Folic Acid Synthesis Quiz
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Questions and Answers

What is the role of folic acid in DNA and RNA synthesis?

  • Enhancing protein synthesis
  • Competing with PABA
  • Required for the synthesis of DNA and RNA (correct)
  • Inhibiting bacterial growth
  • Why do sulfonamides inhibit folic acid synthesis in bacteria?

  • They act bactericidal
  • They have a synergistic effect with trimethoprim
  • They compete with PABA (correct)
  • They enhance bacterial growth
  • What is the antibacterial spectrum of sulfonamides?

  • Gram-positive specific
  • Narrow-spectrum bactericidal
  • Broad-spectrum bacteriostatic (correct)
  • Fungicidal
  • How does trimethoprim interact with sulphamethoxazole?

    <p>They act synergistically</p> Signup and view all the answers

    Which antibiotic combination is bactericidal?

    <p>Co-trimoxazole</p> Signup and view all the answers

    What is the therapeutic use of Co-trimoxazole?

    <p>Prophylaxis of urinary tract infections</p> Signup and view all the answers

    How do trimethoprim and sulfamethoxazole act when combined in Co-trimoxazole?

    <p>They block folic acid synthesis sequentially</p> Signup and view all the answers

    What is a common adverse effect of sulfonamides?

    <p>Hypersensitivity reactions</p> Signup and view all the answers

    What is the role of beta-lactamase inhibitors like clavulanic acid?

    <p>Extend the spectrum of penicillins by preventing their breakdown</p> Signup and view all the answers

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