Folic Acid Synthesis and Inhibition Quiz

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Questions and Answers

What is the therapeutic use of co-trimoxazole?

  • Bacterial endocarditis
  • Typhoid
  • Urinary tract infections (correct)
  • Bacterial prostatitis

Which adverse effect is associated with sulfonamides?

  • Kidney stones (correct)
  • Hypertension
  • Hyperglycemia
  • Hypothyroidism

What is the role of folic acid in bacteria?

  • Is required for DNA synthesis
  • Serves as a building block for RNA synthesis
  • Competes with PABA for bacterial folic acid synthesis (correct)
  • Acts synergistically with sulfamethoxazole

Which component competes with PABA for bacterial folic acid synthesis?

<p>Sulfonamides (B)</p> Signup and view all the answers

What is the antibacterial spectrum of sulfonamides?

<p>Broad-spectrum bacteriostatic (B)</p> Signup and view all the answers

How do beta lactamase inhibitors extend the spectrum of penicillins?

<p>By preventing penicillin breakdown by beta lactamases (B)</p> Signup and view all the answers

What is the mechanism of action of trimethoprim?

<p>Works synergistically with sulfamethoxazole (D)</p> Signup and view all the answers

How is the combination of trimethoprim and sulphamethoxazole (co-trimoxazole) different from their individual actions?

<p>The combination is bactericidal while individually they are bacteriostatic (C)</p> Signup and view all the answers

What is the major therapeutic use of Penicillin G?

<p>Pneumonia (D)</p> Signup and view all the answers

Which combination is considered bactericidal?

<p>Co-trimoxazole (sulfamethoxazole-trimethoprin) (A)</p> Signup and view all the answers

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