Folic Acid Synthesis Quiz

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Questions and Answers

What is the role of folic acid in DNA and RNA synthesis?

  • Enhancing protein synthesis
  • Competing with PABA
  • Required for the synthesis of DNA and RNA (correct)
  • Inhibiting bacterial growth

Why do sulfonamides inhibit folic acid synthesis in bacteria?

  • They act bactericidal
  • They have a synergistic effect with trimethoprim
  • They compete with PABA (correct)
  • They enhance bacterial growth

What is the antibacterial spectrum of sulfonamides?

  • Gram-positive specific
  • Narrow-spectrum bactericidal
  • Broad-spectrum bacteriostatic (correct)
  • Fungicidal

How does trimethoprim interact with sulphamethoxazole?

<p>They act synergistically (A)</p> Signup and view all the answers

Which antibiotic combination is bactericidal?

<p>Co-trimoxazole (C)</p> Signup and view all the answers

What is the therapeutic use of Co-trimoxazole?

<p>Prophylaxis of urinary tract infections (B)</p> Signup and view all the answers

How do trimethoprim and sulfamethoxazole act when combined in Co-trimoxazole?

<p>They block folic acid synthesis sequentially (B)</p> Signup and view all the answers

What is a common adverse effect of sulfonamides?

<p>Hypersensitivity reactions (D)</p> Signup and view all the answers

What is the role of beta-lactamase inhibitors like clavulanic acid?

<p>Extend the spectrum of penicillins by preventing their breakdown (D)</p> Signup and view all the answers

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