Functional Groups in Biological Molecules
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Functional Groups in Biological Molecules

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Questions and Answers

Which functional group is characterized as being nonpolar and often found in amino acids and proteins?

  • Amino
  • Hydroxyl
  • Methyl (correct)
  • Carboxyl
  • Which functional group behaves as an acid and is negatively charged at the pH of a cell?

  • Amino
  • Phosphate (correct)
  • Amide
  • Sulfhydryl
  • How do polar functional groups affect molecules that would otherwise be nonpolar?

  • They modify the behavior of the molecules, making them polar. (correct)
  • They increase the stability of the molecule.
  • They have no effect on the nonpolar molecules.
  • They maintain the nonpolar nature of the molecule.
  • Which functional group is essential for the formation of disulfide bonds in proteins?

    <p>Sulfhydryl</p> Signup and view all the answers

    Which functional group is primarily involved in forming ATP and phospholipids?

    <p>Phosphate</p> Signup and view all the answers

    Which functional group contributes to the hydrophilic nature of biological molecules?

    <p>Carbonyl</p> Signup and view all the answers

    Which of the following functional groups is not commonly found in proteins?

    <p>Methyl</p> Signup and view all the answers

    Which property is true for functional groups containing nitrogen, oxygen, phosphorus, and sulfur?

    <p>They are more electronegative than carbon and often polar.</p> Signup and view all the answers

    What distinguishes ribose from deoxyribose in nucleic acids?

    <p>Ribose has a hydroxyl (OH) group on the second carbon.</p> Signup and view all the answers

    Which of the following bases is found exclusively in RNA?

    <p>Uracil (U)</p> Signup and view all the answers

    What type of bond typically links amino acids together in proteins?

    <p>Peptide bonds</p> Signup and view all the answers

    What type of bond connects adjacent nucleotides in DNA and RNA?

    <p>Phosphodiester bond</p> Signup and view all the answers

    Which of the following accurately describes the structure of purine bases?

    <p>They have a double ring structure.</p> Signup and view all the answers

    Which group of amino acids can contribute to the quaternary structure of a protein?

    <p>Any amino acids that interact through their side chains</p> Signup and view all the answers

    Which nucleotide base pairs with adenine in DNA?

    <p>Thymine (T)</p> Signup and view all the answers

    Which amino acid structure is found in the smallest number of distinct forms?

    <p>Glycine</p> Signup and view all the answers

    What is the primary function of RNA in the cell?

    <p>Directing the synthesis of proteins</p> Signup and view all the answers

    What influences the interaction of amino acid side chains in a protein's quaternary structure?

    <p>The chemical properties of the side chains</p> Signup and view all the answers

    In which environment are amino and carboxyl groups of amino acids typically ionized?

    <p>At a neutral pH of 7.4</p> Signup and view all the answers

    During the formation of a phosphodiester bond, what is released?

    <p>A water molecule</p> Signup and view all the answers

    In both DNA and RNA, what determines the information carried in the molecules?

    <p>The sequence of nucleotides</p> Signup and view all the answers

    How many distinct types of proteins can potentially form due to variations in amino acids?

    <p>Thousands of distinct types</p> Signup and view all the answers

    What role do functional groups play in protein structure?

    <p>They participate in chemical reactions joining simpler molecules</p> Signup and view all the answers

    Which of the following statements about proteins is NOT correct?

    <p>Proteins consist exclusively of hydrophobic amino acids</p> Signup and view all the answers

    Study Notes

    Functional Groups In Biological Molecules

    • Functional groups are groups of one or more atoms that have specific chemical properties, regardless of what they are attached to.
    • Functional groups add chemical character to carbon chains.
    • Functional groups often contain more electronegative atoms (nitrogen, oxygen, phosphorus, sulfur) than carbon, making them polar.
    • Common functional groups in biological molecules include:
      • Amino groups - Polar, positively charged, hydrophilic, found in amino acids and proteins.
      • Amide groups - Polar, hydrophilic, found in proteins.
      • Carboxyl groups - Polar, negatively charged, hydrophilic, found in fatty acids, amino acids, and proteins.
      • Carbonyl groups - Polar, hydrophilic, found in carbohydrates and proteins.
      • Hydroxyl groups - Polar, hydrophilic, found in carbohydrates, proteins, and nucleic acids.
      • Sulfhydryl groups - Polar, form S-S disulfide bonds, found in the amino acid cysteine and proteins.
      • Methyl groups - Nonpolar, found in amino acids, proteins, and nucleic acids.
      • Phosphate groups - Polar, negatively charged, hydrophilic, found in phospholipids, nucleic acids, and ATP.

    Proteins

    • Proteins are composed of amino acids linked covalently to form chains called polypeptides.
    • Amino acids have a central carbon atom (alpha carbon) linked to:
      • An amino group (-NH2)
      • A carboxyl group (-COOH)
      • A hydrogen atom (H)
      • An R group (side chain) that varies between amino acids.
    • The R group determines the identity of each amino acid.
    • At the pH commonly found in cells (pH 7.4), the amino and carboxyl groups are ionized (charged).
    • Proteins perform a wide range of functions in the cell, including:
      • Catalyzing chemical reactions as enzymes.
      • Providing structural support.
      • Facilitating movement.

    Nucleic Acids

    • Nucleic acids, including DNA (deoxyribonucleic acid) and RNA (ribonucleic acid), are long molecules made up of nucleotides.
    • Nucleotides consist of three components:
      • A 5-carbon sugar (ribose in RNA, deoxyribose in DNA).
      • A nitrogen-containing base (purines or pyrimidines).
      • One or more phosphate groups.
    • Pyrimidine bases (cytosine (C), thymine (T), uracil (U)) have a single ring.
    • Purine bases (guanine (G), adenine (A)) have a double ring.
    • DNA contains the bases A, T, G, and C.
    • RNA contains the bases A, U, G, and C.
    • The sequence of nucleotides determines the information carried by DNA and RNA molecules.
    • Adjacent nucleotides are connected by phosphodiester bonds, formed by covalent linkage of a phosphate group in one nucleotide to the sugar unit in another nucleotide.

    Phosphodiester Bond

    • Phosphodiester bonds link successive deoxyribonucleotides, forming the backbone of the DNA strand.
    • Their formation involves the release of a water molecule.

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    Description

    Explore the essential functional groups that define biological molecules. This quiz covers their unique properties, the roles they play in amino acids, proteins, carbohydrates, and more. Test your knowledge on how these groups contribute to the chemical nature of biomolecules.

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