Functions of Ovaries
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Questions and Answers

Which tissue is involved in the synthesis of all three forms of estrogen (E1, E2, and E3)?

  • Placenta
  • Ovaries (correct)
  • Adipose Cells
  • Peripheral Tissues

Which enzyme complex is responsible for the aromatization of androgens in the synthesis of estrogens?

  • Dehydrogenase enzyme complex
  • Aromatase enzyme complex (correct)
  • Peroxidase enzyme complex
  • Reductase enzyme complex

From which androgen is Estradiol (E2) synthesized?

  • Dehydroepiandrosterone (DHEA)
  • Dihydrotestosterone (DHT)
  • Testosterone (correct)
  • Androstenedione

Which hormone is produced in significant amounts by the peripheral aromatization of androgens?

<p>Estradiol (B)</p> Signup and view all the answers

Which specific tissue is NOT mentioned as a site for peripheral estrogen synthesis?

<p>Kidneys (C)</p> Signup and view all the answers

Which hormone is responsible for the estrogen synthesis during pregnancy?

<p>Estriol (E3) (A)</p> Signup and view all the answers

Study Notes

Functions of Ovaries

  • Ovaries perform two main functions: producing female sex hormones and female germ cells (ova).
  • Female sex hormones synthesized by ovaries include estrogens and progesterone.

Synthesis of Ovarian Hormones

  • Estrogens are a family of hormones synthesized in various tissues, including ovaries, peripheral tissues, and placenta during pregnancy.
  • Three main types of estrogens are:
    • Estradiol (E2), the main estrogen, synthesized by ovaries and peripheral tissues.
    • Estrone (E1), synthesized by ovaries and peripheral tissues.
    • Estriol (E3), synthesized during pregnancy from the placenta and during metabolism of E2 and E1.
  • Peripheral tissues involved in estrogen synthesis include adipose cells, liver, brain, skin, and other tissues.
  • The pathway for ovarian estrogen synthesis (E2 and E1) is similar to testicular androgen synthesis, with additional aromatization reactions.
  • Estradiol is formed from the aromatization of testosterone.
  • Estrone results from the aromatization of androstenedione.
  • Peripheral aromatization of androgens by aromatase enzyme complex in peripheral tissues produces significant amounts of estrogens.

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Description

Learn about the two main functions of ovaries, including the production of female sex hormones and female germ cells, and the synthesis of estrogen hormones.

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