Podcast
Questions and Answers
Where is dopamine mainly synthesized?
Where is dopamine mainly synthesized?
- In the synaptic cleft
- Inside dopaminergic neurons (correct)
- In the presynaptic neuron's terminal
- Within the postsynaptic neuron
What triggers the release of dopamine from vesicles?
What triggers the release of dopamine from vesicles?
- Enzymatic degradation
- Re-uptake into the presynaptic neuron
- Signal reaching the postsynaptic neuron
- Signal reaching the presynaptic neuron's terminal (correct)
How is the action of dopamine terminated?
How is the action of dopamine terminated?
- Synthesis from L-dopa
- Storage in vesicles
- Binding to postsynaptic receptors
- Re-uptake, enzymatic degradation, and diffusion (correct)
Where does released dopamine bind after being released from vesicles?
Where does released dopamine bind after being released from vesicles?
What are the enzymes involved in dopamine breakdown?
What are the enzymes involved in dopamine breakdown?
What is responsible for the reabsorption of dopamine back into the presynaptic neuron?
What is responsible for the reabsorption of dopamine back into the presynaptic neuron?
What is the main function of the vesicular monoamine transporter (VMAT-2)?
What is the main function of the vesicular monoamine transporter (VMAT-2)?
What is the process by which dopamine is released into the synaptic cleft?
What is the process by which dopamine is released into the synaptic cleft?
Which type of receptor is located on the presynaptic neuron and plays a role in regulating the amount of dopamine released?
Which type of receptor is located on the presynaptic neuron and plays a role in regulating the amount of dopamine released?
What is the main effect of activating D1 family receptors?
What is the main effect of activating D1 family receptors?
Which enzyme is associated with mitochondrial membranes and responsible for breaking down neurotransmitters, including dopamine, into inactive metabolites?
Which enzyme is associated with mitochondrial membranes and responsible for breaking down neurotransmitters, including dopamine, into inactive metabolites?
Where is Catechol-O-methyltransferase (COMT) localized within the cell?
Where is Catechol-O-methyltransferase (COMT) localized within the cell?
What is the primary role of Catechol-O-methyltransferase (COMT) in dopamine metabolism?
What is the primary role of Catechol-O-methyltransferase (COMT) in dopamine metabolism?
