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Questions and Answers
What is the mechanism of action of sulfonamides?
What is the mechanism of action of sulfonamides?
- They inhibit bacterial cell wall synthesis
- They directly kill bacteria
- They interfere with bacterial folic acid synthesis (correct)
- They disrupt bacterial DNA replication
When were sulfonamides first used as antimicrobials?
When were sulfonamides first used as antimicrobials?
- 1960’s
- 1940’s
- 1930’s (correct)
- 1950’s
What is the role of paraaminobenzoic acid (PABA) in bacteria?
What is the role of paraaminobenzoic acid (PABA) in bacteria?
- A building block for bacterial cell wall
- Required for folic acid synthesis (correct)
- Involved in bacterial protein synthesis
- Essential for bacterial DNA replication
Why are only a few sulfonamides used in clinical medicine?
Why are only a few sulfonamides used in clinical medicine?
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What was introduced in the 1960’s as a complement to sulfonamides?
What was introduced in the 1960’s as a complement to sulfonamides?
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What is the role of sulfonamides in inhibiting bacterial folic acid synthesis?
What is the role of sulfonamides in inhibiting bacterial folic acid synthesis?
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Why are only a few sulfonamides used in clinical medicine?
Why are only a few sulfonamides used in clinical medicine?
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What is the main reason for combining sulfonamides and trimethoprim?
What is the main reason for combining sulfonamides and trimethoprim?
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What is the mechanism of action of sulfonamides?
What is the mechanism of action of sulfonamides?
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Why are sulfonamides considered bacteriostatic?
Why are sulfonamides considered bacteriostatic?
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