Questions and Answers
What are some brand names for Fluticasone/Salmeterol?
What is the drug class for Fluticasone/Salmeterol?
Inhaled corticosteroid, long-acting beta2 agonist
What are the indications for Fluticasone/Salmeterol?
Asthma, COPD
What is the mechanism of action of Fluticasone?
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How does Salmeterol work?
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What are the contraindications for Fluticasone/Salmeterol?
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What is the Black Box warning for Fluticasone/Salmeterol?
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What are common adverse reactions to Fluticasone/Salmeterol?
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What formulations are available for Fluticasone/Salmeterol?
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Study Notes
Fluticasone/Salmeterol Overview
- Commonly marketed as Advair Diskus, Advair HFA, and AirDuo RespiClick.
- Combines an inhaled corticosteroid with a long-acting beta2 agonist.
Drug Classification
- Categorized as an inhaled corticosteroid and long-acting beta2 agonist.
Indications for Use
- Approved for the management of asthma and Chronic Obstructive Pulmonary Disease (COPD).
Mechanism of Action (Fluticasone)
- Exhibits anti-inflammatory activity.
- Possesses immunosuppressive properties and inhibits cellular proliferation.
Mechanism of Action (Salmeterol)
- Relaxes bronchial smooth muscle through selective action on beta2 receptors, minimally affecting the heart rate.
Contraindications
- Not recommended for the treatment of status asthmaticus or acute exacerbations of asthma or COPD.
- Contraindicated in patients with a hypersensitivity to milk proteins.
Black Box Warning
- Contains a safety alert regarding the use of long-acting beta agonists in combination with inhaled corticosteroids, indicating potential risks.
Adverse Reactions
- Possible side effects include upper respiratory tract infections, pneumonia, and pharyngitis.
Formulations Available
- Available in aerosol and powder forms for inhalation.
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Description
This quiz covers the pharmacology of Fluticasone and Salmeterol, including their classifications and mechanisms of action. Learn about their approved uses for asthma and COPD management and essential safety information such as contraindications and black box warnings.