Fluticasone and Salmeterol Overview

What are some brand names for Fluticasone/Salmeterol?

What is the drug class for Fluticasone/Salmeterol?

What are the indications for Fluticasone/Salmeterol?

What is the mechanism of action of Fluticasone?

How does Salmeterol work?

What are the contraindications for Fluticasone/Salmeterol?

What is the Black Box warning for Fluticasone/Salmeterol?

What are common adverse reactions to Fluticasone/Salmeterol?

What formulations are available for Fluticasone/Salmeterol?

Fluticasone/Salmeterol Overview

Commonly marketed as Advair Diskus, Advair HFA, and AirDuo RespiClick.
Combines an inhaled corticosteroid with a long-acting beta2 agonist.

Drug Classification

Categorized as an inhaled corticosteroid and long-acting beta2 agonist.

Indications for Use

Approved for the management of asthma and Chronic Obstructive Pulmonary Disease (COPD).

Mechanism of Action (Fluticasone)

Exhibits anti-inflammatory activity.
Possesses immunosuppressive properties and inhibits cellular proliferation.

Mechanism of Action (Salmeterol)

Relaxes bronchial smooth muscle through selective action on beta2 receptors, minimally affecting the heart rate.

Contraindications

Not recommended for the treatment of status asthmaticus or acute exacerbations of asthma or COPD.
Contraindicated in patients with a hypersensitivity to milk proteins.

Black Box Warning

Contains a safety alert regarding the use of long-acting beta agonists in combination with inhaled corticosteroids, indicating potential risks.

Adverse Reactions

Possible side effects include upper respiratory tract infections, pneumonia, and pharyngitis.

Formulations Available

Available in aerosol and powder forms for inhalation.

This quiz covers the pharmacology of Fluticasone and Salmeterol, including their classifications and mechanisms of action. Learn about their approved uses for asthma and COPD management and essential safety information such as contraindications and black box warnings.