Gastric Motility and Secretion Hormones Summary

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10 Questions

What is the enzyme responsible for breaking down carbohydrates in the mouth?

Salivary amylase

Which phase of swallowing is considered voluntary?

Buccal Phase

Which neurotransmitter stimulates the secretion of thin, enzyme-rich saliva from the salivary glands?

Acetylcholine

Where does absorption primarily occur within the digestive system?

Small intestine

Which of the following is NOT an accessory organ of the digestive system?

Stomach

What type of contractions are responsible for mixing food in the digestive tract?

Segmentation

Which phase of swallowing is mediated by signals to the swallowing center in the medulla?

Pharyngeal Phase

Which enzyme in the mouth is responsible for breaking down triglycerides into fatty acids and monoglycerides?

Lingual lipase

Which type of saliva is stimulated by the sympathetic nervous system?

Thick, mucus-rich saliva.

What is the primary function of lingual lipase in digestion?

Breaking down triglycerides.

Study Notes

Digestion Overview

  • Digestion involves 4 basic processes: digestion, absorption, motility, and secretion
  • Involves the digestive tract (mouth to anus) and accessory organs (e.g., teeth, tongue, salivary glands, liver, gallbladder, pancreas)

Gastric Motility and Secretion

  • Slowed down by CCK (released due to presence of fatty acids and amino acids) and enterogastric reflex (triggered by amino acids/peptides, acid, duodenal stretch, and hypertonicity)
  • Gastric secretion is regulated by:
    • Gastrin: stimulates acid and gastric enzyme secretion
    • Secretin: released due to acid, stimulates alkaline fluid secretion and reduces gastric secretion
    • CCK: released due to amino acids and fatty acids, stimulates pancreatic enzyme secretion, gallbladder contraction, and reduces gastric motility and secretion

Hormone Summary

  • Gastrin: stimulates acid and gastric enzyme secretion
  • Secretin: stimulates alkaline fluid secretion and reduces gastric secretion
  • CCK: stimulates pancreatic enzyme secretion, gallbladder contraction, and reduces gastric motility and secretion

Large Intestine Motility

  • Haustral contractions: slow and weak, allowing mixing and absorption of salts and water
  • Mass movements: powerful waves of contractions triggered by food in the stomach, moving fecal mass to the rectum
  • Rectal (defecation) reflex: stimulated by feces in the rectum, involving the sacral segment of the spinal cord and smooth muscle contractions

Micelle Formation

  • Micelle: formed by bile salts and phospholipids, with a hydrophobic interior and hydrophilic exterior
  • Emulsification of lipid globules, lipase, and fatty acids + monoglycerides
  • Micelle diffuse into enterocyte, where fatty acids + monoglycerides are absorbed

Gastric Motility/Secretion Regulatory Phases

  • Cephalic phase: prepares stomach for food, triggered by thought, sight, smell, and taste of food, stimulating enzymes and acid secretion
  • Gastric phase: food buffers pH, which slowly decreases, reaching 3 when the stomach is nearly empty, shutting down acid and enzyme secretion
  • Intestinal phase: regulates rate of chyme entry into duodenum, controlling acid neutralization, tonicity, and digestion and absorption in the small intestine

This quiz covers the regulation of gastric motility and secretion through hormones like CCK, Secretin, and Gastrin. Understand how factors like the presence of food, amino acids, peptides, and duodenal stretch affect the digestive processes in the stomach and duodenum.

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