9 Questions
What is the role of folic acid in DNA and RNA synthesis?
Required for the synthesis of DNA and RNA
Why do sulfonamides inhibit folic acid synthesis in bacteria?
They compete with PABA
What is the antibacterial spectrum of sulfonamides?
Broad-spectrum bacteriostatic
How does trimethoprim interact with sulphamethoxazole?
They act synergistically
Which antibiotic combination is bactericidal?
Co-trimoxazole
What is the therapeutic use of Co-trimoxazole?
Prophylaxis of urinary tract infections
How do trimethoprim and sulfamethoxazole act when combined in Co-trimoxazole?
They block folic acid synthesis sequentially
What is a common adverse effect of sulfonamides?
Hypersensitivity reactions
What is the role of beta-lactamase inhibitors like clavulanic acid?
Extend the spectrum of penicillins by preventing their breakdown
Test your knowledge on the synthesis of folic acid, its importance for DNA and RNA production, and how bacteria and sulfonamides interact with this process.
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