Folic Acid Synthesis and Inhibition Quiz
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Questions and Answers

What is the therapeutic use of co-trimoxazole?

  • Bacterial endocarditis
  • Typhoid
  • Urinary tract infections (correct)
  • Bacterial prostatitis
  • Which adverse effect is associated with sulfonamides?

  • Kidney stones (correct)
  • Hypertension
  • Hyperglycemia
  • Hypothyroidism
  • What is the role of folic acid in bacteria?

  • Is required for DNA synthesis
  • Serves as a building block for RNA synthesis
  • Competes with PABA for bacterial folic acid synthesis (correct)
  • Acts synergistically with sulfamethoxazole
  • Which component competes with PABA for bacterial folic acid synthesis?

    <p>Sulfonamides</p> Signup and view all the answers

    What is the antibacterial spectrum of sulfonamides?

    <p>Broad-spectrum bacteriostatic</p> Signup and view all the answers

    How do beta lactamase inhibitors extend the spectrum of penicillins?

    <p>By preventing penicillin breakdown by beta lactamases</p> Signup and view all the answers

    What is the mechanism of action of trimethoprim?

    <p>Works synergistically with sulfamethoxazole</p> Signup and view all the answers

    How is the combination of trimethoprim and sulphamethoxazole (co-trimoxazole) different from their individual actions?

    <p>The combination is bactericidal while individually they are bacteriostatic</p> Signup and view all the answers

    What is the major therapeutic use of Penicillin G?

    <p>Pneumonia</p> Signup and view all the answers

    Which combination is considered bactericidal?

    <p>Co-trimoxazole (sulfamethoxazole-trimethoprin)</p> Signup and view all the answers

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