Podcast
Questions and Answers
How does the embryonic development of marsupials differ significantly from that of placental mammals after birth?
How does the embryonic development of marsupials differ significantly from that of placental mammals after birth?
Marsupial offspring continue a significant portion of their development in a pouch, whereas placental mammals are more developed at birth.
Describe the role of the scrotum in the male reproductive system and explain why its location is important for sperm production?
Describe the role of the scrotum in the male reproductive system and explain why its location is important for sperm production?
The scrotum houses the testicles and regulates their temperature. Its external location is crucial because sperm production requires a temperature slightly lower than the body's core temperature.
Explain why internal fertilization is essential for mammals living in terrestrial environments?
Explain why internal fertilization is essential for mammals living in terrestrial environments?
Internal fertilization protects the gametes and developing embryo from desiccation and environmental hazards, increasing the chances of successful reproduction on land.
How do monotremes differ from marsupials and placental mammals in terms of their reproductive strategy?
How do monotremes differ from marsupials and placental mammals in terms of their reproductive strategy?
In mammals, what is the primary function of the seminiferous tubules, and where are they located?
In mammals, what is the primary function of the seminiferous tubules, and where are they located?
What is the function of the Cowper's gland, prostate, and seminal vesicle in the male reproductive system?
What is the function of the Cowper's gland, prostate, and seminal vesicle in the male reproductive system?
An animal has internal fertilization and its offspring are relatively undeveloped at birth. They continue their development in a pouch. To which group does this animal MOST likely belong?
An animal has internal fertilization and its offspring are relatively undeveloped at birth. They continue their development in a pouch. To which group does this animal MOST likely belong?
How does an erection facilitate internal fertilization in mammals?
How does an erection facilitate internal fertilization in mammals?
What is the role of oestrogen in preparing the uterus for potential pregnancy, and how do its levels change throughout a full-term pregnancy?
What is the role of oestrogen in preparing the uterus for potential pregnancy, and how do its levels change throughout a full-term pregnancy?
Explain how progesterone supports pregnancy and what happens if its levels are insufficient.
Explain how progesterone supports pregnancy and what happens if its levels are insufficient.
Describe the roles of both follicle-stimulating hormone (FSH) and luteinising hormone (LH) in the ovarian cycle, but NOT during pregnancy.
Describe the roles of both follicle-stimulating hormone (FSH) and luteinising hormone (LH) in the ovarian cycle, but NOT during pregnancy.
How long is the egg viable for fertilization after ovulation, and what occurs if fertilization does not happen within this timeframe?
How long is the egg viable for fertilization after ovulation, and what occurs if fertilization does not happen within this timeframe?
What is human chorionic gonadotropin (hCG), and where is it produced? Briefly explain its significance in early pregnancy.
What is human chorionic gonadotropin (hCG), and where is it produced? Briefly explain its significance in early pregnancy.
Explain the function of gonadotropin-releasing hormone(GnRH) and its role in the menstrual cycle.
Explain the function of gonadotropin-releasing hormone(GnRH) and its role in the menstrual cycle.
Explain why oestrogen and progesterone levels dramatically drop to zero at month 9 of pregnancy.
Explain why oestrogen and progesterone levels dramatically drop to zero at month 9 of pregnancy.
If a drug was administered that blocked the effects of LH, what specific event in the ovarian cycle would be prevented?
If a drug was administered that blocked the effects of LH, what specific event in the ovarian cycle would be prevented?
During DNA replication, what specific enzyme is responsible for sealing the gaps between Okazaki fragments on the lagging strand, and why is this necessary for the integrity of the newly synthesized DNA?
During DNA replication, what specific enzyme is responsible for sealing the gaps between Okazaki fragments on the lagging strand, and why is this necessary for the integrity of the newly synthesized DNA?
Explain how DNA replication contributes to the continuity of a species, and what would happen if DNA were not accurately replicated before cell division?
Explain how DNA replication contributes to the continuity of a species, and what would happen if DNA were not accurately replicated before cell division?
Describe two key mechanisms in meiosis that generate genetic variation, and explain how this variation contributes to a species' ability to adapt and evolve over time.
Describe two key mechanisms in meiosis that generate genetic variation, and explain how this variation contributes to a species' ability to adapt and evolve over time.
Explain the role of mitosis in both the development of a multicellular organism and the maintenance of its tissues. How does mitosis contribute to the overall health and function of an organism?
Explain the role of mitosis in both the development of a multicellular organism and the maintenance of its tissues. How does mitosis contribute to the overall health and function of an organism?
Outline the central dogma of molecular biology. Briefly describe the roles of transcription and translation in polypeptide synthesis.
Outline the central dogma of molecular biology. Briefly describe the roles of transcription and translation in polypeptide synthesis.
In transcription, RNA polymerase plays a crucial role. Describe its primary function and explain what would happen if RNA polymerase was absent or non-functional.
In transcription, RNA polymerase plays a crucial role. Describe its primary function and explain what would happen if RNA polymerase was absent or non-functional.
What is the final product of polypeptide synthesis, and why are polypeptides important for cell function?
What is the final product of polypeptide synthesis, and why are polypeptides important for cell function?
Describe the significance of genetic diversity resulting from meiosis for the continuity of species, linking it to the concepts of mutation and evolution.
Describe the significance of genetic diversity resulting from meiosis for the continuity of species, linking it to the concepts of mutation and evolution.
How does internal fertilisation contribute to a higher chance of successful offspring development compared to external fertilisation?
How does internal fertilisation contribute to a higher chance of successful offspring development compared to external fertilisation?
Differentiate between the genetic outcomes of sexual and asexual reproduction, and explain how this impacts the adaptability of a population to changing environmental conditions?
Differentiate between the genetic outcomes of sexual and asexual reproduction, and explain how this impacts the adaptability of a population to changing environmental conditions?
Many aquatic animals use external fertilisation. What are the trade offs of this strategy compared to internal fertilisation?
Many aquatic animals use external fertilisation. What are the trade offs of this strategy compared to internal fertilisation?
How does the process of fertilisation ensure that the offspring receives the correct number of chromosomes, and what terms describe the number of chromosomes at each stage?
How does the process of fertilisation ensure that the offspring receives the correct number of chromosomes, and what terms describe the number of chromosomes at each stage?
During Metaphase II, where do the chromosomes align within the cell?
During Metaphase II, where do the chromosomes align within the cell?
What key event occurs during Anaphase II, and what cellular structures facilitate this process?
What key event occurs during Anaphase II, and what cellular structures facilitate this process?
In terms of energy investment by the parents, contrast the typical strategies employed in organisms that utilize external versus internal fertilisation?
In terms of energy investment by the parents, contrast the typical strategies employed in organisms that utilize external versus internal fertilisation?
Describe a scenario where asexual reproduction would be more advantageous than sexual reproduction for a plant species?
Describe a scenario where asexual reproduction would be more advantageous than sexual reproduction for a plant species?
Describe the two main events that occur during Telophase II.
Describe the two main events that occur during Telophase II.
Explain how the mobility of gametes (e.g., sperm) and the presence (or absence) of water influence the mode of fertilisation (internal vs. external) in different animal species?
Explain how the mobility of gametes (e.g., sperm) and the presence (or absence) of water influence the mode of fertilisation (internal vs. external) in different animal species?
What is the end result of meiosis? And why are these cells important?
What is the end result of meiosis? And why are these cells important?
Briefly describe the structure of DNA, mentioning its key components and how they are arranged.
Briefly describe the structure of DNA, mentioning its key components and how they are arranged.
Compare dispersal of offspring in external vs internal fertilisation.
Compare dispersal of offspring in external vs internal fertilisation.
Outline the role and mechanism of action of the enzyme helicase
during DNA replication.
Outline the role and mechanism of action of the enzyme helicase
during DNA replication.
Describe the function of DNA polymerase
during the elongation phase of DNA replication.
Describe the function of DNA polymerase
during the elongation phase of DNA replication.
Why is DNA replication essential prior to cell division?
Why is DNA replication essential prior to cell division?
During transcription, RNA polymerase moves along the DNA. Does it move along the coding stand or the template strand, and in which direction (3' to 5' or 5' to 3')?
During transcription, RNA polymerase moves along the DNA. Does it move along the coding stand or the template strand, and in which direction (3' to 5' or 5' to 3')?
Explain how the sequence of the mRNA strand produced during transcription relates to both the template strand and the coding strand of the DNA.
Explain how the sequence of the mRNA strand produced during transcription relates to both the template strand and the coding strand of the DNA.
What is the role of tRNA in the process of translation, and how does the anticodon sequence contribute to this role?
What is the role of tRNA in the process of translation, and how does the anticodon sequence contribute to this role?
Describe what happens when the ribosome encounters a stop codon on the mRNA molecule during translation.
Describe what happens when the ribosome encounters a stop codon on the mRNA molecule during translation.
If a DNA template strand has the sequence 3'-TTCAGG-5'
, what would be the corresponding mRNA sequence produced during transcription?
If a DNA template strand has the sequence 3'-TTCAGG-5'
, what would be the corresponding mRNA sequence produced during transcription?
Explain the significance of the rough endoplasmic reticulum (RER) in the context of translation and protein synthesis.
Explain the significance of the rough endoplasmic reticulum (RER) in the context of translation and protein synthesis.
During translation, what is the specific role of the small and large ribosomal subunits?
During translation, what is the specific role of the small and large ribosomal subunits?
Describe the 'transfer' process that occurs between tRNA molecules during the elongation stage of translation.
Describe the 'transfer' process that occurs between tRNA molecules during the elongation stage of translation.
Flashcards
Fertilisation
Fertilisation
Fusion of gametes (sex cells) to form a zygote.
Haploid
Haploid
Half the normal number of chromosomes in a cell.
Diploid
Diploid
The full number of chromosomes in a cell.
Sexual Reproduction
Sexual Reproduction
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Asexual Reproduction
Asexual Reproduction
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Internal Fertilisation
Internal Fertilisation
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External Fertilisation
External Fertilisation
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Gamete Fusion
Gamete Fusion
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Binary Fission
Binary Fission
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Budding
Budding
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Placental Mammals
Placental Mammals
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Marsupials
Marsupials
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Monotremes
Monotremes
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Scrotum
Scrotum
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Erection
Erection
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Egg's Viable Lifespan
Egg's Viable Lifespan
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Oestrogen's Role
Oestrogen's Role
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Progesterone's Role
Progesterone's Role
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Gonadotropin-Releasing Hormone (GnRH)
Gonadotropin-Releasing Hormone (GnRH)
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Follicle-Stimulating Hormone (FSH)
Follicle-Stimulating Hormone (FSH)
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Luteinizing Hormone (LH)
Luteinizing Hormone (LH)
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Human Chorionic Gonadotropin (hCG)
Human Chorionic Gonadotropin (hCG)
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Hormone levels at 9 months
Hormone levels at 9 months
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Meiosis II: Prophase II
Meiosis II: Prophase II
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Meiosis II: Metaphase II
Meiosis II: Metaphase II
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Meiosis II: Anaphase II
Meiosis II: Anaphase II
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Meiosis II: Telophase II
Meiosis II: Telophase II
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Products of Meiosis II
Products of Meiosis II
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DNA Replication
DNA Replication
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DNA Replication: Initiation
DNA Replication: Initiation
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DNA Replication: Elongation
DNA Replication: Elongation
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DNA Unwinding (Initiation)
DNA Unwinding (Initiation)
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Complementary Base Pairing in Transcription
Complementary Base Pairing in Transcription
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RNA Polymerase Action
RNA Polymerase Action
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Transcription Termination
Transcription Termination
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mRNA Migration
mRNA Migration
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Ribosomal Subunit Attachment
Ribosomal Subunit Attachment
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tRNA and Amino Acid Binding
tRNA and Amino Acid Binding
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Codon-Anticodon Binding
Codon-Anticodon Binding
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DNA Ligase
DNA Ligase
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Meiosis
Meiosis
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Sources of Genetic Variation in Meiosis
Sources of Genetic Variation in Meiosis
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Mitosis
Mitosis
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Polypeptide Synthesis
Polypeptide Synthesis
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Transcription
Transcription
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RNA Polymerase
RNA Polymerase
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Study Notes
- Continuity of a species relies on reproduction methods
Mechanisms of Reproduction
- Sexual and asexual reproduction are key to species' survival
Sexual Reproduction
- Requires male and female sex cells
- Fertilization results in a zygote
- Gametes fuse to create genetically unique diploid offspring, inheriting traits from both parents
Asexual Reproduction
- Offspring generated from a single parent
- Produces genetically identical offspring or clones
Fertilization
- Successful fusion of gametes (sex cells) to form a zygote
Chromosome Number
- Haploid representing half the number of chromosomes
- Diploid represents a full set of chromosomes
Animal Fertilization Types
Internal Fertilization
- Sperm and egg unite within the female body
- Zygote develops inside
- Common in terrestrial and aquatic environments
- Advantages*:
- Fewer gametes needed
- Higher fertilization chance
- Protection from disease and predators
External Fertilization
- Parents release gametes externally
- Offspring develop outside the body
- Found in terrestrial and aquatic environments
- Advantages*:
- More offspring produced
- Female can reproduce continuously
- No energy spent on gestation
- Wide offspring dispersal reduces competition
Plant Reproduction
Asexual
- Utilizes human-assisted techniques like cuttings, grafting, or biotechnology
Sexual
- Relies on flowers with male (pollen) and female (ovum) sex cells
- Pollination is necessary for reproduction
Fungi Reproduction
Asexual
- Primary mode, including budding in yeast along with spore production
Budding
- Bud forms on parent cell, nucleus divides
- After bud grows nearly as large, cytoplasm separates to create two cells Slower, more complex than binary fission
Sexual
- Two fungi temporarily fuse, create a diploid structure, produce spores through meiosis
Spores
- Released from the fruiting body (mushroom)
- Dispersed by wind, water, and animals
Hyphae
- Penetrate material, release enzymes to break down, and absorb nutrients
Bacteria Reproduction
- Binary fission is the asexual reproduction method of unicellular prokaryotic organisms
Binary Fission
- Results in two genetically identical daughter cells
- Cell elongates, building more cell wall.
- Genome replicates and attaches to membrane simultaneously
- Duplicated DNA separates towards the poles as the cell elongates
- Cleavage furrow forms, cell wall forms
- Producing two identical daughter cells
Protist Reproduction
- Reproduce asexually using binary fission and budding
Mammal Reproduction
- Sexual reproduction involves internal fertilization
Mammal Types
Placental
- Embryo grows inside the uterus
- Placenta provides nutrients, oxygen, and waste removal
- Longer pregnancy, more developed offspring
- E.g., humans, dogs, cats, giraffes, whales
Marsupials
- Viviparous births with placenta for embryonic support
- Tiny, partially developed babies continue to develop after birth in a pouch, nourished and protected there
- Joey must climb into pouch
- E.g., kangaroos, wombats, possums
Monotremes
- Lay soft-shelled eggs (oviparous)
- Underdeveloped "puggle" emerges, continues to grow and nursed by mother milk
- They have cloacas rather than vaginas
The Male Reproductive System
- Composed of paired testicles, scrotum, seminiferous tubules, epididymis, glands, vas deferens, hormones
- Erection achieved through increased blood flow, allowing internal fertilization
Male Reproductive Hormone Functions
- Testosterone enables normal male characteristics, libido, and sperm production
- LH encourages spermatogenesis and testosterone output
The Female Reproductive System
- Consists of a uterus, ovaries, fallopian tubes, cervix, follicles, and vagina
Fertilization and Implantation
- The zygote attaches and divides down the fallopian tube
- The blastocyst attaches to the uterine lining, leading to implantation
- Embryo releases hormones like hCG to sustain pregnancy
Ovarian Cycle
- Monthly egg development in the ovary, with follicular, ovulation, and luteal phases
- Follicle develops; one matures, releases estrogen, thickens endometrium; egg bursts out
Ovulation Phase Details
- Functional ovum is released from the ovary
Luteal Phase
- The ruptured follicle develops into the corpus luteum
- Secretes hormones, preparing uterus for pregnancy
- Without pregnancy, corpus luteum breaks down, initiates new cycle
Menstrual Cycle
- Endometrium cyclically prepares for pregnancy
- Shedding occurs if implantation fails
- Hypothalamus releases GnRH, stimulating FSH and LH release
- FSH and LH activate the ovary, regulate the cycle via estrogen and progesterone
- Cycle length averages 28 days
Menstruation Full Cycle
- Beginning with follicle growth that secrete estrogen.
- On day 12 follicle becomes mature, hypothalamus release mass LH
- On day 14, follicle swells and bursts which ejects egg releasing fluid into adominal cavity, fimbriae sweep egg farther into fallopian tube
- Egg must be fertilized within 12-24 hours will be dissolved away, along with the uterine lining during menstruation
Hormonal Control of Reproduction
Oestrogen Description
- Repairs, thickens uterine lining for zygote implantation
- Decrease to 0 during month 9
Progesterone Description
- Maintains endometrium lining, supports pregnancy
- Decrease to 0 during month 9
GnRH
- Triggers the pituitary gland to release important hormones
FSH Description
- Involved in follicle development to grows & mature ovum
- Ready for fertilization
LH Description
- Causes eggs to burst from the follicle and form corpus luteum, induces production of oestrogen
hCG Description
- Maintains corpus luteum, production of oestrogen and progesterone, prevention of FSH/LH
Pregnancy and Hormones
- Embryonic hCG maintains corpus luteum, progesterone production for uterine lining receptivity to embryo
- Oestrogen and progesterone interact-hypothalamus, suppresses FSH, GnRH, LH
- Physical Changes Due to Hormones*:
- Uterus enlargement, formation of a mucous plug in the cervix
- Growth and development of maternal tissue
- Breast growth
Second Trimester Change
- Oestrogen and progesterone vital, embryonic hCG declines
- Placenta produces oestrogen and progesterone
Third Trimester Change
- Increased oestrogen, receptors to bind to oxytocin
- Oxytocin triggers/maintains labor, push baby to and via cervix/vaginal opening through causing muscular contraction
Cell Replication
- Cell replication hinges on DNA replication
Mitosis
- Cell division for growth and repair, identical cells Cell division enables growth, repair, maintenance, and reproduction.
Mitosis Stages
- Interphase, Prophase, Metaphase, Anaphase, Telophase, Cytokinesis
- DNA replication occurs where? Interphase.
- Chromosomes coil, align when in what phase? Prophase in equator of the cell.
- Chromosomes line up during metaphase.
- Chromatids pulled apart during anaphase.
- New membranes form when? Telophase.
- Cell divides in cytokinesis.
Meiosis
- Creates genetically unique gametes for sexual reproduction
Meiosis I
- Number of chromosomes don't change despite is what? sister chromatid replication occurs during interphase.
- Chromosomes coil, nuclear membrane dissolves in what phase? prophase
- Double stranded chromosomes pair, create new genetic variations when? prophase Spindle binds dissolves fibres during what phase?
Meiosis II
- The two sister of each sister separated what phase? prophase II
- Line up during? metaphase II
- Towards the opposite what happens? separated during anaphase II
- Membranes forms, chromosome sets split in new cells what occurs? telophase II
DNA Replication
Nitrogenous
- Pairs A-T and G-C.
- Double stranded.
- Bases bind, backbone unzips, creates two DNA molecules.
Initiation Phase
- Helicase progressive unwinds, destroys hydrogen bonds
Elongation Phase
- A RNA is started with Primase added
- Complementatry free nucleotides added w/ DNA polymerase
- Errors are fixed by splicing and replacing w/ DNA polymerase
Termination Phase
- Two strands are sealed w/ ligase seals which then recoils into 2 double helixes
DNA Replication Impact on Species
- Needed, copies information important to life
- Without before mitosis and meiosis, cells die without.
Meiosis variation
Mitosis Growth
- Development, tissue is replaced, mature.
Polypeptide Synthesis
- Creates organic compounds that create the essential function and are building blocks of proteins
Transcription
- Template is is the gene that the complementary copy uses to get copy
- Begins RNA polymerase and is broken w/ template strand
Translation
- Process uses RNA to specify amino acids
Translation-Step Two
- Subunit attaches
Translation-Step Three
- translation in ribosomes
- rough endoplasmic reluculum surface
Translation-Four/Five
- Found in cytoplasm called anticodon
Translation- Five
Translation
- Code speficifie
-Translation - step by 6-9
- Repeat w/tRNA binds
- process builds w/stop codon
- unit separates
- bond is folded
MRna function
- Bases for gene match to RNA TRNA function - binds amino acid
Gene Expression
- Dna convert protein Transcription- rna carry genes. Translation - amino bases bonded
Structure and Function of Proteins
Structure primary
- sequence aminos
Sequence secondary
Quaterinary
- two proteins are combined
Function
- Support bones
- speed reactions
- Move proteins Defence Signalling:
- Movement
Amino Acid
- rna adds and transfers
Dna -
phenotype
- Expression of enviromental
- soil:
- water
- Genotype + Enfactors =
Alleles
- Form is each allele
Genetics
- Uppercase
Homo
- For both trats
Hetero
- Said to be trait or recessive
Autosomal
- Non sex.
Sex linked
Conditions
- red green colorblindness
- muscular dystrophy
Co domination
- express of the domincae
- the sharing .
SNP
- polymorphic genetic SNP - differences a Add
mutation
- Dna
Deletion
- Loss
Substitution.
- Replace
Technologies inheritance.
Polymerase chain reaction
- Dna happens 2
Population.
Preservation/
Evolution
- Diseseae disrder.
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