-tolerated and have few side effects.</p> Signup and view all the answers

    Which of the following statements about the mechanism of action of proton pump inhibitors (PPIs) is incorrect?

    <p>PPIs inhibit the exchange of H⁺ and K⁺ ions across the basolateral membrane of parietal cells.</p> Signup and view all the answers

    Which of the following is the primary cause of peptic ulcers?

    <p>Infection with Helicobacter pylori bacteria</p> Signup and view all the answers

    Which of the following is NOT a function of parietal cells in the stomach?

    <p>Secretion of bicarbonate ions (HCO3-)</p> Signup and view all the answers

    Which of the following drugs is classified as an H2-receptor antagonist used for the treatment of peptic ulcers?

    <p>Ranitidine</p> Signup and view all the answers

    In the eradication of Helicobacter pylori infection, which of the following drug combinations is commonly used?

    <p>Proton pump inhibitor + Clarithromycin + Amoxicillin</p> Signup and view all the answers

    Which of the following statements about the mechanism of gastric acid secretion is correct?

    <p>Gastrin increases in response to a reduction in hydrochloric acid (HCl) levels</p> Signup and view all the answers

    What is the mechanism of action of H2-receptor antagonists in the treatment of peptic ulcers?

    <p>Inhibition of gastric acid secretion by blocking histamine H2 receptors</p> Signup and view all the answers

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