Four Criteria of a Neurotransmitter

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Questions and Answers

What would be the effect on serotonin levels if you inhibit SERT?

  • Serotonin would not be produced by the neuron
  • Serotonin levels would remain the same in the extracellular state
  • Serotonin levels would decrease in the extracellular state
  • Serotonin levels would increase in the extracellular state (correct)

What is the role of acetylcholinesterase (AChE) in neuronal signaling?

  • AChE breaks down acetylcholine after release from synaptic vesicles (correct)
  • AChE converts glutamate into GABA for synaptic transmission
  • AChE transports acetylcholine back into the neuron for recycling
  • AChE inhibits the release of acetylcholine from neurons

What is the fate of choline after it is transported back into the neuron by choline transporter (CHT)?

  • It reacts with Acetyl CoA to form GABA
  • It is converted back to acetylcholine (correct)
  • It is excreted as waste from the neuron
  • It triggers the release of serotonin from the neuron

How does Aricept (an acetylcholinesterase inhibitor) impact neuronal signaling?

<p>It inhibits the breakdown of acetylcholine, leading to increased levels (B)</p> Signup and view all the answers

What role do glial cells (astrocytes) play in neurotransmitter recycling?

<p>Astrocytes take up neurotransmitters like GABA, recycle them, and provide precursors for neurotransmitter synthesis (C)</p> Signup and view all the answers

What is a requirement for a substance to be classified as a neurotransmitter?

<p>It must be released via exocytosis from vesicles (A)</p> Signup and view all the answers

Which neurotransmitter is reduced in Alzheimer's disease?

<p>Acetylcholine (B)</p> Signup and view all the answers

What differentiates classic small molecule neurotransmitters from neuropeptides?

<p>Duration of action (C)</p> Signup and view all the answers

Which neurotransmitter is also known as noradrenaline?

<p>Norepinephrine (D)</p> Signup and view all the answers

What is the role of monoamine oxidase (MAO) in neurotransmission?

<p>Breakdown of monoamine neurotransmitters intracellularly (A)</p> Signup and view all the answers

Which neurotransmitter is most common as an inhibitory transmitter throughout the central nervous system (CNS) and body?

<p>GABA (C)</p> Signup and view all the answers

What do dopamine neurons not express in the biosynthetic pathway of catecholamines?

<p>Final 2 enzymes in the pathway (B)</p> Signup and view all the answers

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