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Antimicrobial Drugs Quiz
10 Questions
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Antimicrobial Drugs Quiz

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Questions and Answers

What is the mechanism of action of sulfonamides?

  • They inhibit bacterial cell wall synthesis
  • They directly kill bacteria
  • They interfere with bacterial folic acid synthesis (correct)
  • They disrupt bacterial DNA replication

    • When were sulfonamides first used as antimicrobials?

  • 1960’s
  • 1940’s
  • 1930’s (correct)
  • 1950’s

    • What is the role of paraaminobenzoic acid (PABA) in bacteria?

  • A building block for bacterial cell wall
  • Required for folic acid synthesis (correct)
  • Involved in bacterial protein synthesis
  • Essential for bacterial DNA replication

    • Why are only a few sulfonamides used in clinical medicine?

    <p>Due to poor penetration, coverage, and resistance</p> Signup and view all the answers

    What was introduced in the 1960’s as a complement to sulfonamides?

    <p>Trimethoprim</p> Signup and view all the answers

    What is the role of sulfonamides in inhibiting bacterial folic acid synthesis?

    <p>Competitively inhibiting PABA utilization in folic acid synthesis</p> Signup and view all the answers

    Why are only a few sulfonamides used in clinical medicine?

    <p>Poor penetration, coverage, and resistance</p> Signup and view all the answers

    What is the main reason for combining sulfonamides and trimethoprim?

    <p>To provide synergism and broader spectrum of action</p> Signup and view all the answers

    What is the mechanism of action of sulfonamides?

    <p>Competitively inhibiting bacterial folic acid synthesis</p> Signup and view all the answers

    Why are sulfonamides considered bacteriostatic?

    <p>They inhibit bacterial folic acid synthesis</p> Signup and view all the answers

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