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Questions and Answers
What is the relationship between the partial pressure difference of O2 and CO2?
What is the relationship between the partial pressure difference of O2 and CO2?
- The partial pressure difference of O2 is equal to that of CO2.
- The partial pressure difference of O2 is ten times greater than CO2. (correct)
- The partial pressure difference of CO2 is twice that of O2.
- The partial pressure difference of CO2 is ten times greater than O2.
How does the solubility of CO2 compare to that of O2?
How does the solubility of CO2 compare to that of O2?
- CO2 is 10 times more soluble than O2.
- CO2 is 20 times more soluble than O2. (correct)
- CO2 is equally soluble as O2.
- CO2 is less soluble than O2.
What can be inferred from the pressure and solubility differences?
What can be inferred from the pressure and solubility differences?
- A higher solubility indicates a lower partial pressure difference. (correct)
- Higher partial pressure leads to higher solubility.
- The rate of transfer is solely dependent on the solubility of the gas.
- The pressure difference of a gas has no effect on its solubility.
If the difference stated is 6, what does this imply about the gases being discussed?
If the difference stated is 6, what does this imply about the gases being discussed?
Why is understanding the solubility relationship between CO2 and O2 important?
Why is understanding the solubility relationship between CO2 and O2 important?
What happens to the concentration of gas in the alveoli after breathing?
What happens to the concentration of gas in the alveoli after breathing?
Which statement best describes the condition of excess gas in the alveoli?
Which statement best describes the condition of excess gas in the alveoli?
In which area is the maximum concentration of gas found?
In which area is the maximum concentration of gas found?
What is a primary factor affecting gas concentration in the alveoli?
What is a primary factor affecting gas concentration in the alveoli?
Which option correctly states the role of the alveoli in gas exchange?
Which option correctly states the role of the alveoli in gas exchange?
What is the primary function of pulmonary surfactant in the alveoli?
What is the primary function of pulmonary surfactant in the alveoli?
Which type of cell is primarily responsible for the gas exchange process in the alveoli?
Which type of cell is primarily responsible for the gas exchange process in the alveoli?
What is the approximate thickness of the red blood cell in the middle?
What is the approximate thickness of the red blood cell in the middle?
Which component is NOT involved in the alveolar process of oxygen exchange?
Which component is NOT involved in the alveolar process of oxygen exchange?
What structure provides the primary site for the transfer of oxygen into the blood?
What structure provides the primary site for the transfer of oxygen into the blood?
What is the standard oxygen consumption rate mentioned?
What is the standard oxygen consumption rate mentioned?
What is the approximate ventilatory rate indicated?
What is the approximate ventilatory rate indicated?
What is the desired alveolar partial pressure of O2 (PO2) maintained?
What is the desired alveolar partial pressure of O2 (PO2) maintained?
Which of the following best describes the relationship between oxygen consumption and ventilatory rate?
Which of the following best describes the relationship between oxygen consumption and ventilatory rate?
Which of these values is not mentioned in the context provided?
Which of these values is not mentioned in the context provided?
What is transported by the pulmonary artery?
What is transported by the pulmonary artery?
What is the primary function of the alveolus?
What is the primary function of the alveolus?
Which structure directly connects the pulmonary arteries to the alveolar sacs?
Which structure directly connects the pulmonary arteries to the alveolar sacs?
What role do the Pores of Kohn serve in the lungs?
What role do the Pores of Kohn serve in the lungs?
What is a key component of the alveolar sac structure?
What is a key component of the alveolar sac structure?
What is the partial pressure of oxygen (PO₂) in the alveoli?
What is the partial pressure of oxygen (PO₂) in the alveoli?
How is the partial pressure of oxygen calculated from atmospheric conditions?
How is the partial pressure of oxygen calculated from atmospheric conditions?
What is the primary factor that drives the diffusion of oxygen from the alveoli into the blood?
What is the primary factor that drives the diffusion of oxygen from the alveoli into the blood?
What happens to PO₂ after oxygen exchange in the tissues?
What happens to PO₂ after oxygen exchange in the tissues?
What is the primary mechanism by which carbon dioxide diffuses from tissues to the blood?
What is the primary mechanism by which carbon dioxide diffuses from tissues to the blood?
What is the PCO₂ level in the tissues compared to arterial blood after gas exchange?
What is the PCO₂ level in the tissues compared to arterial blood after gas exchange?
What causes the decrease in PO₂ from the atmosphere to the alveoli?
What causes the decrease in PO₂ from the atmosphere to the alveoli?
Why is it important to maintain a gradient of partial pressure for O₂ in respiration?
Why is it important to maintain a gradient of partial pressure for O₂ in respiration?
What is the PCO₂ level in the atmosphere compared to that in the arterial blood?
What is the PCO₂ level in the atmosphere compared to that in the arterial blood?
What is the main role of oxygen after it enters the bloodstream?
What is the main role of oxygen after it enters the bloodstream?
Flashcards
Alveolar air
Alveolar air
Air present inside the alveoli.
Gas concentration in alveoli
Gas concentration in alveoli
The concentration of a gas inside an alveolus is highest at the top left corner of the alveolus.
Gas concentration change after breathing
Gas concentration change after breathing
The concentration of a gas inside an alveolus decreases after breathing.
Excess gas in alveoli
Excess gas in alveoli
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Dynamic nature of gas in alveoli
Dynamic nature of gas in alveoli
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Oxygen Consumption
Oxygen Consumption
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Ventilatory Rate
Ventilatory Rate
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Alveolar Partial Pressure of Oxygen (PaO2)
Alveolar Partial Pressure of Oxygen (PaO2)
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Normal PaO2
Normal PaO2
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PaO2 Regulation
PaO2 Regulation
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Partial Pressure of Oxygen (PO2)
Partial Pressure of Oxygen (PO2)
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Atmospheric Partial Pressure of Oxygen (P atm O2)
Atmospheric Partial Pressure of Oxygen (P atm O2)
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Blood Partial Pressure of Oxygen (Pa O2)
Blood Partial Pressure of Oxygen (Pa O2)
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Partial Pressure Gradient
Partial Pressure Gradient
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Cellular Partial Pressure of Oxygen (P cell O2)
Cellular Partial Pressure of Oxygen (P cell O2)
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Oxygen Diffusion across Pulmonary Capillaries
Oxygen Diffusion across Pulmonary Capillaries
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Oxygen Diffusion across Systemic Capillaries
Oxygen Diffusion across Systemic Capillaries
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Carbon Dioxide Transport
Carbon Dioxide Transport
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Partial Pressure of Carbon Dioxide (PCO2)
Partial Pressure of Carbon Dioxide (PCO2)
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Partial Pressure Difference of O2
Partial Pressure Difference of O2
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Partial Pressure Difference of CO2
Partial Pressure Difference of CO2
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Rate of Gas Transfer
Rate of Gas Transfer
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Solubility of a Gas
Solubility of a Gas
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10 Times More Partial Pressure Difference of O2
10 Times More Partial Pressure Difference of O2
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Alveolus
Alveolus
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Respiratory bronchiole
Respiratory bronchiole
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Pulmonary capillaries
Pulmonary capillaries
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Ventilation
Ventilation
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Respiratory Membrane
Respiratory Membrane
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Type II Alveolar Cell
Type II Alveolar Cell
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Type I Alveolar Cell
Type I Alveolar Cell
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Alveolar Macrophage
Alveolar Macrophage
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Study Notes
Gas Exchange
- Gas exchange is a vital process in respiration, facilitating the transfer of oxygen and carbon dioxide across pulmonary and tissue capillaries. This process is driven by simple diffusion.
- Air is a mixture of gases; each gas's partial pressure depends on its concentration. For instance, nitrogen (N2) is 79% of atmospheric air, and its partial pressure is calculated by multiplying the overall atmospheric pressure (760 mmHg) by its percentage (0.79).
- Spirograms record the volume of air entering and leaving the lungs. This helps determine lung capacity.
- Four main lung volumes are: tidal volume (TV), inspiratory reserve volume (IRV), expiratory reserve volume (ERV), and residual volume (RV).
- Four main lung capacities are: inspiratory capacity (IC), functional residual capacity (FRC), vital capacity (VC), and total lung capacity (TLC).
- The exchange of gases is a passive process in the exhalation and an active process in inhalation.
- The partial pressure gradients drive gas exchange across the pulmonary and systemic capillaries.
Factors Affecting Gas Diffusion
- Thickness of the respiratory membrane: A thicker membrane slows down gas transfer; conditions like pulmonary fibrosis increase thickness.
- Surface area of the alveolar membrane: A larger surface area promotes faster gas transfer; exercise increases surface area and lung collapse decreases it.
- Diffusion constant: Carbon dioxide's diffusion constant is 20 times higher than oxygen's, influencing its faster transfer rate.
- Partial pressure difference of oxygen and carbon dioxide: A higher difference in partial pressure between the lungs and tissues promotes quicker gas transfer.
Normal Gas Values in Alveoli, Arterial and Mixed Venous Blood
Parameter | Alveoli | Arterial Blood | Mixed Venous Blood |
---|---|---|---|
PA O₂ (mmHg) | 104 | 100 | 40 |
PA CO₂ (mmHg) | 40 | 40 | 46 |
HCO₃⁻ (mEq/L) | 22-28 | 22-28 | |
pH | 7.45 | 7.35 | |
SaO₂ | 97% | 97% | 75% |
PvO₂ | 40 | ||
PvCO₂ | 46 |
- The values are approximate and can naturally vary.*
CO₂ Transport
- Carbon dioxide (CO₂) moves from venous blood to lungs by simple diffusion.
- Bicarbonate (HCO₃⁻) is crucial for CO₂ transport in the blood. It's a buffer, to maintain blood pH stability.
Oxygen Transport
- Hemoglobin, a protein in red blood cells, carries oxygen.
- The oxygen-hemoglobin dissociation curve shows how oxygen binding varies with different oxygen partial pressures in blood.
Definitions
- Alveolar gas: Gases (oxygen, carbon dioxide) found in the alveoli, the tiny air sacs in the lungs.
- Partial pressure: Pressure exerted by a single gas in a mixture of gases.
- Saturation: Percentage of hemoglobin molecules bound to oxygen.
- Concentration: Amount of a substance within a specific volume.
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