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12 Questions

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Four Criteria of a Neurotransmitter

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Questions and Answers

What would be the effect on serotonin levels if you inhibit SERT?

Serotonin would not be produced by the neuron

Serotonin levels would remain the same in the extracellular state

Serotonin levels would decrease in the extracellular state

Serotonin levels would increase in the extracellular state (correct)

What is the role of acetylcholinesterase (AChE) in neuronal signaling?

AChE breaks down acetylcholine after release from synaptic vesicles (correct)

AChE converts glutamate into GABA for synaptic transmission

AChE transports acetylcholine back into the neuron for recycling

AChE inhibits the release of acetylcholine from neurons

What is the fate of choline after it is transported back into the neuron by choline transporter (CHT)?

It reacts with Acetyl CoA to form GABA

It is converted back to acetylcholine (correct)

It is excreted as waste from the neuron

It triggers the release of serotonin from the neuron

How does Aricept (an acetylcholinesterase inhibitor) impact neuronal signaling?

It inhibits the breakdown of acetylcholine, leading to increased levels Signup and view all the answers

What role do glial cells (astrocytes) play in neurotransmitter recycling?

Astrocytes take up neurotransmitters like GABA, recycle them, and provide precursors for neurotransmitter synthesis Signup and view all the answers

What is a requirement for a substance to be classified as a neurotransmitter?

It must be released via exocytosis from vesicles Signup and view all the answers

Which neurotransmitter is reduced in Alzheimer's disease?

Acetylcholine Signup and view all the answers

What differentiates classic small molecule neurotransmitters from neuropeptides?

Duration of action Signup and view all the answers

Which neurotransmitter is also known as noradrenaline?

Norepinephrine Signup and view all the answers

What is the role of monoamine oxidase (MAO) in neurotransmission?

Breakdown of monoamine neurotransmitters intracellularly Signup and view all the answers

Which neurotransmitter is most common as an inhibitory transmitter throughout the central nervous system (CNS) and body?

GABA Signup and view all the answers

What do dopamine neurons not express in the biosynthetic pathway of catecholamines?

Final 2 enzymes in the pathway Signup and view all the answers