10 Questions
What is the therapeutic use of co-trimoxazole?
Urinary tract infections
Which adverse effect is associated with sulfonamides?
Kidney stones
What is the role of folic acid in bacteria?
Competes with PABA for bacterial folic acid synthesis
Which component competes with PABA for bacterial folic acid synthesis?
Sulfonamides
What is the antibacterial spectrum of sulfonamides?
Broad-spectrum bacteriostatic
How do beta lactamase inhibitors extend the spectrum of penicillins?
By preventing penicillin breakdown by beta lactamases
What is the mechanism of action of trimethoprim?
Works synergistically with sulfamethoxazole
How is the combination of trimethoprim and sulphamethoxazole (co-trimoxazole) different from their individual actions?
The combination is bactericidal while individually they are bacteriostatic
What is the major therapeutic use of Penicillin G?
Pneumonia
Which combination is considered bactericidal?
Co-trimoxazole (sulfamethoxazole-trimethoprin)
Test your knowledge of the synthesis of folic acid, the role of folic acid in DNA and RNA synthesis, and the mechanism of inhibition by sulfonamides. Learn about how bacteria produce their own folic acid and the competition with PABA in the process.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
