Functional roles and significance of connective tissues
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Questions and Answers

Which characteristic primarily dictates the functional role of each type of cartilage (hyaline, elastic, and fibrocartilage) within the body?

  • The varying proportions of collagen and elastic fibers within their extracellular matrix. (correct)
  • The reliance on blood vessels for nutrient supply and waste removal.
  • The structural organization of proteoglycans.
  • The presence or absence of chondrocytes within the extracellular matrix.

How does the unique composition of hyaline cartilage contribute to its function in frictionless joint movement, and which component plays a crucial role in maintaining its structural integrity under compression?

  • High elastin content ensures flexibility, while type I collagen resists compressive forces.
  • Mineralized matrix offers rigidity, and the lack of nerve endings prevents pain during high-impact activities.
  • The presence of blood vessels provides continuous nutrient supply, while chondrocytes directly bear compressive loads.
  • The glossy surface reduces friction, and the high fluid content, facilitated by hydrophilic proteoglycans, maintains integrity under compression. (correct)

In tendons, what is the functional significance of the parallel arrangement of type I collagen fibrils, and how does this arrangement influence the tissue's response to applied forces?

  • It facilitates nutrient diffusion throughout the tendon, supporting cellular metabolic activity.
  • It allows for multidirectional flexibility, accommodating a wide range of joint movements.
  • It provides high tensile strength along the axis of force transmission, enabling effective muscle-bone connection. (correct)
  • It enhances the tissue's ability to resist compressive forces, protecting underlying structures from damage.

How do ligaments differ structurally from tendons to fulfill their specific function in maintaining joint integrity, and what component contributes most significantly to this difference?

<p>Ligaments have a higher proportion of elastic fibers and a less ordered fibril arrangement compared to tendons. (C)</p> Signup and view all the answers

How does the study of kinematics enhance our understanding of human movement, and what distinguishes it from other approaches in biomechanics?

<p>It examines the spatial and temporal aspects of movement, such as displacement and velocity, independent of forces. (D)</p> Signup and view all the answers

How does pennation angle most significantly affect muscle force generation?

<p>By optimizing the alignment of muscle fibers to the axis of force transmission, affecting the effective force. (A)</p> Signup and view all the answers

What is the functional significance of arranging sarcomeres in series within a muscle fiber?

<p>Increasing the range of muscle contraction and overall muscle shortening velocity. (B)</p> Signup and view all the answers

In the context of connective tissue (CT), what roles do proteoglycans, fibronectin, chondronectin, and integrins play within the extracellular matrix (ECM)?

<p>Regulating cellular adhesion, transmitting mechanical signals, and modulating tissue hydration. (A)</p> Signup and view all the answers

What key determinant primarily dictates the passive tension characteristics of a muscle?

<p>The composition and organization of extracellular matrix components within the muscle, such as collagen and elastin. (A)</p> Signup and view all the answers

How does the physiological cross-sectional area (PCSA) of a muscle relate to its force-generating capacity?

<p>PCSA is directly proportional to force; a larger PCSA indicates a greater number of parallel sarcomeres, thus increasing overall force capacity. (A)</p> Signup and view all the answers

What is the primary role of collagen within the extracellular matrix of connective tissue?

<p>To resist tensile forces and provide structural support to the tissue. (C)</p> Signup and view all the answers

Considering the force-velocity relationship of skeletal muscle, what adaptation would most likely occur in a sprinter's muscles compared to a long-distance runner, assuming all other factors are equal?

<p>A shift towards a higher proportion of fast-twitch fibers to generate greater force at higher velocities. (D)</p> Signup and view all the answers

How do the parallel and series arrangements of sarcomeres in muscle fibers affect the length-tension relationship?

<p>Sarcomeres in parallel increase force production, while sarcomeres in series increase the range of muscle contraction. (B)</p> Signup and view all the answers

A material subjected to a torsional load experiences deformation primarily due to which type of stress?

<p>Shear stress, varying across the material's cross-section. (B)</p> Signup and view all the answers

Consider two materials, A and B, with material A having a steeper slope on its load-deformation curve compared to material B. What can be definitively concluded about these materials?

<p>Material A is stiffer than material B. (C)</p> Signup and view all the answers

For a given compressive load, trabecular bone exhibits a larger deformation compared to cortical bone. Which statement accurately describes the material properties that explain this difference?

<p>Trabecular bone has a lower stiffness and higher compliance than cortical bone. (B)</p> Signup and view all the answers

In a load-deformation curve, what does the area under the curve (AUC) represent, and how is it practically significant?

<p>The AUC represents stored energy and indicates the amount of energy a material can absorb before failure. (B)</p> Signup and view all the answers

A force of 50 N is applied to two different materials. Material A has a cross-sectional area of 2 $m^2$, while Material B has a cross-sectional area of 5 $m^2$. Determine the stress experienced by each material and select the correct conclusion.

<p>Material A: 25 Pa, Material B: 10 Pa; Material A experiences greater stress. (D)</p> Signup and view all the answers

A metal rod with an initial length of 2 meters is subjected to a tensile force, resulting in an elongation of 0.04 meters. What is the tensile strain experienced by the rod?

<p>0.02 (A)</p> Signup and view all the answers

Consider a scenario where a bone is subjected to a bending force. Which combination of stresses would be present within the bone?

<p>Tensile stress on one side and compressive stress on the opposite side. (C)</p> Signup and view all the answers

How does an increase in the cross-sectional area of a material influence the axial stress experienced under a constant applied force?

<p>Decreases the stress proportionally. (D)</p> Signup and view all the answers

A material with a higher Young's modulus (E) indicates what when comparing it to a material with a lower E, assuming all other factors are equal?

<p>Greater stiffness, meaning it resists deformation more effectively under stress. (B)</p> Signup and view all the answers

How does hysteresis in viscoelastic materials relate to energy during a loading cycle?

<p>Hysteresis describes delayed return of the material resulting in heat energy loss during a cycle. (B)</p> Signup and view all the answers

If a biological tissue exhibits anisotropic loading responses, this indicates:

<p>The tissue responds differently based on the direction of the applied load. (A)</p> Signup and view all the answers

In the context of viscoelastic creep response, what characterizes the second phase following initial rapid deformation under a constant load?

<p>A slow deformation rate that gradually reaches a plateau. (C)</p> Signup and view all the answers

What is the significance of the 'first-cycle effect' in the context of material fatigue?

<p>It indicates that the mechanical response during the initial load cycles differs from the response in later cycles. (A)</p> Signup and view all the answers

How can the strain, $\epsilon$, of a material sample be calculated from its original unloaded dimension and its dimension after being loaded?

<p>$\epsilon = \frac{(loaded \ dimension - unloaded \ dimension)}{(unloaded \ dimension)} \times 100 %$ (C)</p> Signup and view all the answers

In the context of a stress-strain curve, what key event is marked by the 'elastic limit'?

<p>The point at which deformation stops being reversible. (A)</p> Signup and view all the answers

During an experiment, a tissue sample is subjected to repeated loading and unloading cycles above a certain threshold. What phenomenon is most likely to occur within this tissue?

<p>Material fatigue, leading to decreased ability to withstand applied forces. (B)</p> Signup and view all the answers

Considering the properties of cortical and trabecular bone, which statement accurately describes their response to stress and strain?

<p>Cortical bone, being more dense, exhibits higher resistance to stress and lower resistance to strain compared to trabecular bone. (C)</p> Signup and view all the answers

How does the rate of loading affect the energy required to fracture bone, and what implications does this have for injury prevention?

<p>A higher loading rate increases the energy required to fracture bone, suggesting that bones can withstand rapid impacts better than slow, sustained forces. (B)</p> Signup and view all the answers

During normal activity, tendons and ligaments experience a 'toe region' characterized by the 'un-crimping' of collagen fibers. What is the significance of this region in the context of tensile load and strain?

<p>It allows the tissue to undergo slight deformation and elongation under low tensile load, preparing it for higher levels of strain without immediate damage. (A)</p> Signup and view all the answers

Following cyclic loading and unloading, the load-deformation curve of tendons and ligaments shifts to the right. What does this shift indicate about the mechanical properties of the tissue?

<p>The tissue has undergone viscoelastic adaptation, leading to increased deformation for the same load, possibly indicating fatigue or altered tissue response. (B)</p> Signup and view all the answers

How do exercise, immobilization, and rehabilitation influence the tensile strength and stiffness of ligaments, and what are the implications for injury management and recovery?

<p>Exercise leads to a 20-30% increase, immobilization causes a 50% decrease, and rehabilitation helps the ligament return to its baseline tensile strength and stiffness. (C)</p> Signup and view all the answers

A gymnast is performing a routine on the uneven bars. During a giant swing, at what point is the torque acting on the gymnast's body around the bar likely to be the greatest, assuming a constant angular acceleration?

<p>The torque remains constant throughout the entire swing, as angular acceleration is constant. (D)</p> Signup and view all the answers

A figure skater initially spinning at a constant angular velocity pulls their arms closer to their body. According to the principles of angular kinetics, which of the following statements is most accurate regarding the work and energy of the skater?

<p>The skater performs positive work, increasing their kinetic energy. (D)</p> Signup and view all the answers

During a baseball swing, the batter exerts a force on the bat over a period of time. Which of the following scenarios would result in the greatest change in the bat's momentum?

<p>Doubling both the force applied and the time of contact. (D)</p> Signup and view all the answers

Two individuals are pushing identical boxes across a floor. Individual A applies a force of 100 N over a distance of 5 meters in 10 seconds, while Individual B applies the same force over the same distance in 5 seconds. Which of the following statements accurately compares the work and power exerted by each individual?

<p>Both individuals perform the same amount of work, but Individual B generates more power. (A)</p> Signup and view all the answers

A cyclist is climbing a hill at a constant speed. Which of the following statements best describes the relationship between the force the cyclist applies to the pedals, the work done, and the power generated?

<p>The force applied is constant, the work done increases with distance traveled, and the power generated increases with time. (D)</p> Signup and view all the answers

A high jumper increases their vertical velocity from 2 m/s to 6 m/s during the jump. If the jumper's mass is 70 kg, what is the magnitude of the average net force exerted on the jumper during this phase, assuming the interaction lasts for 0.5 seconds?

<p>560 N (A)</p> Signup and view all the answers

A spinning skater changes their moment of inertia from $4 \text{ kg} \cdot \text{m}^2$ to $2 \text{ kg} \cdot \text{m}^2$ by pulling in their arms. If their initial angular velocity was $6 \text{ rad/s}$, what is their final angular velocity, assuming no external torques are acting on them?

<p>$12 \text{ rad/s}$ (C)</p> Signup and view all the answers

An athlete sprints 50 meters in 8 seconds. If their mass is 65 kg, what is the average power they developed during the sprint, assuming they accelerated constantly from rest?

<p>2031.25 W (A)</p> Signup and view all the answers

Flashcards

Muscle Force Determinants

Passive elastic structures and active contractile elements.

Length-Tension Relationship

Relates muscle tension (force) to sarcomere length.

Sarcomere Arrangement

Sarcomeres can be arranged in series (end-to-end) or in parallel (side-by-side).

Muscle Fiber Pennation Angle

Angle of muscle fibers relative to the tendon.

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Pennation Angle Implications

Connective tissue affects the risk of injury.

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Connective Tissue Elements

Cells, extracellular matrix, and tissue fluid.

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CT Extracellular Matrix (ECM)

The non-cellular component of CT, providing shape, load transmission, and physical properties.

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CT ECM (Collagen)

The most abundant protein in connective tissue, providing strength.

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Torque

A force that causes rotation.

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Inertia

An object's resistance to changes in its motion.

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Newton's 2nd Law

Force equals mass times acceleration (F=ma).

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Newton's 3rd Law

For every action, there is an equal and opposite reaction.

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Mechanical Work

The process of changing the amount of energy in a system.

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Energy

The capacity or ability to perform work.

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Work (Linear)

Force times distance (F x d).

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Power

The rate at which work is performed.

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Cartilage

Connective tissue with chondrocytes and ECM, lacking blood vessels, nerves, and lymph vessels. Relies on diffusion.

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Hyaline Cartilage

A type of cartilage providing smooth, low-friction surfaces in joints. Contains mostly Type II collagen and synovial fluid for nutrient supply.

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Tendon

Dense, regular connective tissue primarily made of Type I collagen, arranged in parallel to transmit tensile forces.

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Myotendinous Junction (MTJ)

Connection point where muscle connects to a tendon.

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Ligament

Dense, regular connective tissue with more elastic fibers than tendons; resists tensile forces to maintain joint integrity.

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Compression

Pressing or squeezing force.

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Torsion

Force causing rotation around an axis.

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Shear

Force acting parallel to a surface.

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Load-Deformation

Change in shape due to load.

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Stiffness (k)

Resistance to deformation.

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Stored Energy

Energy absorbed by a material under load.

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Stress (𝛔)

Internal force resisting an axial load, measured as Force/Area.

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Cortical Bone

More dense and stiffer, offering high resistance to stress but low resistance to strain.

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Trabecular Bone

More porous and compliant, offering low resistance to stress but high resistance to strain.

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Tendon/Ligament Toe Region

During normal activity, collagen fibers "un-crimp".

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Cyclic Loading/Unloading

Cyclic loading shifts the load-deformation curve to the right after 10 cycles.

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Ligament Adaptation

Exercise increases tensile strength & stiffness (20-30%), immobilization decreases it (50%), and rehabilitation returns it to baseline.

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Strain (ε)

The change in dimension relative to the original dimension, expressed as a percentage.

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Young's Modulus (E)

A measure of a material's stiffness, calculated as stress divided by strain in the linear region of the stress-strain curve.

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Anisotropic

Materials that exhibit different mechanical properties when loaded in different directions.

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Elastic Region

The region of a stress-strain curve where the material returns to its original shape after the stress is removed.

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Proportional Limit

The point on the stress-strain curve up to which stress is directly proportional to strain.

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Plastic Region

The region of a stress-strain curve where permanent deformation occurs.

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Viscoelastic

Materials that exhibit both solid and fluid properties, displaying time-dependent deformation.

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Hysteresis

The loss of energy during a loading and unloading cycle in viscoelastic materials, represented by the area within the hysteresis loop.

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Study Notes

Biomechanics of Sport Injury

  • Biomechanics is the study of the structure and function of biological systems using mechanics
  • It involves studying forces acting on and generated within a body
  • Biomechanics also describes the effects of forces on tissues, fluids, or materials used for diagnosis, treatment, or research

Mechanics

  • Mechanics is a branch of science studying the effects of forces and energy on bodies, materials, and structures

Injury

  • Comprehensive Definition: A bodily lesion resulting from overexposure to energy (mechanical, thermal, electrical, chemical, or radiant) interacting with the body in amounts or at rates that exceed the threshold of physiological tolerance.
  • Centers for Disease Control & Prevention (CDC)
  • Working Definition: Damage sustained by tissues of the body in response to physical trauma.
  • Zernicke, Broglio, Whiting, 2023

Mechanism

  • Mechanism is the fundamental physical process responsible for a given action, reaction, or result

Interdisciplinary Perspectives of Injury

  • Epidemiology: The study of the distribution and determinants of disease and injuries
  • Economics: Impacts costs related to injury
  • Psychology: impacts mental and emotional health
  • Sociocultural: societal norms or expectations related to injury
  • Scientific Approaches
    • Biomechanics: Studies forces
    • Physiology: Studies body
    • Medical/Clinical
    • Anatomy: Studies body structure
    • Engineering

Descriptive Epidemiology

  • It is the most common
  • Purpose: To quantify the occurrence of disease or injury according to person (who), place (where), and time (when)
  • Includes case studies, cross-sectional studies, and correlational studies

Epidemiology

  • It is the study of the distribution and determinants of disease and injury frequency within a given human population
  • Two types
    • Descriptive
    • Analytical

Descriptive Epidemiology - Specific Measures

  • Prevalence: Number of cases, new and old, existing in a population at a specific time
  • Example: 2,793 ACL reconstruction surgeries among males and females in Norway from 2005-06
  • Incidence: Number of new cases occurring in a given population during a specified time
  • Example: In Australia, 83.9 (males) and 60.1 (females) new knee injuries per 100,000 people between 2017-18
  • Sport Injury Rates: Number of new cases occurring in a population relative to athlete-exposures
  • Athlete-Exposure (A-E): Athlete participating in 1 practice, game, or hour of sport
  • Example: 0.33 ACL injuries per 1000 A-Es among NCAA female gymnasts from 1988-2004
  • Relative Risk (RR): Measure used to quantify the likelihood of injury in one group versus another
  • Formula: Ratio of injury incidence in Group A to that in Group B
  • Example: Female athletes are 4.2 times more likely to experience an ACL injury on artificial turf than males

Analytical Epidemiology

  • It uses research methods to reveal the determinants or underlying causes of injury
  • Addresses how and why injuries happen
  • Identification and analysis of injury risk according to: Intrinsic and Extrinsic Risk Factors

Factors in Analytical Epidemiology

  • Intrinsic risk factors
    • Age
    • Health
    • Injury history
    • Body composition
    • Fitness level
    • Skill level
    • Psychological factors
  • Extrinsic risk factors
    • Environment
    • Equipment
    • Opponent
    • Social Factors

Definitions

  • Catastrophic Injury
    • Fatal
    • Non-Fatal: permanent severe functional disability
    • Serious: no permanent functional disability but severe injury (e.g., fractured vertebra with no paralysis)
  • Sport Injury Type
    • Direct: injuries resulting directly from participation in sport skills
    • Indirect: events caused by systematic failure as a result of exertion in a sport or secondary complication to a non-fatal injury.

NCAA Injury Surveillance Program (ISP)

  • Timeframe: 1988/89 to 2003/04

Sport Injury Prevention and Control

  • Includes the following steps
    • Define the problem
    • Identify risk and protective factors
    • Develop and test prevention strategies
    • Assure widespread adoption

Psychological Factors

  • Factors Preceding Injury
    • Medical History
    • Psychological History
    • Somatization
    • Life Stress and Change
    • Sport Stress and Change
    • Approach of Major Competition
    • Marginal Player Status
    • Overtraining
  • Factors Associated with Injury
    • Emotional Distress
    • Injury Site
    • Pain
    • Timeliness
    • Unexpectedness
  • Factors Following Injury
    • Culpability
    • Compliance with the treatment
    • Perceived Effectiveness
    • Treatment Complications
    • Pain
    • Medication Use
    • Social Support
    • Personality Conflicts
    • Fans and the Media
    • Litigation

Tissue Types

  • Tissue
    • Epithelial
    • Simple
    • Squamous
    • Stratified
    • Cuboidal
    • Columnar
    • Nervous
    • Muscle
    • Connective tissues
      • Skeletal
      • Smooth
      • Cardiac
    • Loose
      • Irregular
      • Regular
    • Fibroelastic, Areolar, Reticular, Adipose

Types of Nerve Tissue

  • Nerve Tissue: Comprises the main parts of the nervous system, including the brain, spinal cord, peripheral nerves, and sensory organs
  • Neuron: Basic cell of nervous tissue, enables communication
    • Irritability: capacity to react to chemical/physical agents
    • Conductivity: ability to transmit impulses from one location to another

Determinants of Muscle Force Generation

  • Includes the following:
    • Structural and Functional Characteristics
    • Passive elastic structures
    • Active structures (contractile element)
    • Sarcomere arrangement
    • Pennation angle
    • Physiological cross-sectional area

Skeletal Muscle (Total Force)

  • Length-Tension Relationship

Sarcomere Arrangement

  • Includes the following:
    • Sarcomere
    • In Series
    • Combined
    • In Parallel
  • Force-Velocity Relationship

Muscle Fiber Pennation Angle

  • Angle between muscle fibers and the line of pull
  • Includes: Fascicle force, tendon/aponeurosis

Connective Tissue Elements

  • All CT Contains a Proportion of These Constituent Elements
    • Cells
    • Extracellular Matrix
    • Tissue Fluid
  • Cells
    • Resident
    • Migratory
  • Migratory Cells
    • macrophage
    • monocytes
    • basophils
    • lymphocyte
    • plasma cells
      • Collagen
    • Elastin
    • Protein Fibers - Glycoprotein -Proteoglycans - Others - fibronectin - chondronec- - tin - anchorin
  • Resident Cells
    • fibroblast -cyte
    • Chondroblast -cyte
    • osteo- blast

CT Extracellular Matrix (ECM)

  • Composition of materials outside the cell
  • Gives tissue shape, ability to transmit loads, and determines physical properties of CT (i.e., fluid [blood], soft gel-like [skin, ligament, tendon], or hard/rigid [bone, cartilage])
  • Blend of Protein fibers (collagen and elastin) and Ground substance: proteoglycans, fibronectin, chondronectin, integrins

CT ECM (Collagen)

  • Collagen fibers: most abundant protein in all CT (90% of fibers)
  • Fiber arrangement different types and properties of CT:
    • Type I (most abundant): bone, tendon, ligament
    • Type II (least abundant): cartilage
    • Type III (2nd most abundant): loose CT, skin, blood vessel walls

CT ECM (Ground Substance)

  • Composition: Proteoglycans, Fibronectin / Chondronectin
  • Integrins are important -"Mechanotransduction" = Conversion of mechanical stimuli to biological responses

CT Fluid

  • Resides in inter-cellular space (between cells)
  • Aids in the transport of materials between capillaries and cells in ECM
  • Interaction of fluid with proteoglycans gives tissue mechanical properties
  • Edema: If tissue fluid is trapped in intercellular space, can result in tissue swelling (e.g., compartment syndrome)

CT Types: Cartilage

  • Has basic elements of CT: chondrocytes (cartilage cell) and ECM
  • Free of blood vessels, nerves, and lymph vessels (relies on diffusion for nutrients and waste removal)
  • Three Types
    • Hyaline [articular]: provides a smooth surface for movement and flexibility
    • Elastic: high elasticity
    • Fibrocartilage: provides support and shock absorption

Hyaline Cartilage

  • Aka "articular" cartilage in joints
  • Characteristics of Hyaline Cartilage
    • 10% cells, 20% macromolecules (collagen), 70% fluid
    • Type II collagen (90%)
    • Smooth and glossy appearance
    • Synovial fluid provides nutrients
    • Low friction
  • Located in joint surfaces, nasal passages, and anterior ribs

Traits of Hyaline Cartilage

  • Hydrophilic proteoglycans draw water into the ECM
  • Exhibits "creep response" when compressed, fluid exudes from this cartilage

Tendon

  • Classification: dense, regular CT
  • Made primarily of type I collagen: for high tensile strength when transmitting forces
  • Fibrils arranged in parallel
  • Strain: injury to musculotendinous tissue

Ligament

  • Myotendinous junction (MTJ) connects with muscle
  • Actin filaments / Thick filaments / Z Bands / Nuclei: Sarcolemma interdigitations / Linking proteins / Subsarcolemmal densities : Collagen Type 1 / Tenocytes/Fibroblasts

Ligament

  • Classification: dense, regular CT
  • Primarily type I collagen, but more elastic fibers than tendons.
  • Fibrils arranged in different patterns
  • Resist tensile forces to maintain joint integrity and geometry
  • Weaker than tendons
  • Sprain: injury to ligament

Kinematics

  • Study of the spatial (space) and temporal (time) characteristics of motion, without regard to forces involved
  • Five Key Measures
    • Time
    • Position/Location
    • Displacement
    • Velocity
    • Acceleration

Kinematic Quantities

  • Linear Kinematics
    • Displacement (m) = d = xf - Xi
    • Velocity (m/s) = v = d/Δt
    • Acceleration (m/s²) = α = Δv/Δt
  • Angular Kinematics
  • Angular Displacement (°/rad) = Δθ = θf – θi -Angular Velocity (°/s, rad/s) = ω = Δθ/Δt -Angular Acceleration (°/s², rad/s²)= α = Δω/Δt

Kinetics

  • The study of motion with regard to the forces (or torques) involved in the production, control or modification of movement
  • Magnitude: How much force is applied?
    • Direction: Where is the force directed?
    • Location: Where is force applied?
    • Duration: What is the time over which force is applied?
    • Frequency: How often is force applied?
    • Variability: Is the force constant or variable?
    • Rate: How quickly is force applied?

Torque (Moment of Force)

  • Torque = F ×d
  • F stands for the applied force in Newtons (N)
  • d stands for the moment arm length in meters (m)
  • Units of measure: Newton-meters (Nm)

Newton's Laws of Motion

  • Law of Inertia (1st)
    • ↑ mass = ↑ inertia = ↑ resistance to linear motion or
    • ↑ distance of mass from axis of rotation = ↑ moment of inertia = ↑ resistance to angular motion
  • Law of Acceleration (2nd)
    • Acceleration is proportional to the force applied:
    • F = ma or T = Ια
  • Law of Reaction (3rd)
    • When force is applied to one body (action), the other body will return an equal and opposite force (reaction)

Relation Between Force & Motion

  • Mechanical Work: The process of changing the amount of energy in a system.
  • Energy: The capacity or ability to perform work -A change in energy is the primary source of injury

Types of Work

  • Work: Product of force (torque) applied and the displacement of a body in the direction of the force
  • Linear Work formula = Work(W) = F×d
  • Angular Work formula = Work(W) = T × Δθ Units of Work are in the same unit called joules (J)
  • Power: The rate at which Work is performed
  • Power = W/ Δt or Power = Fv; Units are J/s or watts

Impulse-Momentum Relationship

  • F x Δt (effort & time) = m x Δv (object & movement)
  • F = ma (Newton's 2nd Law); -The relationship can describe linear or angular relationships.
  • Impulse: force acting over the time for which it acts on an object.
  • Momentum: related to the object's mass and velocity

Material Mechanics

  • Includes:
    • Loading Types
    • Tissue Loading Response
    • Viscoelasticity
    • Material Fatigue and Failure

Tissue Loading Types

  • Tension
  • Shear
  • Compression
  • Bending
  • Torsion
  • Recall: Linear and Angular Work

Tissue Loading Response

  • Load Deformation (L-d) defined as the absolute change in shape or dimension of a body in response to load
  • Stiffness (k): Slope of the linear portion of an L-d curve indicating steeper slope = greater stiffness

Additional points on tissue loading response

  • Cortical bone with a large change in a load results in a small deformation.
  • Trabecular bone with a small change in a load results in large deformation

Points relating to Response

  • Stored Energy is the area under the curve as the Work = F x d
  • "The (mechanical) process of changing the amount of energy in a system"

Stress, Magnitude, & Force

  • Stress (σ [sigma]): Internal resistance to axial load. σ = F/A where
  • F = magnitude of the force applied
  • A = internal cross-sectional area where the load is distributed
  • This is where the Unit of measure: 1 Pa = 1 N/m² (Pascal)

Tissue Loading & Strain

Strain (ε): Relative change in the shape or configuration of a body:

  • ε = (dimension change)/(unloaded dimension) × 100
  • Unit of Measure is dimensionless in %

Young's Modulus of Elasticity

  • Young's Modulus of elasticity (E): Linear portion of stress-strain curve E = stress/strain = σ/ε where
  • Material A: steeper slope (higher E) and this also defines how stiff a material is.
  • Material B is a shallower slope and relates compliance

Loading Response & Tissue

  • Biological tissues have properties of both solids and fluids (viscoelastic)
    • Exhibiting anisotropic loading responses means that they respond uniquely with: "an-" (not) and "iso-" (equal) and "tropic” (direction)
    • The tissue responds differently to different loading patterns.

Graph of Biological Tissue Under Stress

  • Elastic Region is where the material is deformed but not broken
  • (A) Point up to which stress is directly proportional to strain (Young's modulus) -(B) Where deformation stops being reversible
  • Plastic Region is where material undergoes permanent Deformation -(C) The Point at which the material starts plastic deformation -(D) Max stress of material before Failure=Strength -(E) The Point of complete failure

Viscoelastic Properties

  • Have both solid and fluid properties that are tested by a biological tissue
  • (a) Perfectly elastic materials lose no energy on the return cycle.
  • (b) Hysteresis: delayed return response of viscoelastic materials resulting in heat energy loss during a cycle
    • The Shaded region in hysteresis loop represents the amount of energy loss (note: AUC) "

Creep Response in Tissue

  • "Creep Response" describes the Initial rapid deformation under constant load (first phase)
  • This is followed by slow deformation to Plateau (second phase). such as in the case of Articular cartilage

Effects on loading

  • Material Fatigue: decreased ability to withstand applied forces when repeated loads are applied above threshold
  • There is a “First-cycle effect”: mechanical response during initial load cycles differs from the response in later cycles -This creates consequence for tissue locations where materials are discontinuous (e.g., myotendinous junction)

Bone Loading & Stress

  • Cortical Bone is more dense and Stiffer high resistance to stress, low resistance to Strain
  • Trabecular Bone
    • More porous and compliant, this results in low resistance to stress but there is high resistance to strain

Impacts of Loading on Bones Under Stress

  • High loading rates have more energy to fracture a Bone compared to longitudinal loading
  • Under Load Direction of Transverse vs Longitudinal stresses
  • There will be increasing Strain rates and that cause Increased Elastic modules & overall increase of Stiffness

Relationship of Tendons & Ligaments & Loading Strains

  • Toe region has physiological range and activity with 2% strain while in the "un-crimping" of collagen fibers
  • Linear/elastic region of 2-4% strain will mean a return to original shape in tissue
  • The stage of Plastic region which describes 4-8% strain includes Microscopic tears in the tissue Finally there is the Failure point at >8-10% strain that also includes Macroscopic failures of the ligament and or tendon structure

Loadings of Tissues

  • Cyclic loading and unloading on tissue causes these loads to shift to the right after a course of ten cycles

Tissue Adaption & Synthesis

Protein synthesis & collagen degradation in humans has varying changes over the hours from 24-72hours during and post exercise

Ligament Adaption

  • Tensile Strengths and Stiffness are impacted from adaptations vs when there’s under use
  • Exercise Group: 20-30 increased adaption vs baseline
  • Immobilized - Shows a decrease off 50%
  • By Remobilization/ rehab, tissue has an easier return towards baseline

Effect of Loading on Tissues

  • Articular Cartilage has loading under certain force types versus when the load has been unlocked and the tissue recovers fluid back into the tissue "
  • Healthy tissues means that deformation return rate is higher towards the baseline

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Description

This educational content explores the functional roles and characteristics of different types of cartilage, including hyaline, elastic, and fibrocartilage. Additionally, it examines the structural significance of tendons and ligaments, highlighting the arrangement of collagen fibrils and their impact on tissue response to applied forces. It also covers the study of kinematics to enhance the understanding of human movement.

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