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Antimicrobial Drugs Quiz

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Questions and Answers

What is the mechanism of action of sulfonamides?

They inhibit bacterial cell wall synthesis

They directly kill bacteria

They interfere with bacterial folic acid synthesis (correct)

They disrupt bacterial DNA replication

When were sulfonamides first used as antimicrobials?

1960’s

1940’s

1930’s (correct)

1950’s

What is the role of paraaminobenzoic acid (PABA) in bacteria?

A building block for bacterial cell wall

Required for folic acid synthesis (correct)

Involved in bacterial protein synthesis

Essential for bacterial DNA replication

Why are only a few sulfonamides used in clinical medicine?

Due to poor penetration, coverage, and resistance Signup and view all the answers

What was introduced in the 1960’s as a complement to sulfonamides?

Trimethoprim Signup and view all the answers

What is the role of sulfonamides in inhibiting bacterial folic acid synthesis?

Competitively inhibiting PABA utilization in folic acid synthesis Signup and view all the answers

Why are only a few sulfonamides used in clinical medicine?

Poor penetration, coverage, and resistance Signup and view all the answers

What is the main reason for combining sulfonamides and trimethoprim?

To provide synergism and broader spectrum of action Signup and view all the answers

What is the mechanism of action of sulfonamides?

Competitively inhibiting bacterial folic acid synthesis Signup and view all the answers

Why are sulfonamides considered bacteriostatic?

They inhibit bacterial folic acid synthesis Signup and view all the answers

Antimicrobial Drugs Quiz

Choose a study mode

Podcast

Questions and Answers

What is the mechanism of action of sulfonamides?

When were sulfonamides first used as antimicrobials?

What is the role of paraaminobenzoic acid (PABA) in bacteria?

Why are only a few sulfonamides used in clinical medicine?

What was introduced in the 1960’s as a complement to sulfonamides?

What is the role of sulfonamides in inhibiting bacterial folic acid synthesis?

Why are only a few sulfonamides used in clinical medicine?

What is the main reason for combining sulfonamides and trimethoprim?

What is the mechanism of action of sulfonamides?

Why are sulfonamides considered bacteriostatic?

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